Results 21 to 30 of about 4,033 (193)

Proteogenomic characterization of cholangiocarcinoma

Hepatology, EarlyView., 2022
Proteogenomic characterization of cholangiocarcinoma with therapeutic strategies Abstract Background and Aims Cholangiocarcinoma (CCA) is a highly heterogeneous cancer with limited understanding and few effective therapeutic approaches. We aimed at providing a proteogenomic CCA characterization to inform biological processes and treatment ...
Mengjie Deng, Peng Ran, Lingli Chen, Yunzhi Wang, Zixiang Yu, Ke Cai, Jinwen Feng, Zhaoyu Qin, Yanan Yin, Subei Tan, Yang Liu, Chen Xu, Guoming Shi, Yuan Ji, Jian‐Yuan Zhao, Jian Zhou, Jia Fan, Yingyong Hou, Chen Ding   +18 more
wiley   +1 more source

Study of the Contents of Analogues of Aristolochic Acid in Houttuynia cordata by Ultra-High Performance Liquid Chromatography Tandem Mass Spectrometry

Foods, 2022
In this study, a new and simple method was established for the simultaneous determination of analogues of aristolochic acids (aristolochic acid I, aristolochic acid II, aristolactam I and aristolactam AII) in Houttuynia cordata by ultra-high performance ...
Xuan Yu, Yuan Gao, Ying Xu, Xian Guo, Lan Guo, Ting Tan, Fan Liu, Yiqun Wan   +7 more
doaj   +1 more source

Preventing Aristolochic Acid Nephropathy [PDF]

Clinical Journal of the American Society of Nephrology, 2015
Reports of an epidemic of rapidly progressive fibrosing interstitial nephritis first surfaced in the early 1990s in a cohort of Belgium women ([1][1]). The causative agent was found to be aristolochic acid ([2][2]), a family of compounds found in the plant genus Aristolochiacaea , including ...
Anandagoda, Nelomi, Lord, Graham M.
openaire   +3 more sources

Molecular Characterization of Microrna Interference and Aristolochic Acid Intoxication Found in Upper Tract Urothelial Carcinoma in Patients with Balkan Endemic Nephropathy: A Systematic Review of the Current Literature

Balkan Journal of Medical Genetics, 2022
The term “aristolochic acid nephropathy” (AAN) is used to include any form of toxic interstitial nephropathy that is caused either by ingestion of plants containing aristolochic acids (AA) or by the environmental contaminants in food such as in Balkan ...
Bašić D, Ignjatović I, Janković Veličković Lj, Veljković A   +3 more
doaj   +1 more source

Detection and Removal of Aristolochic Acid in Natural Plants, Pharmaceuticals, and Environmental and Biological Samples: A Review

Molecules, 2023
Aristolochic acids (AAs) are a toxic substance present in certain natural plants. Direct human exposure to these plants containing AAs leads to a severe and irreversible condition known as aristolochic acid nephropathy (AAN).
Changhong Wang, Yunchao Liu, Jintai Han, Wenying Li, Jing Sun, Yinan Wang   +5 more
doaj   +1 more source

Rapid Analysis of Aristolochic Acid Analogues in Traditional Chinese Patent Medicine by LC-MS/MS

Journal of Analytical Methods in Chemistry, 2020
Aristolochic acids have been demonstrated to have renal toxicity, cause carcinogenesis, and may cause gene mutations. A series of risk control measurements have been adopted worldwide since 1990s.
Jing Liu, Yang Liu, Yingxue Wu, Zhong Dai, Shuangcheng Ma   +4 more
doaj   +1 more source

Enterohepatic Recirculation-Mediated Reabsorption of Aristolochic Acid I: Revealed by Toxicokinetics and Metabolite Identification in Rats. [PDF]

Toxics
Huang L, Nie L, Ye X, Lin Z, Liu Y, Wei F.   +5 more
europepmc   +3 more sources

Aristolochic acids affect the feeding behaviour and development of Battus polydamas archidamas larvae (Lepidoptera: Papilionidae: Troidini)

European Journal of Entomology, 2009
The feeding behaviour of specialist butterflies may be affected by the mechanical and chemical characteristics of the tissues of their host-plants. Larvae of the butterfly, Battus polydamas archidamas feed only on Aristolochia chilensis, which contains ...
Carlos F. PINTO, Alejandra J. TRONCOSO, Alejandro URZÚA, Hermann M. NIEMEYER   +3 more
doaj   +1 more source

Climate change-related warming-induced shifts in leaf chemical traits favor nutrition of the specialist herbivore Battus polydamas archidamas

Frontiers in Ecology and Evolution, 2023
One of the major impacts of climate change is increasing global temperatures. Because warming is expected to affect plant morphological and chemical traits, it may therefore also influence plant interactions with other trophic levels, including ...
Marcia González-Teuber, Marcia González-Teuber, Valeria Palma-Onetto, Carolina Aguirre, Carolina Aguirre, Alfredo J. Ibáñez, Alfredo J. Ibáñez, Axel Mithöfer   +7 more
doaj   +1 more source

Lycopene attenuates the inflammation and apoptosis in aristolochic acid nephropathy by targeting the Nrf2 antioxidant system

Redox Biology, 2022
Lycopene (LYC) is a carotenoid, has antioxidant properties. This study investigated whether lycopene attenuates aristolochic acids (AAs) -induced chronic kidney disease.
Yu Wang, Zhihui Liu, Jun Ma, Qingyang Xv, Hongxin Gao, Hang Yin, Ge Yan, Xiaowen Jiang, Wenhui Yu   +8 more
doaj   +1 more source