Results 41 to 50 of about 105,306 (266)

Engineering Pendant Group Chemistry to Control Hydrophilicity and Oxidative Degradation of Thioketal‐Based Biomaterials

open access: yesAdvanced Functional Materials, EarlyView.
Thioketal (TK) polymers are promising biomaterials due to their selective biodegradation by reactive oxygen species (ROS), but they respond slowly to physiologic doses of ROS. Here, the TK bond's pendant groups are modified to enhance the degradation of TK‐based implants both in vitro and in vivo.
Karina A. Bruce   +6 more
wiley   +1 more source

Design and testing of ultrasound probe adapters for a robotic imaging platform

open access: yesScientific Reports
Medical imaging-based triage is a critical tool for emergency medicine in both civilian and military settings. Ultrasound imaging can be used to rapidly identify free fluid in abdominal and thoracic cavities which could necessitate immediate surgical ...
Krysta-Lynn Amezcua   +6 more
doaj   +1 more source

Multifunctional Gold Nanocluster‐Based PROTAC System for Targeted Degradation of Phosphorylated Tau and Modulation of Neuroinflammation in Alzheimer's Disease

open access: yesAdvanced Functional Materials, EarlyView.
We present a novel proteolysis‐targeting chimera (PROTAC) system conjugated to lipoic acid gold nanoclusters (PLANC), designed to degrade pTau, regulate inflammatory signaling, and effectively traverse the blood‐brain barrier (BBB). PLANC degraded pTau at various phosphorylation sites, with mechanistic studies confirming proteasome‐mediated degradation
Sarah Nevins   +9 more
wiley   +1 more source

Directional Flow of Confined Polaritons in CrSBr

open access: yesAdvanced Materials, EarlyView.
CrSBr, a layered magnetic semiconductor, naturally channels self‐hybridized excitonpolaritons into highly directional flow. Its intrinsic optical anisotropy, high refractive index, and strong lightmatter coupling enable long‐range guided modes along the a‐axis, with propagation lengths set by their excitonphoton admixture.
Pratap Chandra Adak   +10 more
wiley   +1 more source

Analysis of related risk factors, treatment and prognosis of venous sinus thrombosis after surgery for cerebellopontine angle tumors

open access: yesInterdisciplinary Neurosurgery
Objective: Analyze independent risk factors for cerebral venous sinus thrombosis (CVST) following surgery for tumors in the cerebellopontine angle (CPA) region, construct and validate predictive models, and explore the prognosis of postoperative CVST ...
Yifan Zhou   +5 more
doaj   +1 more source

Suicide by firearm in Switzerland: who uses the army weapon? Results from the national survey between 2000 and 2010

open access: yesSwiss Medical Weekly, 2018
AIMS In comparison with other central European countries, Switzerland has a high prevalence of gun ownership and a high rate of suicide by shooting.
Nina Thoeni   +3 more
doaj   +1 more source

Tailoring Phonon‐Driven Responses in α‐MoO3 through Isotopic Enrichment

open access: yesAdvanced Materials, EarlyView.
ABSTRACT The implementation of polaritonic materials into nanoscale devices requires selective tuning of parameters to realize desired spectral or thermal responses. One robust material, α‐MoO3, an orthorhombic crystal boasting three distinct phonon dispersions, provides three polaritonic dispersions of hyperbolic phonon polaritons (HPhPs) across the ...
Thiago S. Arnaud   +31 more
wiley   +1 more source

Treatment of thoracolumbar fractures with severe collapse of the anterior and middle columns via balloon-assisted endplate reduction, transpedicular bone grafting and pedicle screw fixation

open access: yesJournal of Orthopaedic Surgery and Research
Purpose Thoracolumbar fractures involving severe collapse of the anterior and middle columns are difficult to reduce via posterior surgery. Therefore, we evaluated the effectiveness of balloon-assisted endplate reduction (BAER), transpedicular bone ...
Hai-qiang Shen   +8 more
doaj   +1 more source

Multimodal Locomotion in Insect‐Inspired Microrobots: A Review of Strategies for Aerial, Surface, Aquatic, and Interfacial Motion

open access: yesAdvanced Robotics Research, EarlyView.
This review identifies key design considerations for insect‐inspired microrobots capable of multimodal locomotion. To draw inspiration, biological and robotic strategies for moving in air, on water surfaces, and underwater are examined, along with approaches for crossing the air–water interface.
Mija Jovchevska   +2 more
wiley   +1 more source

Enhanced Glycolysis‐Driven Histone H3K18 Lactylation Regulates Epileptogenesis by Modulating the E3 Ubiquitin Ligase COP1

open access: yesAdvanced Science, EarlyView.
Neuronal PKM2‐driven glycolysis generates excess lactate that triggers histone H3K18 lactylation (H3K18la), establishing a pathogenic metabolic‐epigenetic axis in epilepsy. Elevated H3K18la enriches the Cop1 promoter, transcriptionally upregulating the E3 ubiquitin ligase COP1, which subsequently drives proteasomal degradation of GABAARβ2 and impairs ...
Yuan Meng   +8 more
wiley   +1 more source

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