Results 101 to 110 of about 58,906 (283)

Intelligent nano‐platforms in breast cancer therapy: Current advances and future perspectives

Precision Medical Sciences, EarlyView.
The smart nano platform in breast cancer treatment is designed with advanced nanocarriers, including liposomes, hydrogels, porous nanoparticles, and aptamer‐based systems. These systems are capable of targeted drug release and response to environmental stimuli.
Tina Rahimi, Moluk Aivazi
wiley   +1 more source

The effect of oral contraceptives on aromatase and Cox-2 expression in the endometrium of patients with idiopathic menorrhagia or adenomyosis [PDF]

, 2013
Hugo Maia Jr,1–3 Clarice Haddad,3 Nathaniel Pinheiro,4 Julio Casoy31School of Medicine, Federal University of Bahia, Salvador, Bahia, Brazil; 2Itaigara Memorial Day Hospital, Salvador, Bahia, Brazil; 3CEPARH (Centro de Pesquisas e Assistência
Pinheiro N, Casoy J, Maia H Jr, Haddad C
core  

Peripubertal aromatase inhibition in male rats has adverse long-term effects on bone strength and growth and induces prostatic hyperplasia [PDF]

, 2010
*This article is free to read on the publisher's website*\ud \ud Aromatase inhibitors have been increasingly used in boys with growth retardation to prolong the duration of growth and increase final height.
George A Werther, Peter J Simm, Risbridger, Gail, John D Wark, Gail P Risbridger, Simm, Peter, Vincenzo C Russo, Bajpai, Anurag, Werther, George, Stephen J McPherson, Azar, Walid, Russo, Vincenzo, McPherson, Stephen, Anurag Bajpai, Walid J Azar, Wark, John   +15 more
core   +1 more source

Molecular and genomic advances in breast cancer: A comprehensive review of predictive and therapeutic innovations

Precision Medical Sciences, EarlyView.
Breast cancer subtypes, estrogen receptor‐positive (ER+), HER2‐enriched, and TNBC, are defined by genomic and epigenetic signatures. Multi‐omics profiling, immunotherapy, liquid biopsy, and AI‐driven radiogenomics enable precision medicine. Tools like Oncotype DX and PAM50 support personalized care.
Samina Malik, Arif Malik, Shahzad Ahmad, Hassan Mohsin, Shazia Iqbal   +4 more
wiley   +1 more source

Investigation of aromatase inhibitory activity of metal complexes of 8-hydroxyquinoline and uracil derivatives [PDF]

, 2014
Veda Prachayasittikul,1 Ratchanok Pingaew,2 Chanin Nantasenamat,3 Supaluk Prachayasittikul,3 Somsak Ruchirawat,4,5 Virapong Prachayasittikul1 1Department of Clinical Microbiology and Applied Technology, Faculty of Medical Technology, Mahidol University ...
Prachayasittikul V, Pingaew R, Prachayasittikul S, Nantasenamat C, Ruchirawat S   +4 more
core  

Treatment with an aromatase inhibitor suppresses high-temperature feminization of genetic male (YY) Nile tilapia [PDF]

, 2002
High temperature (36° C) treatment during sexual differentiation caused significant changes in sex ratio in YY male Nile tilapia Oreochromis niloticus fry (64.5% males compared to 100.0% males at 28° C), while dietary treatment with a chemical ...
Penman, David, Kwon, Joon Yeong, McAndrew, Brendan   +2 more
core   +1 more source

Endocrine therapy‐induced cancer‐related fatigue in hormone‐dependent malignancies: Mechanisms, impact, and management strategies

Precision Medical Sciences, EarlyView.
Multipathway schematic of endocrine therapy–induced cancer‐related fatigue. Endocrine interventions trigger four interacting mechanisms—neuroendocrine dysregulation, systemic inflammation, energy‐metabolic failure, and psycho‐behavioral amplification—that culminate in the multidimensional CRF phenotype.
Jiajing Jiang, Jun Lu, Sen Qin, Ruzhou Chen, Qiuchen Zhang, Lvqi He, Yubei Li, Jingyao Yan   +7 more
wiley   +1 more source

Neural stem cell sex dimorphism in aromatase (CYP19) expression: a basis for differential neural fate [PDF]

, 2010
Jay Waldron1, Althea McCourty1, Laurent Lecanu1,21The Research Institute of the McGill University Health Centre, Montreal, Canada; 2Department of Medicine, McGill University, Quebec, CanadaPurpose: Neural stem cell (NSC) transplantation and pharmacologic
Althea McCourty, Laurent Lecanu, Jay Waldron   +2 more
core  

Aromatase in zebrafish: A potential target for endocrine disrupting chemicals. [PDF]

, 2006
In zebrafish, two isoforms of the aromatase gene exist, namely cyp19a1 and cyp19a2, expressed predominantly in the gonads and brain, respectively. In this study, we focus on characterizing the specificity of antibodies against the aromatase isoforms, and
Eggen, Rik, Segner, Helmut, Neuhauss, Stephan, Eggen, R, Neuhauss, S C F; https://orcid.org/, Alberti, M, Alberti, Martin, Kausch, Ulf, Kallivretaki, E, Kausch, U, Segner, H, Kallivretaki, Evangelina   +11 more
core   +1 more source

Assessment of Oxidative Stress, Vitellogenin, and Human Health Risks Derived From Nile Tilapia Exposed to Metals and Metalloids in Southeastern Brazil

Environmental Toxicology, EarlyView.
ABSTRACT Urban coastal lagoons are highly vulnerable ecosystems increasingly affected by metal contamination, as well as multiple anthropogenic stressors. This study evaluated ecotoxicological and human health risks associated with chronic metal exposure in Nile tilapia (Oreochromis niloticus) from an anthropogenically impacted lagoon in southeastern ...
Julia Araújo Alves, Priscila M. O. Muniz Cunha, Shênia Patrícia Corrêa Novo, Lorena Oliveira Souza Soares, Tatiana Dillenburg Saint‐Pierre, Fábio Veríssimo Correia, André Luís de Sá Salomão, Rachel Ann Hauser‐Davis, Enrico Mendes Saggioro   +8 more
wiley   +1 more source