Results 81 to 90 of about 58,906 (283)
Correlation between aromatase expression in the eutopic endometrium of symptomatic patients and the presence of endometriosis [PDF]
, 2012 Hugo Maia Jr1,2, Clarice Haddad1,2, Julio Casoy11CEPARH, 2Itaigara Memorial Day Hospital, Salvador, Bahia, BrazilObjective: To investigate whether aromatase expression in the eutopic endometrium correlates with the presence and severity of endometriosis ...
Maia Jr H, Casoy J, Haddad C
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Dual Aromatase−Steroid Sulfatase Inhibitors [PDF]
, 2016 By introducting the steroid sulfatase inhibitory pharmacophore into aromatase inhibitor 1 (YM511), two series of single agent dual aromatase−sulfatase inhibitors (DASIs) were generated. The best DASIs in vitro (JEG-3 cells) are 5, (IC50(aromatase) = 0.82
Christian Bubert (2225098) +8 more
core +1 more source
International Journal of Gynecology &Obstetrics, EarlyView.Abstract Objective This study evaluates the association between obesity and the presence of bowel endometriosis in patients undergoing surgery. Methods A retrospective cross‐sectional observational study was conducted with patients treated between September 2023 and December 2024, at a specialized endometriosis outpatient clinic of a tertiary hospital ...
Tereza Carolina Fonseca Corrêa +1 more
wiley +1 more source
Metabolic effects of aromatase inhibition [PDF]
, 2015 Aromatase, a member of the cytochrome P450 superfamily, catalyses the conversion of androgens to estrogens; specifically, testosterone to estradiol and androstenedione to estrone. Aromatase is widely expressed across a range of tissues and deleterious
Gibb, Fraser Wilson
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Aromatase expression in the normal human adult adrenal and in adrenocortical tumors: biochemical, immunohistochemical, and molecular studies [PDF]
, 2009 International audienceObjective: The aromatase enzyme catalyzes the final stage of estrogen biosynthesis pathway from androgens. Its expression in the adrenal is poorly Studied except for the rare estrogen-producing adrenocortical tumors.
Mittre, Hervé +6 more
core +1 more source
International Journal of Gynecology &Obstetrics, EarlyView.Abstract Objective To compare the efficacy of the levonorgestrel‐releasing intrauterine system combined with metformin versus oral progestin combined with metformin in fertility‐preserving treatment for patients with atypical endometrial hyperplasia and early endometrial cancer, and to analyze related factors affecting efficacy.
Pengpeng Gu +5 more
wiley +1 more source
Managing arthralgia in a postmenopausal woman taking an aromatase inhibitor for hormone-sensitive early breast cancer: a case study [PDF]
, 2012 Jane Bryce1, Martina Bauer2, Peyman Hadji21National Cancer Institute, Naples, Italy; 2Philipps University of Marburg, Marburg, GermanyBackground: In order to reduce the risk of recurrence, adjuvant treatment with an aromatase inhibitor (AI) is ...
Bauer M, Hadji P, Bryce J
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Journal of Applied Toxicology, EarlyView.ABSTRACT Bisphenol A (BPA) is a widely used industrial chemical found in polycarbonate plastics and epoxy resins and is recognized for its endocrine‐disrupting properties. Human exposure is common due to its presence in food packaging and everyday products. As BPA use has been restricted, structurally similar compounds such as BPS, BPB, BPAF, and BADGE
Nurbanu Zengin +4 more
wiley +1 more source
Neuroendocrine Transduction of Social Cues in the Bluehead Wrasse, Thalassoma bifasciatum [PDF]
, 2007 Understanding behavioral adaptations to changing social conditions is a key challenge for social neuroscience. The bluehead wrasse, Thalassoma bifasciatum, is a protogynous sex-changing fish with sex and role change under social control, making it an ...
Marsh, Kristen Erica
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Journal of Surgical Oncology, EarlyView.ABSTRACT Background Treatment guidelines recommending omission of axillary surgery in breast cancer are largely based on the SOUND and INSEMA trials. However, the extent to which their study populations represent real‐world patients remains unclear.
Tia Puiras +2 more
wiley +1 more source