Results 61 to 70 of about 58,906 (283)
Effects of ethanol or ethylene glycol exposure on PPARγ and aromatase expression in adipose tissue
Biochemistry and Biophysics ReportsThe estrogen-synthesizing enzyme aromatase is expressed in adipose tissue where it controls the local concentration of estrogen. It has been suggested that the organic solvents ethanol and ethylene glycol can induce estrogen synthesis by inhibiting PPARγ
Jacob Ardenkjær-Skinnerup +9 more
doaj +1 more source
Estradiol and the Development of the Cerebral Cortex: An Unexpected Role?
Frontiers in Neuroscience, 2018 The cerebral cortex undergoes rapid folding in an “inside-outside” manner during embryonic development resulting in the establishment of six discrete cortical layers.
Matthew C. S. Denley +4 more
doaj +1 more source
Aromatase Inhibitors for Endometriosis-Associated Infertility; Do We Have Sufficient Evidence? [PDF]
International Journal of Fertility and Sterility, 2016 Orally active aromatase inhibitors (AIs) have gained attention for treatment of infertile women with endometriosis in whom aromatase p450 is aberrantly expressed.
Hatem Abu Hashim
doaj +1 more source
Animal Research and One Health, EarlyView.This study delineates the early sex differentiation timeline in the northern snakehead (Channa argus). These findings provide a foundation for future sex‐control breeding in this economically important species. ABSTRACT The northern snakehead (Channa argus) is an economically important aquaculture species in China.
Chaonan Sun +6 more
wiley +1 more source
Cloning, sequencing and In situ localisation of guppy brain aromatase, cyp19b [PDF]
Oestrogens are biosynthesised by cytochrome p450-aromatase (Cyp19). Brain oestrogens serve several important functions of which nerve protection, cell proliferation, nerve development and behaviour control are a few.
Hallgren, Stefan, +1 more
core +2 more sources
Follicle Stimulating Hormone in Cattle Breeding: Fundamentals, Innovations, and Scope
Animal Research and One Health, EarlyView.FSH is crucial in cattle reproduction, with exogenous administration enhancing breeding and embryo production. Recombinant FSH offers advantages over pituitary‐extracted variants, including fewer injections, reduced stress, and safer production. These innovations improve breeding efficiency, optimize reproductive outcomes, and contribute to sustainable
Muhammad Shahzad +7 more
wiley +1 more source
Animal Research and One Health, EarlyView.This review critically evaluates clotrimazole as a potential antifungal for finfish aquaculture, highlighting strong mechanistic and in vitro efficacy against aquatic mycoses alongside major gaps in in vivo evidence, toxicokinetics, residue safety, and environmental risk, outlining priorities for responsible therapeutic development and regulatory ...
Arya Sen +2 more
wiley +1 more source
Interactions of aromatase and seladin-1: A neurosteroidogenic and gender perspective
Translational Neuroscience, 2019 Aromatase and seladin-1 are enzymes that have major roles in estrogen synthesis and are important in both brain physiology and pathology. Aromatase is the key enzyme that catalyzes estrogen biosynthesis from androgen precursors and regulates the brain’s ...
Kelicen-Ugur Pelin +3 more
doaj +1 more source
Sex Differences in Estradiol Secretion by Trigeminal Brainstem Neurons
Frontiers in Integrative Neuroscience, 2019 Estrogen status is a significant risk factor in the development of temporomandibular joint disorders (TMD). Classically, estrogen status is thought to derive mainly from ovarian sources; however, it is well known that estradiol (E2) also is synthesized ...
David A. Bereiter +2 more
doaj +1 more source
Clinical utilities of aromatase inhibitors in breast cancer [PDF]
, 2015 Saranya Chumsri Department of Hematology and Oncology, Mayo Clinic, Jacksonville, FL, USA Abstract: Aromatase is an enzyme that converts testosterones to estrogens.
Chumsri S
core