Results 91 to 100 of about 58,906 (283)
Local estrogen formation and its regulation in endometriosis
Reproductive Medicine and Biology, 2019 Background It has been well established that endometriosis is an estrogen‐dependent disease. Although the exact pathogenesis of the disease is still unclear, it is known to be characterized by estrogen‐dependent growth and maintenance of the ectopic ...
Taisuke Mori +7 more
doaj +1 more source
Aromatase inhibitor strategies in metastatic breast cancer [PDF]
, 2009 Heather L McArthur, Patrick G MorrisBreast Cancer Medicine Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY, USAAbstract: Despite ongoing therapeutic innovations, metastatic breast cancer (MBC) remains a treatable but
Patrick G Morris, Heather L McArthur
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Post‐Radiation Granuloma Annulare: A Series of Three Cases
JEADV Clinical Practice, EarlyView.ABSTRACT We report typical cases of biopsy confirmed granuloma annulare occurring on irradiated skin in the context of breast cancer in three women in their seventies. The lesions appeared immediately after start of irradiation in one patient, 4 and 15 months after the end of radiation treatment in the other two. The lesions eventually spread elsewhere
Léa Scheid, Mona Mitcov, Dan Lipsker
wiley +1 more source
Design, synthesis and biological evaluation of Exemestane derivatives as potent inhibitors of Aromatase [PDF]
, 2019 Aromatase is a member of the cytochrome P450 superfamily, responsible for a key step in the biosynthesis of estrogens, allowing the aromatization of androgens into estrogens.
Alcaro S +6 more
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Clinical importance of intratumoral aromatase [PDF]
, 1998 Evidence to support the contention that estrogen biosynthesis in breast cancers is of clinical significance has been sought by relating activity to (i) clinical response to aromatase inhibitors and (ii) tumor concentrations of estrogens.
Telford, J +3 more
core +1 more source
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Endometrial cancer (EC) is closely related to metabolic disorders. We aimed to investigate whether preoperative dyslipidemia independently affects the prognosis of patients with EC. One hundred and ninety‐four women diagnosed with EC by pathology and who had undergone standardized surgical treatment at the Affiliated Hospital of Jining Medical
Song Li +5 more
wiley +1 more source
Ectopic expression of aromatase in embryonic gonads. [PDF]
, 2013 RCASBP-Aromatase virus was injected into blastoderms and aromatase expression was assessed at embryonic day 10.5 by immunostaining (10×magnification). For each, the left (Lg) and right (Rg) gonads are shown with aromatase staining (green).
David M. Cummins (428224) +4 more
core +1 more source
Obesity, EarlyView.ABSTRACT Objective This study aimed to evaluate the association of glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) with risks of osteoporosis, major osteoporotic fractures, and degenerative musculoskeletal disorders in nondiabetic adults with obesity compared with other obesity medications.
Jie‐Syuan Wu +5 more
wiley +1 more source
Screening 2‒mercaptoimidazole derivatives for breast cancer treatment
Tạp chí Khoa học và Công nghệ, 2023 2‒Mecaptoimidazole (2MC), its tautomer (2MI), and derivatives were evaluated in silico for their antioxidant activity and potential for breast cancer drug development.
Tran Viet Anh +4 more
doaj
Effects of Ovarian Theca Cells on Granulosa Cell Differentiation During Gonadotropin-Independent Follicular Growth in Cattle [PDF]
, 2006 We investigated the effects of theca cells or FSH on granulosa cell differentiation and steroid production during bovine early follicular growth, using a co-culture system in which granulosa and theca cells were cultured on opposite sides of a collagen ...
Shukunami, Ken-ichi +6 more
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