Results 101 to 110 of about 30,153 (204)

Exemestane, a new steroidal aromatase inhibitor of clinical relevance

open access: yes, 2002
Breast cancer is the leading cause of death among women and the contribution of circulating oestrogens to the growth of some mammary tumours has been recognized.
Lombardi, Paolo
core   +1 more source

Virtual Screening of Apigenin and Luteolin as Natural Aromatase Inhibitors for the Treatment of Breast Cancer Patients

open access: yesIraqi Journal of Industrial Research
Aromatase is an enzyme that converts androgens (like testosterone) to estrogens (like 17- estradiol). It is also a highly successful therapeutic target for endocrine-responsive breast cancer.
Baydaa Hamad Obaid Saleh
doaj   +1 more source

A Case for the Use of Combined Hormonal Therapy for Aggressive Angiomyxoma: Complete Response to Goserelin and Letrozole Following Incomplete Surgical Resection

open access: yesClinical Case Reports
We report on the use of combined hormonal therapy with a gonadotropin releasing hormone antagonist and aromatase inhibitor in pelvic aggressive angiomyxoma, with a complete response.
George Mallat   +4 more
doaj   +1 more source

EFEKTIFITAS AROMATASE INHIBITOR YANG DIBERIKAN MELALUI PAKAN BUATAN TERHADAP SEX REVERSAL IKAN NILA MERAH Oreochromis sp.

open access: yes, 2018
Red tilapia, Oreochromis sp. is a popular fishery commodity because of the advantages such as easy at reproduction, fast growth and has a great taste.
LIANA, YENNI PANCA
core  

Open-label Phase II study of everolimus plus endocrine therapy in postmenopausal women with ER-positive and HER2-negative metastatic breast cancer (Chloe trial)

open access: yesOpen Access Journal of Clinical Trials, 2018
Tatsunori Shimoi,1 Akihiko Shimomura,1 Tadahiko Shien,2 Yukari Uemura,3 Hiroaki Kato,4 Masahiro Kitada,5 Tatsuya Toyama,6 Tomohiko Aihara,7 Hirofumi Mukai8 1Department of Breast and Medical Oncology, National Cancer Center Hospital, Tokyo, Japan ...
Shimoi T   +8 more
doaj  

Inhibitors of oestrogen biosynthesis: preclinical studies with CGS 16949A, a new nonsteroidal aromatase inhibitor

open access: yes, 2017
Inhibitors of the aromatase enzyme represent a class of therapeutic agents which potently inhibit oestrogen biosynthesis in vivo. This inhibition of oestrogen biosynthesis is well established as effective therapy in the treatment of oestrogen-dependent ...
Schieweck, Klaus   +4 more
core  

[Growth rate can be manipulated. Estrogen production in pubertal boys can be blocked by an aromatase inhibitor]

open access: yes, 2002
A review of a twelve month clinical trial [1] using a new, effective aromatase inhibitor treatment in boys with delayed puberty shows that the pubertal increase in estrogen levels can be blocked, with concomitant preserved pubertal growth rate ...
Hagenäs, L,
core  

Real-world effectiveness of palbociclib in combination with an aromatase inhibitor in HR+/HER2- bone-only metastatic breast cancer. [PDF]

open access: yesBreast
Brufsky A   +9 more
europepmc   +1 more source

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