Results 81 to 90 of about 665,294 (217)

Assessment and management of dyspareunia in peri‐ and postmenopausal women: A phenotype‐based gynecologic approach

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Dyspareunia in peri‐ and postmenopausal women is common, clinically consequential, and often undertreated in gynecologic practice. Although genitourinary syndrome of menopause (GSM) is a frequent contributor, intercourse‐related pain may also reflect vestibular, pelvic floor, dermatologic, inflammatory, treatment‐related, and psychosocial ...
Marek Broul, Marcel Vančo, Jaroslava Banýrová, Aneta Hujová   +3 more
wiley   +1 more source

Effectiveness of bisphosphonate combined with activated vitamin D in patients with aromatase inhibitor-induced osteoporosis after breast cancer operation

Osteoporosis and Sarcopenia, 2018
Objectives: We compared the effectiveness of bisphosphonates combined with activated vitamin D administered for therapy of aromatase inhibitor-induced osteoporosis after a breast cancer operation and primary postmenopausal osteoporosis through propensity
Mizue Tanaka, Soichiro Itoh, Yasuhiro Takeuchi   +2 more
doaj   +1 more source

Brain Aromatase in the guppy, Poecilia reticulata [Elektronisk resurs] : Distribution, control and role in behaviour

, 2009
Oestrogens are produced by aromatisation of androgens by the aromatase enzyme. In the vertebrate brain this synthesis has vital functions in nerve protection, cell proliferation and nerve development during injury respectively brain development.
Olsén, Håkan,, Borg, Bertil,, Hallgren, Stefan,, Bakker, Julie,   +3 more
core  

Conserved SERPINE2 function maintains ovarian estrogen production to support fertility in goats and mice

iMetaOmics, EarlyView.
Single‐nucleus RNA sequencing and functional profiling of goat ovaries with divergent litter sizes revealed prolificacy‐associated granulosa cell (GC) states characterized by enhanced proliferation‐ and steroidogenesis‐related features, together with altered predicted cell–cell communication.
Sanbao Zhang, Yirong Wei, Xiaoping Guo, Ruimen Zhang, Yingming Wei, Yanna Huang, Qinyang Jiang   +6 more
wiley   +1 more source

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source

Epiretinal membrane formation associated with letrozole therapy – Two case reports

Indian Journal of Ophthalmology. Case Reports
Letrozole, an aromatase inhibitor, is being increasingly used for adjuvant endocrine therapy in hormone-positive postmenopausal breast cancer. Although aromatase inhibitors are thought to increase vitreoretinal traction by causing estrogen reduction ...
Hridya Hareendran, R Unnikrishnan Nair, Manoj Soman, Varsha Vijayan   +3 more
doaj   +1 more source

Association Between Preoperative Dyslipidemia and the Prognosis of Patients With Endometrial Cancer: A Retrospective Cohort Study

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Endometrial cancer (EC) is closely related to metabolic disorders. We aimed to investigate whether preoperative dyslipidemia independently affects the prognosis of patients with EC. One hundred and ninety‐four women diagnosed with EC by pathology and who had undergone standardized surgical treatment at the Affiliated Hospital of Jining Medical
Song Li, Rong‐He Sun, Qing Chen, Zeng‐Shu Huang, Yun‐Fei Wang, Chang‐Zhong Li   +5 more
wiley   +1 more source

Vaginal Laser Treatment for Genitourinary Syndrome of the Menopause: A Dose‐Determining Study in Breast Cancer Survivors

Lasers in Surgery and Medicine, EarlyView.
ABSTRACT Objectives Breast cancer survivors (BCSs) receiving endocrine therapy frequently develop genitourinary syndrome of menopause, characterized by vaginal dryness, pain, and urinary symptoms. Fractional CO2 vaginal laser therapy has been proposed as a non‐hormonal management option, but the optimal number of treatment sessions remains unclear.
Sine Jacobsen, Marianne Glavind‐Kristensen, Anders Bonde Jensen, Axel Forman, Vibe Munk Bertelsen, Pinar Bor   +5 more
wiley   +1 more source

Prevention of Early Onset of Breast Cancer With Ashwagandha

Molecular Carcinogenesis, EarlyView.
ABSTRACT Prevention of breast cancer is feasible because many risk factors for this malignancy are known (e.g., family history, reproductive factors, etc.). Medicinal plants and/or their bioactive phytochemicals are attractive for the prevention of early onset of breast cancer due to their generally favorable safety profile.
Eun‐Ryeong Hahm, Su‐Hyeong Kim, Shivendra V. Singh   +2 more
wiley   +1 more source

Capivasertib After Progression on CDK4/6 Inhibitor Combined with Endocrine Therapy in a Patient with HR-Positive, HER2-Negative Metastatic Breast Cancer: A Case Report

healthbook TIMES. Oncology Hematology
Capivasertib, an AKT inhibitor, combined with fulvestrant, has demonstrated significantly improved progression-free survival compared with fulvestrant alone in patients with hormone receptor (HR)-positive advanced breast cancer whose disease progressed ...
Diana Chiru, Marcus Vetter
doaj   +1 more source