Results 111 to 120 of about 24,588 (216)

Can acromegaly be controlled in all cases?

Journal of Neuroendocrinology, Volume 38, Issue 8, August 2026.
Abstract Acromegaly is a rare disease, due in most of the cases to a growth hormone (GH)‐secreting pituitary adenoma (PA), namely neuroendocrine tumour (PitNET). The treatment of patients with acromegaly is multimodal and multi‐step, including surgery, medical therapies, and radiotherapy.
Sabrina Chiloiro, Francesco Padovano Sorrentino, Alessandra Vicari, Antonella Giampietro, Pier Paolo Mattogno, Quintino Giorgio D'Alessandris, Rosalinda Calandrelli, Tommaso Tartaglione, Marco Gessi, Simona Gaudino, Laura De Marinis, Guido Rindi, Francesco Doglietto, Antonio Bianchi, Alfredo Pontecorvi   +14 more
wiley   +1 more source

Pancreatic cancer cachexia promotes cardiac dysfunction through altered adrenergic signalling in the heart

The Journal of Physiology, Volume 604, Issue 15, Page 6281-6301, 1 August 2026.
Abstract figure legend The β1‐adrenergic receptor is the predominant adrenergic subtype expressed on cardiac myocytes. Upon stimulation it activates downstream signalling pathways that increase the heart rate and cardiac output to meet metabolic demands.
Parham Diba, Peter R. Levasseur, Samuel D. Newton, Khia Min Sabrina Koh, Paige C. Arneson‐Wissink, Xinxia Zhu, Peter Pham, Heike Mendez, Luke Whitcomb, Ariana Sattler, William R Woodward, Beth A. Habecker, Daniel L. Marks, Aaron J. Grossberg   +13 more
wiley   +1 more source

Arrestin-g pain [PDF]

Nature Chemical Biology, 2019
openaire   +2 more sources

Altered Intracellular Trafficking as a Mechanism for Prolonged Duration of G Protein-Coupled Receptor Activation. [PDF]

J Am Chem Soc
Kim TW, Gerrard EJ, Shin J, Gardella TJ, Wootten D, Sexton PM, Cary BP, Gellman SH.   +7 more
europepmc   +1 more source

Dynamic Pathway Selectivity of TAS2R5 toward or Away from β-Arrestin or G Protein from Biased Agonists. [PDF]

Biochemistry
Kim D, Strzelinski HR, Longabardi CM, Liggett SB.   +3 more
europepmc   +1 more source

Editorial: G Protein-Coupled Receptor Kinases (GRKs) and β-Arrestins: New Insights Into Disease Regulators

Frontiers in Pharmacology, 2020
Yuichi Hattori, Martin C. Michel
doaj   +1 more source

Intrinsic conformational equilibria position arrestin-2 for activation. [PDF]

Protein Sci
Shriver TJ, Kahraman K, Pan M, Dağ Ç, Tonelli M, Robson SA, Ziarek JJ.   +6 more
europepmc   +1 more source

Structure-Activity Relationships and Ligand-Dependent Arrestin Bias in μ-Opioid Receptor-Mediated ERK Activation. [PDF]

Biomol Ther (Seoul)
Huang L, Wang M, Kundu D, Paudel S, Peng L, Xian X, Jang CG, Kim KM.   +7 more
europepmc   +1 more source

Is the arrestin of a primitive chordates, ascidian a common ancestor of vertebrate visual arrestin and β-arrestin?

Seibutsu Butsuri, 2001
M. Nakagawa, H. Orii, T. Horie, R. Yoshida, M. Tsuda   +4 more
openaire   +1 more source

PAR2-β-arrestin 2-ERK axis mediates <i>Malassezia globosa</i>-induced IL-17 response by disrupting ZO-1 in keratinocytes. [PDF]

iScience
Tang J, Li F, Hong J, Li X, Zhou Y, Liu J, Fan Y.   +6 more
europepmc   +1 more source