Results 91 to 100 of about 178,362 (241)

Morphine Attenuated the Cytotoxicity Induced by Arsenic Trioxide in H9c2 Cardiomyocytes. [PDF]

open access: yes, 2016
Arsenic trioxide (ATO) is an efficient drug for the treatment of the patients with acute promyelocytic leukemia (APL). Inhibition of proliferation as well as apoptosis, attenuation of migration, and induction of differentiation in tumor cells are the ...
Amini-Khoei, Hossein.   +10 more
core  

Management of elderly patients with acute promyelocytic leukemia: progress and problems [PDF]

open access: yes, 2013
Despite substantial progress in the management and outcome of acute promyelocytic leukemia (APL) during the last decades, older age remains a prominent negative prognostic factor.
Eva Lengfelder   +2 more
core   +1 more source

Beyond Cisplatin: Combination Therapy with Arsenic Trioxide.

open access: yesInorganica Chimica Acta, 2019
Platinum drugs (cisplatin, oxaliplatin, and carboplatin) and arsenic trioxide are the only commercial inorganic non-radioactive anticancer drugs approved by the US Food and Drug Administration.
Ðenana Miodragović   +4 more
semanticscholar   +1 more source

Mixed‐Oxide Nanostructure‐Based Electrochemical Sensors for Environmental Pollutants

open access: yesAnalysis &Sensing, Volume 6, Issue 2, March 2026.
This review discusses the development of mixed‐oxide electrochemical sensors for detecting environmental pollutants, covering various work electrodes, combinations of nanomaterials for enhanced sensing, and real‐world diagnostic applications. Emerging environmental pollutants pose increasing risks to ecosystems and human health, creating a demand for ...
Cavour M. Neto   +9 more
wiley   +1 more source

Pre-application of arsenic trioxide may potentiate cytotoxic effects of vinorelbine/docetaxel on neuroblastoma SK-N-SH cells.

open access: yesBiomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2019
BACKGROUND Arsenic trioxide is effective in the treatment of acute promyelocytic leukemia and is currently in use in clinical trials for the treatment of solid tumor types.
K. Qi   +6 more
semanticscholar   +1 more source

Unraveling the role of TP53 mutations in myeloproliferative neoplasms: Molecular mechanisms of leukemic transformation

open access: yesHemaSphere, Volume 10, Issue 3, March 2026.
Abstract TP53 mutations are found in over 50% of tumor types, including myeloproliferative neoplasms (MPNs). MPNs are characterized by a chronic phase, which may progress to secondary acute myeloid leukemia (sAML). Here, we discuss the physiological functions of p53 in hematopoiesis and its deregulation in MPNs.
Suzana da Silva‐Benedito   +6 more
wiley   +1 more source

Cardiovascular effects of arsenic: clinical and epidemiological findings [PDF]

open access: yes, 2013
Several population studies relate exposure to high levels of arsenic with an increased incidence of ischemic heart disease and cardiovascular mortality.
Bianchi, Fabrizio   +3 more
core   +1 more source

The Application of Arsenic Trioxide in Ameliorating ABT-737 Target Therapy on Uterine Cervical Cancer Cells through Unique Pathways in Cell Death

open access: yesCancers, 2019
ABT-737, a B cell lymphoma-2 (Bcl-2) family inhibitor, activates apoptosis in cancer cells. Arsenic trioxide is an apoptosis activator that impairs cancer cell survival. The aim of this study was to evaluate the effect of a combination treatment with ABT-
I-Lun Hsin   +4 more
semanticscholar   +1 more source

An Updated Narrative Review on the Therapeutic Potential of Resveratrol in the Treatment of Cancer

open access: yesHealth Science Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Background Cancer is a significant global health challenge, affecting millions of people every year. Overall survival rates have improved over time, but some patients exhibit treatment resistance, prompting ongoing research to find suitable and effective sensitizers.
Mohammad Ashraful Islam   +6 more
wiley   +1 more source

Rapid Reduction in Breast Cancer Mortality With Inorganic Arsenic in Drinking Water

open access: yesEBioMedicine, 2014
Background: Arsenic trioxide is effective in treating promyelocytic leukemia, and laboratory studies demonstrate that arsenic trioxide causes apoptosis of human breast cancer cells.
Allan H. Smith   +10 more
doaj   +1 more source

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