Results 81 to 90 of about 178,362 (241)
ABSTRACT Hematologic emergencies are urgent health conditions which result in significant mortality and morbidity unless timely therapeutic measures are taken. Therapeutic success depends on their timely and accurate recognition by hematology laboratory services.
Ganna Shestakova +2 more
wiley +1 more source
Epstein - Barr virus latent membrane protein 1 suppresses reporter activity through modulation of promyelocytic leukemia protein-nuclear bodies [PDF]
The Epstein-Barr virus (EBV) encoded Latent Membrane Protein 1 (LMP1) has been shown to increase the expression of promyelocytic leukemia protein (PML) and the immunofluorescent intensity of promyelocytic leukemia nuclear bodies (PML NBs).
Mark D Sides +5 more
core +1 more source
Phosphate Transporters Mediate the Uptake of Monothioarsenate
ABSTRACT Arsenic (As) is one of the most problematic environmental toxins. Exposure to As, predominantly via drinking water and the intake of food, represents a major human health threat. Various species of As exist in the environment, among them organic and inorganic thioarsenates.
Sebastian Haider +3 more
wiley +1 more source
Bortezomib and Arsenic Trioxide Activity on a Myelodysplastic Cell Line (P39): a Gene Expression Study [PDF]
L
Canesastraro, Martina +7 more
core +1 more source
Strategies using oral arsenic trioxide (As2O3) are efficacious in relapsed acute promyelocytic leukemia (APL), but they have not been examined in newly diagnosed cases.
H. Gill +18 more
semanticscholar +1 more source
The hidden regulators: Non‐coding RNAs in KMT2A‐rearranged acute lymphoblastic leukemia
Abstract Acute lymphoblastic leukemia (ALL) driven by KMT2A rearrangements (KMT2A‐r) is an aggressive hematologic malignancy with poor prognosis and a high incidence in infants. While KMT2A fusion proteins drive leukemogenesis through transcriptional dysregulation, recent discoveries have highlighted the pivotal role of non‐coding RNAs (ncRNAs) in ...
Maria Augusta Poersch +5 more
wiley +1 more source
Arsenic trioxide inhibits transforming growth factor-β1-induced fibroblast to myofibroblast differentiation in vitro and bleomycin induced lung fibrosis in vivo [PDF]
Background Idiopathic pulmonary fibrosis (IPF) is a progressive disease of insidious onset, and is responsible for up to 30,000 deaths per year in the U.S.
Lasky, Joseph A +6 more
core +3 more sources
Synergistic effect of arsenic trioxide, vismodegib and temozolomide on glioblastoma.
The treatment of glioblastoma is a critical health issue, owing to its resistance to chemotherapy. The current standard of treatment is surgical resection, followed by adjuvant radiotherapy and temozolomide treatment.
C. Bureta +8 more
semanticscholar +1 more source
Integration of epigenetics into ecotoxicology: insights and fundamental research needs
ABSTRACT Epigenetics refers to heritable changes in genome function that occur without direct alterations to the DNA sequence. A multitude of environmental contaminants can influence the epigenetic marks of a genome. Changes of epigenetic marks including DNA methylation, histone modifications, and non‐coding RNAs can induce alterations at the gene ...
Albano Pinto +3 more
wiley +1 more source
We report the clinical features and treatment outcome of 33 patients with multiple sclerosis who developed acute promyelocytic leukemia. Thirty patients were previously exposed to mitoxantrone.
Emanuele Ammatuna +9 more
doaj +1 more source

