Results 51 to 60 of about 5,753 (307)

Arsenic speciation in biomedical sciences: Recent advances and applications

Kaohsiung Journal of Medical Sciences, 2011
Speciation analysis of trace elements is an important issue in biomedical and toxicological sciences because different elemental species have different effects on health and the environment. For humans, arsenic (As) is a toxic element; the toxicity of As
Keng-Chang Hsu, Chien-Che Sun, Yeou-Lih Huang   +2 more
doaj   +1 more source

The functions of crucial cysteine residues in the arsenite methylation catalyzed by recombinant human arsenic (III) methyltransferase. [PDF]

PLoS ONE, 2014
Arsenic (III) methyltransferase (AS3MT) is a cysteine (Cys)-rich enzyme that catalyzes the biomethylation of arsenic. To investigate how these crucial Cys residues promote catalysis, we used matrix-assisted laser desorption ionization-time of flight-mass
Shuping Wang, Zhirong Geng, Nan Shi, Xiangli Li, Zhilin Wang   +4 more
doaj   +1 more source

Antitrypanosomal and Antileishmanial Activity of Chalcones and Flavanones from Polygonum salicifolium

Pathogens, 2021
Trypanosomiasis and leishmaniasis are a group of neglected parasitic diseases caused by several species of parasites belonging to the family Trypansomatida. The present study investigated the antitrypanosomal and antileishmanial activity of chalcones and
Ahmed M. Zheoat, Samya Alenezi, Ehab Kotb Elmahallawy, Marzuq A. Ungogo, Ali H. Alghamdi, David G. Watson, John O. Igoli, Alexander I. Gray, Harry P. de Koning, Valerie A. Ferro   +9 more
doaj   +1 more source

High‐Performance Violet Phosphorene‐Based Device via Tellurium Doping‐Induced Contact Resistance Reduction

Advanced Science, EarlyView.
Tellurium substitution for phosphorus in violet phosphorus significantly reduces contact resistance, enhancing FET performance under ambient conditions. ABSTRACT Two‐dimensional materials have attracted much attention in various research fields. The phosphorene structures with various allotropes, another type of elemental 2D materials after graphene ...
Zhuorui Wen, Xuewen Zhao, Wenju Zhou, Wenqi Mu, Rui Zhai, Jiazheng Lin, Xin Liu, Kerui Hu, Zhiqi Zhang, Guodong Meng, Yonghong Cheng, Huiyang Gou, Jinying Zhang   +12 more
wiley   +1 more source

New mechanisms of bacterial arsenic resistance

Biomedical Journal, 2016
Arsenic is the most pervasive environmental substance and is classified by the International Agency for Research on Cancer as a Group 1 human carcinogen.
Hung-Chi Yang, Barry P. Rosen
doaj   +1 more source

Preabsorptive Metabolism of Sodium Arsenate by Anaerobic Microbiota of Mouse Cecum Forms a Variety of Methylated and Thiolated Arsenicals

, 2016
The conventional scheme for arsenic methylation accounts for methylated oxyarsenical production but not for thioarsenical formation. Here, we report that in vitro anaerobic microbiota of mouse cecum converts arsenate into oxy- and thio- arsenicals ...
John T. Creed (2208040), David J. Thomas (23135), Michael J. Kohan (2208043), Tatyana S. Pinyayev (2208049), Karen Herbin-Davis (2208046)   +4 more
core   +1 more source

Organic Electrochemical Transistors for Neuromorphic Bioelectronics: Materials and Manufacturing Technologies

Advanced Science, EarlyView.
Organic electrochemical transistors bridge biological ionic signaling and neuromorphic computation through volumetric electrochemical gating. This review connects Organic mixed ionic–electronic conductor materials, device architectures, and manufacturing technologies to show how geometry, ion transport, and fabrication strategies program plasticity ...
Hyunjin Lee, Jihyang Park, Xinyi Wang, Yueqi Deng, Jiashu Ren, Tao Zhou   +5 more
wiley   +1 more source

High-throughput screening for the identification of dual inhibitors of BRD4 and RIPK3 toward the development of small-molecule medical countermeasure agents against arsenicals

SLAS Discovery
Warfare arsenicals are potent blistering agents and cause severe inflammation following their skin exposure. Data from our group (unpublished) show that these chemicals act by activating bromodomain-4 and RIPK signaling.
Marina Fosso Yatchang, Ling Zhai, Omar Moukha-Chafiq, Bini Mathew, Fuad Al Abir, Sixue Zhang, Pedro Ruiz, Sara McKellip, Miranda Nebane, Jake Y. Chen, Anupam Agarwal, James R. Bostwick, Mark J. Suto, Mohammad Athar, Corinne E. Augelli-Szafran   +14 more
doaj   +1 more source

Arsenic in Cancer Treatment: Challenges for Application of Realgar Nanoparticles (A Minireview)

Toxins, 2010
While intensive efforts have been made for the treatment of cancer, this disease is still the second leading cause of death in many countries. Metastatic breast cancer, late-stage colon cancer, malignant melanoma, multiple myeloma, and other forms of ...
Peter Baláž, Ján Sedlák
doaj   +1 more source

Identifying a panel of genes/proteins/miRNAs modulated by arsenicals in bladder, prostate, kidney cancers [PDF]

, 2018
Arsenic and arsenic-derivative compounds, named as arsenicals, represent a worldwide problem for their effect on the human health and, in particular, for their capability to increase the risk of developing cancer such as kidney, bladder and prostate ...
SILVIA MARCHESE, GENNARO CILIBERTO, SUSAN COSTANTINI, ANDREA POLO, GIUSEPPINA DE PETRO, MAURIZIO MONTELLA, ALFREDO BUDILLON   +6 more
core   +1 more source