Results 21 to 30 of about 12,135 (165)

Concomitant nevirapine impacts pharmacokinetic exposure to the antimalarial artemether-lumefantrine in African children.

PLoS ONE, 2017
BackgroundThe antiretroviral drug nevirapine and the antimalarial artemisinin-based combination therapy artemether-lumefantrine are commonly co-administered to treat malaria in the context of HIV.
Liusheng Huang, Vincent Carey, Jane C Lindsey, Florence Marzan, David Gingrich, Bobbie Graham, Linda Barlow-Mosha, Phionah K Ssemambo, Portia Kamthunzi, Sharon Nachman, Sunil Parikh, Francesca T Aweeka, IMPAACT P1079 protocol team   +12 more
doaj   +1 more source

Pyronaridine–artesunate and artemether–lumefantrine for the treatment of uncomplicated Plasmodium falciparum malaria in Kenyan children: a randomized controlled non-inferiority trial

Malaria Journal, 2018
Background Pyronaridine–artesunate is a novel artemisinin-based combination therapy. The efficacy and safety of pyronaridine–artesunate were compared with artemether–lumefantrine for the treatment of uncomplicated Plasmodium falciparum malaria in ...
Johanna M. Roth, Patrick Sawa, Nicodemus Makio, George Omweri, Victor Osoti, Selpha Okach, Felix Choy, Henk D. F. H. Schallig, Pètra Mens   +8 more
doaj   +1 more source

Artesunate + amodiaquine versus artemether-lumefantrine for the treatment of uncomplicated Plasmodium falciparum malaria in the Colombian Pacific region: a noninferiority trial

Revista da Sociedade Brasileira de Medicina Tropical, 2012
INTRODUCTION: In Colombia, there are no published studies for the treatment of uncomplicated Plasmodium falciparum malaria comparing artemisinin combination therapies.
Fernando De la Hoz Restrepo, Alexandra Porras Ramírez, Alejandro Rico Mendoza, Freddy Córdoba, Diana Patricia Rojas   +4 more
doaj   +1 more source

MOESM1 of Does artemetherâ lumefantrine administration affect mosquito olfactory behaviour and fitness?

, 2019
Additional file 1: Table S1. Pairwise comparison (LSD) of mosquito response to skin odour of eight participants in the olfactometer assay. Values in bold indicate significant differences.
de Boer, Jetske, Busula, Annette, ten Berge, Jet, van Dijk, Tessa, Takken, Willem   +4 more
openaire   +1 more source

Reduction of malaria transmission to Anopheles mosquitoes with a six-dose regimen of co-artemether. [PDF]

, 2005
BACKGROUND: Resistance of malaria parasites to chloroquine (CQ) and sulphadoxine-pyrimethamine (SP) is increasing in prevalence in Africa. Combination therapy can both improve treatment and provide important public health benefits if it curbs the spread ...
Neal Alexander (18417), Colin J Sutherland (18042), Christopher J Drakeley (58257), Rosalind Coleman (18415), Targett Geoffrey A. T, Sutherland Colin J, Gijs Walraven (18413), Jawara, Musa, Coleman, Rosalind, Sam Dunyo, Musa Jawara (18412), Alexander Neal, Geoffrey A T Targett, Sutherland, Colin J, Ord Rosalynn, Musa Jawara, Coleman Rosalind, Pinder Margaret, Jawara Musa, Ord, Rosalynn, Walraven, Gijs, Targett, Geoffrey AT, Rosalynn Ord (18410), Geoffrey A. T Targett (18418), Neal Alexander, Colin J Sutherland, Sam Dunyo (58256), Rosalind Coleman, Margaret Pinder (1712), Gijs Walraven, Walraven Gijs, Drakeley, Christopher J, Alexander, Neal, Margaret Pinder, Dunyo Sam, Dunyo, Sam, Rosalynn Ord, Christopher J Drakeley, Drakeley Christopher J, Pinder, Margaret   +39 more
core   +1 more source

MOESM2 of Absence of in vivo selection for K13 mutations after artemetherâ lumefantrine treatment in Uganda

, 2017
Additional file 2. List of primers and probes for multiplex and qPCR for SNP typing in Plasmodium falciparum.
Balikagala, Betty, Mita, Toshihiro, Ikeda, Mie, Sakurai, Miki, Shouki Yatsushiro, Takahashi, Nobuyuki, Shin-Ichiro Tachibana, Auma, Mary, Ntege, Edward, Ito, Daisuke, Takashima, Eizo, Nirianne Palacpac, Egwang, Thomas, Onen, Joseph, Kataoka, Masatoshi, Eisaku Kimura, Horii, Toshihiro, Tsuboi, Takafumi   +17 more
openaire   +1 more source

Artemether-lumefantrine versus dihydroartemisinin-piperaquine for treatment of malaria: a randomized trial. [PDF]

, 2007
OBJECTIVES: To compare the efficacy and safety of artemether-lumefantrine (AL) and dihydroartemisinin-piperaquine (DP) for treating uncomplicated falciparum malaria in Uganda. DESIGN: Randomized single-blinded clinical trial.
Staedke Sarah G, Yeka Adoke, Dorsey, Grant, Rwakimari John B, Nosten François, Talisuna, Ambrose O, Dorsey Grant, Greenhouse Bryan, Rosenthal Philip J, Lugemwa, Myers, Rosenthal, Philip J, Yeka, Adoke, Staedke, Sarah G, Greenhouse, Bryan, Rwakimari, John B, Bukirwa, Hasifa, Kamya Moses R, Lugemwa Myers, Kamya, Moses R, Bukirwa Hasifa, Wabwire-Mangen Fred, Talisuna Ambrose O, Wabwire-Mangen, Fred, Nosten, François   +23 more
core   +1 more source

Therapeutic failure after regimen with artemether-lumefantrine combination therapy: a report of three cases in Benin City, Nigeria

Revista da Sociedade Brasileira de Medicina Tropical, 2019
Artemisinin-based combination therapy (ACT) is recommended by the World Health Organization for the treatment of uncomplicated malaria. Currently, there appears to be a downward trend in the efficacy of ACT in some parts of sub-Saharan Africa because ...
Osamudiamen Ebohon, Francis Irabor, Linda Osahon Ebohon, Ehimwenma Sheena Omoregie   +3 more
doaj   +1 more source

MOESM1 of Absence of in vivo selection for K13 mutations after artemetherâ lumefantrine treatment in Uganda

, 2017
Additional file 1. Eligibility criteria for recruitment into the therapeutic efficacy study and the molecular study.
Balikagala, Betty, Mita, Toshihiro, Ikeda, Mie, Sakurai, Miki, Shouki Yatsushiro, Takahashi, Nobuyuki, Shin-Ichiro Tachibana, Auma, Mary, Ntege, Edward, Ito, Daisuke, Takashima, Eizo, Nirianne Palacpac, Egwang, Thomas, Onen, Joseph, Kataoka, Masatoshi, Eisaku Kimura, Horii, Toshihiro, Tsuboi, Takafumi   +17 more
openaire   +1 more source

Randomized trial of safety and effectiveness of chlorproguanil-dapsone and lumefantrine-artemether for uncomplicated malaria in children in the Gambia. [PDF]

, 2011
BACKGROUND: Chlorproguanil-dapsone (Lapdap), developed as a low-cost antimalarial, was withdrawn in 2008 after concerns about safety in G6PD deficient patients.
Njie, Fanta, Bisseye, C, Nwakanma, D, Snell, P., Walton, Robert T., Conway D., Nwakanma, Davis, Cyrille Bisseye, Joof F., Sesay, Sanie, Milligan P., Walton, R, Sanie Sesay, Snell Paul, Joof, F., Snell P., Cheung, Yin Bun, Milligan Paul, Sesay S., Sesay, S, Bisseye C., Diatta Mathurin, Bisseye, Cyrille, Njie, F, Dunyo, Samuel, Janha, R., Adiamoh, M, Adiamoh, Majidah, Njie F., Janha, Ramatoulie, Temple B., Temple, B., Diatta, Mathurin, Cheung Yin Bun, Ramatoulie Janha, Yin Bun Cheung, Nwakanma, D., Diatta M., David Conway, Temple, Beth, Snell, P, Walton R., Janha, R, Sisay Joof Fatou, Robert Walton, Sisay Joof, F, Samuel Dunyo, Conway, D., Sirugo, G, Sirugo, G., Dunyo, S., Nwakanma D., Temple, B, Sirugo, Giorgio, Janha Ramatoulie, Dunyo S., Njie, F., Dunyo, S, Nwakanma Davis, Paul Milligan, Walton Robert, Beth Temple, Conway, David, Mathurin Diatta, Paul Snell, Bisseye Cyrille, Sesay, S., Cheung, YB, Temple Beth, Janha R., Adiamoh, M., Milligan, Paul, Milligan, P., Cheung Y.B., Bisseye, C., Fatou Sisay Joof, Walton, Robert, Sesay Sanie, Diatta, M., Conway David, Sirugo G., Diatta, M, Majidah Adiamoh, Davis Nwakanma, Njie Fanta, Adiamoh M., Snell, Paul, Milligan, P, Sisay Joof, Fatou, Sirugo Giorgio, Dunyo Samuel, Conway, D, Fanta Njie, Adiamoh Majidah, Giorgio Sirugo, Cheung, Y. B.   +95 more
core   +1 more source