Results 21 to 30 of about 11,901 (167)

Concomitant nevirapine impacts pharmacokinetic exposure to the antimalarial artemether-lumefantrine in African children.

PLoS ONE, 2017
BackgroundThe antiretroviral drug nevirapine and the antimalarial artemisinin-based combination therapy artemether-lumefantrine are commonly co-administered to treat malaria in the context of HIV.
Liusheng Huang, Vincent Carey, Jane C Lindsey, Florence Marzan, David Gingrich, Bobbie Graham, Linda Barlow-Mosha, Phionah K Ssemambo, Portia Kamthunzi, Sharon Nachman, Sunil Parikh, Francesca T Aweeka, IMPAACT P1079 protocol team   +12 more
doaj   +1 more source

Pyronaridine–artesunate and artemether–lumefantrine for the treatment of uncomplicated Plasmodium falciparum malaria in Kenyan children: a randomized controlled non-inferiority trial

Malaria Journal, 2018
Background Pyronaridine–artesunate is a novel artemisinin-based combination therapy. The efficacy and safety of pyronaridine–artesunate were compared with artemether–lumefantrine for the treatment of uncomplicated Plasmodium falciparum malaria in ...
Johanna M. Roth, Patrick Sawa, Nicodemus Makio, George Omweri, Victor Osoti, Selpha Okach, Felix Choy, Henk D. F. H. Schallig, Pètra Mens   +8 more
doaj   +1 more source

Chlorproguanil−Dapsone−Artesunate versus Artemether−Lumefantrine : a randomized, double-blind phase III trial in African children and adolescents with uncomplicated plasmodium falciparum malaria [PDF]

, 2009
Chlorproguanil−dapsone−artesunate (CDA) was developed as an affordable, simple, fixed-dose artemisinin-based combination therapy for use in Africa. This trial was a randomized parallel-group, double-blind, double-dummy study to compare CDA and artemether−
Peter A Winstanley, Pamba Allan, Guiguemdé, Robert, Stephan Duparc, Paula L Kirby, Esamai, Fabian, Ezedinachi, Emmanuel U, Ward, S.A., Umeh, Rich E., Borrmann Steffen, Winstanley Peter A., Kirby, Paula L., Kellam, Lynda, Premji, Z., Greenwood, Brian, Ward, Stephen A, Premji, Zul, Lynda Kellam, Ezedinachi Emmanuel U., Oguche, Stephen, Owusu-Agyei, S., Stephen Oguche, Greenwood Brian, Oguche Stephen, Owusu-Agyei Seth, Winstanley, Peter A, Oguche, S, Emmanuel U Ezedinachi, Pamba, Allan, Rich E Umeh, Greenwood, B., Umeh Rich E., Zul Premji, Kellam, L., Winstanley, P.A., Duparc, Stephan, Owusu-Agyei, Seth, Duparc Stephan, Guiguemdé Robert, Guiguemde, R., Ward, S. A., Umeh, Rich Enujioke, Allan Pamba, Ward, Steve, Fabian Esamai, Ezedinachi, Emmanuel U., Umeh, R.E., Stephen A Ward, Kellam Lynda, Premji Zul, Esamai Fabian, Duparc, S., Kirby Paula L., Sowunmi Akintunde, Kirby, Paula L, Brian Greenwood, Pamba, A., Kirby, P.L., Rénia, Laurent, Ward Stephen A., Borrmann, S., Seth Owusu-Agyei, Robert Guiguemdé, Akintunde Sowunmi, Sowunmi, Akintunde, Ezedinachi, E.U., Umeh, Rich E, Sowunmi, A., Oguche, S., Borrmann, Steffen, Esamai, F., Steffen Borrmann, Winstanley, Peter, Winstanley, Peter A.   +73 more
core   +1 more source

Supervised versus unsupervised antimalarial treatment with six-dose artemether-lumefantrine: pharmacokinetic and dosage-related findings from a clinical trial in Uganda. [PDF]

, 2006
BACKGROUND: A six-dose antimalarial regimen of artemether-lumefantrine (A/L) may soon become one of the most widely used drug combination in Africa, despite possible constraints with adherence and poor absorption due to inadequate nutrition, and a lack ...
Bajunirwe, Francis, Piola, P, Piola, Patrice, Taylor, W R J, Babigumira, J, Kyomuhendo, J, Taylor, Walter R. J., Checchi, Francesco, Babigumira, Joseph, Ruzagira, E, Kyomuhendo, Juliet, Taylor, Walter RJ, Ferradini, Laurent, Kiguli, James, Kiguli, J, Ferradini, L, Fogg, C, Fogg, Carole, Bajunirwe, F, Guthmann, J P, Ruzagira, Eugene, Biraro, S, Kigozi, Isaac, Checchi, F, Guthmann, Jean-Paul, Biraro, Samuel, Grandesso, Francesco, Grandesso, F, Kigozi, I, Kyomuhendo Juliet, Laurent Ferradini, Francis Bajunirwe, Walter RJ Taylor, Carole Fogg, Eugene Ruzagira, Isaac Kigozi, Taylor Walter RJ, Ruzagira Eugene, Biraro Samuel, Piola Patrice, Fogg Carole, Francesco Checchi, Samuel Biraro, Babigumira Joseph, Kigozi Isaac, James Kiguli, Grandesso Francesco, Joseph Babigumira, Kiguli James, Jean-Paul Guthmann, Ferradini Laurent, Patrice Piola, Guthmann Jean-Paul, Francesco Grandesso, Checchi Francesco, Juliet Kyomuhendo, Bajunirwe Francis   +56 more
core   +1 more source

Artesunate + amodiaquine versus artemether-lumefantrine for the treatment of uncomplicated Plasmodium falciparum malaria in the Colombian Pacific region: a noninferiority trial

Revista da Sociedade Brasileira de Medicina Tropical, 2012
INTRODUCTION: In Colombia, there are no published studies for the treatment of uncomplicated Plasmodium falciparum malaria comparing artemisinin combination therapies.
Fernando De la Hoz Restrepo, Alexandra Porras Ramírez, Alejandro Rico Mendoza, Freddy Córdoba, Diana Patricia Rojas   +4 more
doaj   +1 more source

MOESM1 of Does artemetherâ lumefantrine administration affect mosquito olfactory behaviour and fitness?

, 2019
Additional file 1: Table S1. Pairwise comparison (LSD) of mosquito response to skin odour of eight participants in the olfactometer assay. Values in bold indicate significant differences.
de Boer, Jetske, Busula, Annette, ten Berge, Jet, van Dijk, Tessa, Takken, Willem   +4 more
openaire   +1 more source

Efficacy of Artemether-Lumefantrine in Treatment of Malaria Among Under-Fives and Prevalence of Drug Resistance Markers in Igombe-Mwanza, North-Western Tanzania. [PDF]

, 2012
\ud \ud Drug resistance to anti-malarials is a major public health problem worldwide. This study aimed at establishing the efficacy of artemether-lumefantrine (ACT) in Igombe-Mwanza, north-western Tanzania after a few years of ACT use, and establish the ...
Kamugisha, Erasmus, Minde Mercy, Kataraihya Johaness, Kironde, Fred, Kamugisha Erasmus, Erasmus Kamugisha, Jing, Sun, Kongola Gilbert, Mercy Minde, Kironde Fred, Jing Sun, Swedberg, Göte, Johaness Kataraihya, Kataraihya, Johaness, Swedberg Göte, Sun Jing, Gilbert Kongola, Kongola, Gilbert, Minde, Mercy, Fred Kironde, Göte Swedberg   +20 more
core   +1 more source

MOESM2 of Absence of in vivo selection for K13 mutations after artemetherâ lumefantrine treatment in Uganda

, 2017
Additional file 2. List of primers and probes for multiplex and qPCR for SNP typing in Plasmodium falciparum.
Balikagala, Betty, Mita, Toshihiro, Ikeda, Mie, Sakurai, Miki, Shouki Yatsushiro, Takahashi, Nobuyuki, Shin-Ichiro Tachibana, Auma, Mary, Ntege, Edward, Ito, Daisuke, Takashima, Eizo, Nirianne Palacpac, Egwang, Thomas, Onen, Joseph, Kataoka, Masatoshi, Eisaku Kimura, Horii, Toshihiro, Tsuboi, Takafumi   +17 more
openaire   +1 more source

Therapeutic failure after regimen with artemether-lumefantrine combination therapy: a report of three cases in Benin City, Nigeria

Revista da Sociedade Brasileira de Medicina Tropical, 2019
Artemisinin-based combination therapy (ACT) is recommended by the World Health Organization for the treatment of uncomplicated malaria. Currently, there appears to be a downward trend in the efficacy of ACT in some parts of sub-Saharan Africa because ...
Osamudiamen Ebohon, Francis Irabor, Linda Osahon Ebohon, Ehimwenma Sheena Omoregie   +3 more
doaj   +1 more source

MOESM1 of Absence of in vivo selection for K13 mutations after artemetherâ lumefantrine treatment in Uganda

, 2017
Additional file 1. Eligibility criteria for recruitment into the therapeutic efficacy study and the molecular study.
Balikagala, Betty, Mita, Toshihiro, Ikeda, Mie, Sakurai, Miki, Shouki Yatsushiro, Takahashi, Nobuyuki, Shin-Ichiro Tachibana, Auma, Mary, Ntege, Edward, Ito, Daisuke, Takashima, Eizo, Nirianne Palacpac, Egwang, Thomas, Onen, Joseph, Kataoka, Masatoshi, Eisaku Kimura, Horii, Toshihiro, Tsuboi, Takafumi   +17 more
openaire   +1 more source