Results 41 to 50 of about 12,135 (165)

Drug Interactions between Dolutegravir and Artemether-Lumefantrine or Artesunate-Amodiaquine [PDF]

, 2018
Across sub-Saharan Africa, patients with HIV on antiretrovirals often get malaria and need cotreatment with artemisinin-containing therapies. We undertook two pharmacokinetic studies in healthy volunteers, using standard adult doses of artemether ...
Mohammed Lamorde, Julian Kaboggoza, Alieu Amara, Winterberg, Markus, Stephen I Walimbwa, Catriona Waitt, Joshua Gini, Tarning, Joel, Justin Chiong, Pauline Byakika-Kibwika, Markus Winterberg, Saye H Khoo, Joel Tarning, Laura Else, Kaboggoza, Julian, Chiong, Justin, Khoo, Saye H, Walimbwa, Stephen I, Byakika-Kibwika, Pauline, Gini, Joshua, Waitt, Catriona, Lamorde, Mohammed, Amara, Alieu, Else, Laura   +23 more
core   +1 more source

Efficacy of artemether-lumefantrine and artesunate-amodiaquine as first line therapy of uncomplicated malaria in Burkina Faso, 11 years after policy change

The Pan African Medical Journal, 2020
INTRODUCTION: Artemether-lumefantrine (AL) and artesunate-amodiaquine (ASAQ) are the first line therapy of uncomplicated malaria in Burkina Faso. We assessed the treatment efficacy, tolerability of these drugs 11 years following its adoption as first ...
Issaka Zongo, Yves Daniel Compaoré, Frédéric Nikiéma, Moussa Zongo, Nouhoun Barry, Fabrice Anyirékun Somé, Naomie Kaboré, Jean Bosco Ouédraogo   +7 more
doaj   +1 more source

MOESM1 of Adherence to treatment with artemetherâ lumefantrine or amodiaquineâ artesunate for uncomplicated malaria in children in Sierra Leone: a randomized trial

, 2018
Additional file 1:Table S1.
Banek, Kristin, Webb, Emily, Smith, Samuel, Chandramohan, Daniel, Staedke, Sarah   +4 more
openaire   +1 more source

MOESM2 of A case of blackwater fever with persistent Plasmodium falciparum parasitaemia detected by PCR after artemetherâ lumefantrine treatment

, 2018
Additional file 2. Results of gametocyte-specific PCRsâ assays.
Huggan, Paul, Ng, Chin, Ho, Jennifer, Lin, Raymond, Chavatte, Jean-Marc   +4 more
openaire   +1 more source

Pyronaridine-artesunate granules versus artemether-lumefantrine crushed tablets in children with Plasmodium falciparum malaria: a randomized controlled trial

Malaria Journal, 2012
Background Children are most vulnerable to malaria. A pyronaridine-artesunate pediatric granule formulation is being developed for the treatment of uncomplicated Plasmodium falciparum malaria. Methods This phase III, multi-center, comparative, open-label,
Kayentao Kassoum, Doumbo Ogobara K, Pénali Louis K, Offianan André T, Bhatt Kirana M, Kimani Joshua, Tshefu Antoinette K, Kokolomami Jack HT, Ramharter Michael, de Salazar Pablo Martinez, Tiono Alfred B, Ouédraogo Alphonse, Bustos Maria Dorina G, Quicho Frederick, Borghini-Fuhrer Isabelle, Duparc Stephan, Shin Chang-Sik, Fleckenstein Lawrence   +17 more
doaj   +1 more source

MOESM2 of Efficacy of artemetherâ lumefantrine and dihydroartemisininâ piperaquine for the treatment of uncomplicated malaria in Papua New Guinea

, 2018
Additional file 2: Figure S1. Haemoglobin concentration.
Tavul, Livingstone, Hetzel, Manuel, Teliki, Albina, Dorish Walsh, Benson Kiniboro, Rare, Lawrence, Pulford, Justin, Siba, Peter, Karl, Stephan, Makita, Leo, Robinson, Leanne, Kattenberg, Johanna, Laman, Moses, Gilchrist Oswyn, Mueller, Ivo   +14 more
openaire   +1 more source

MOESM1 of Effectiveness and safety of 3 and 5Â day courses of artemetherâ lumefantrine for the treatment of uncomplicated falciparum malaria in an area of emerging artemisinin resistance in Myanmar

, 2018
Additional file 1. Contains trial profile, Additional figures, Additional results tables, and a summary of ultrasensitive PCR quality control procedures.
Tun, Kyaw, Jeeyapant, Atthanee, Myint, Aung, Kyaw, Zwe, Dhorda, Mehul, Mukaka, Mavuto, Cheah, Phaik, Imwong, Mallika, Hlaing, Thaung, Kyaw, Thar, Ashley, Elizabeth, Dondorp, Arjen, White, Nicholas, Day, Nicholas, Smithuis, Frank   +14 more
openaire   +1 more source

Genome‐Guided Discovery of Antimalarial 4‐Amino‐2,4‐Pentadienoate‐Containing Cyclolipodepsipeptides

Angewandte Chemie, Volume 138, Issue 18, 27 April 2026.
Halogenated and glycosylated 4‐amino‐2,4‐pentadienoate‐containing cyclolipodepsipeptides (APD‐CLDs) exhibit potent antiplasmodial activity (IC50 = 25–161 nM) against drug‐sensitive and resistant Plasmodium falciparum strains. ABSTRACT 4‐Amino‐2,4‐pentadienoate‐containing cyclolipodepsipeptides (APD‐CLDs) represent a structurally distinctive family of ...
Hartono Candra, Xue‐Jiao Wang, Ka Diam Go, Li Feng, Miaomiao Cai, Guang‐Lei Ma, Clarissa Widyantoro, Lik Tong Tan, Zbynek Bozdech, Zhe Wang, Zhao‐Xun Liang   +10 more
wiley   +2 more sources

MOESM3 of Efficacy and safety of artemetherâ lumefantrine as treatment for Plasmodium falciparum uncomplicated malaria in adult patients on efavirenz-based antiretroviral therapy in Zambia: an open label non-randomized interventional trial

, 2019
Additional file 3. Table on Cox regression analysis of risk of recrudescence by day 42 of follow-up.
Banda, Clifford, Chaponda, Mike, Mukaka, Mavuto, Mulenga, Modest, Hachizovu, Sebastian, Kabuya, Jean, Mulenga, Joyce, Sikalima, Jay, Kalilani-Phiri, Linda, Terlouw, Dianne, Khoo, Saye, Lalloo, David, Mwapasa, Victor   +12 more
openaire   +1 more source

Developmental Toxicity Study for the Antimalarial Drug Combination Cabamiquine‐Pyronaridine Using a Translational Approach

Birth Defects Research, Volume 118, Issue 10, October 2026.
ABSTRACT Background The safety of pharmacological treatments during pregnancy is a significant concern, as many medications lack comprehensive reproductive safety data. This creates gaps in therapeutic options for pregnant women, particularly malaria, which poses serious risks to maternal and fetal health.
Wookyung Kim, Geum‐Sil Cho, Andreas Gado, Tobias Hyun Ho Baeurle, Habib Karimi, Filippo Venezia, Claude Oeuvray, Thomas Spangenberg, Sebastian G. Wicha, Claudia Demarta‐Gatsi   +9 more
wiley   +1 more source