Results 31 to 40 of about 11,901 (167)

Measurement of adherence, drug concentrations and the effectiveness of artemether-lumefantrine, chlorproguanil-dapsone or sulphadoxine-pyrimethamine in the treatment of uncomplicated malaria in Malawi [PDF]

, 2009
Sulphadoxine-pyrimethamine (SP) is the only single dose therapy for uncomplicated malaria, but there is widespread resistance. At the time of this study, artemether-lumefantrine (AL) and chlorproguanil-dapsone (CPD), both multi-dose regimes, were ...
Hughes Dyfrig A, Mavuto Mukaka, Montgomery, Jacqui, Peter A Winstanley, Wootton, Dan, Winstanley Peter A, David G Lalloo, Molyneux Malcolm E, Bell, David J., Ward, Steve, Ward, Steve A., Chimpeni Phillips, Mukaka, Mavuto, Dyfrig A Hughes, Hughes, Dyfrig A., Steve A Ward, Wootton, Daniel G., Molyneux, Malcolm E., Lalloo David G, Phillips Chimpeni, Malcolm E Molyneux, Bell David J, Kayange Noel, Jacqui Montgomery, Ward Steve A, David J Bell, Noel Kayange, Mukaka Mavuto, Hughes, Dyfrig, Kayange, Noel, Lalloo, David G., Wootton Dan, Lalloo, David; id_orcid, Chimpeni, Phillips, Winstanley, Peter, Montgomery Jacqui, Dan Wootton, Winstanley, Peter A.   +37 more
core   +1 more source

Plasmodium falciparum and Schistosoma mansoni coinfection and the side benefit of artemether-lumefantrine in malaria patients

Journal of Infection in Developing Countries, 2013
Introduction: The distribution of both malaria and schistosomiasis exhibits a large geographical overlap in tropical environments, particularly in sub-Saharan Africa. This part of the world currently harbours more than 85% of the estimated global burden
Solomon M Abay, Mulugeta Tilahun, Nigus Fikrie, Abiy Habtewold   +3 more
doaj   +1 more source

MOESM4 of Absence of in vivo selection for K13 mutations after artemetherâ lumefantrine treatment in Uganda

, 2017
Additional file 4. Recrudescence versus re-infection test results of recurrent malaria infections.
Balikagala, Betty, Mita, Toshihiro, Ikeda, Mie, Sakurai, Miki, Shouki Yatsushiro, Takahashi, Nobuyuki, Shin-Ichiro Tachibana, Auma, Mary, Ntege, Edward, Ito, Daisuke, Takashima, Eizo, Nirianne Palacpac, Egwang, Thomas, Onen, Joseph, Kataoka, Masatoshi, Eisaku Kimura, Horii, Toshihiro, Tsuboi, Takafumi   +17 more
openaire   +1 more source

Effectiveness of Artemether-Lumefantrine Provided by Community Health Workers in Under-five Children with Uncomplicated Malaria in Rural Tanzania: An Open Label Prospective Study. [PDF]

, 2011
\ud Home-management of malaria (HMM) strategy improves early access of anti-malarial medicines to high-risk groups in remote areas of sub-Saharan Africa.
Petzold, M.G, Blessborn, D, Mårtensson, A, Malmberg, M, Carlsson, A.M, Gil, José P, Ngasala, Billy E, Malmberg Maja, Petzold, MG, Max G Petzold, Carlsson, Anja M, Ferreira, P.E, Premji, Z., Premji, Zul, Ferreira Pedro E, Pedro E Ferreira, Malmberg, Maja, Carlsson, Anja M., Gil, José Pedro, Bergqvist, Y, Bergqvist, Yngve, Ferreira, PE, Ngasala, B.E, Bergqvist, Y., Ferreira, Pedro E, Billy E Ngasala, Premji, Z, Gil, Jose P., Maja Malmberg, Zul Premji, Mårtensson, Andreas, Ngasala, Billy E., Yngve Bergqvist, Blessborn, Daniel,, Martensson, A., Petzold, Max G, Bergqvist, Yngve,, Mårtensson Andreas, Carlsson, AM, Ngasala Billy E, Gil, J.P., Petzold, M.G., Premji Zul, Ferreira, P.E., Ferreira, Pedro, José P Gil, Carlsson Anja M, Andreas Mårtensson, Ngasala, BE, Blessborn, D., Malmberg, M., Gil, J.P, Daniel Blessborn, Gil, JP, Blessborn Daniel, Petzold, Max G., Blessborn, Daniel, Anja M Carlsson, Gil José P, Ferreira, Pedro E., Carlsson, A.M., Petzold Max G, Bergqvist Yngve, Ngasala, B.E., Malmberg, M,   +64 more
core   +1 more source

Artemisinin combination therapies for treatment of uncomplicated malaria in Uganda. [PDF]

, 2006
OBJECTIVES: To compare the efficacy and safety of artemisinin combination therapies for the treatment of uncomplicated falciparum malaria in Uganda. DESIGN: Randomized single-blind controlled trial.
Staedke Sarah G, Rosenthal, Philip J, Yeka, Adoke, Banek, Kristin, Yeka Adoke, Dorsey, Grant, Staedke, Sarah G, Bakyaita Nathan, Dorsey Grant, Banek Kristin, Bukirwa, Hasifa, Talisuna Ambrose, Rosenthal Philip J, Talisuna, Ambrose, Rwakimari, John Bosco, Kamya Moses R, Kamya, Moses R, Bukirwa Hasifa, Wabwire-Mangen Fred, Bakyaita, Nathan, Wabwire-Mangen, Fred, Rwakimari John Bosco   +21 more
core   +1 more source

Formulation, process development and evaluation of artemether and lumefantrine soft gelatin capsule

Journal of Pharmacy and Bioallied Sciences, 2012
Artemether and Lumefantrine capsules are indicated for the treatment of P. falciparum malaria cases resistant to both chloroquine and sulphadoxine, pyrimethamine combination. Both artemether and lumefantrine act as blood schizontocides.
A Patel, A Lodha, J Chaudhuri, P Jadia, T Joshi, J Dalal   +5 more
doaj   +1 more source

Electrocardiographic safety evaluation of extended artemether-lumefantrine treatment in patients with uncomplicated Plasmodium falciparum malaria in Bagamoyo District, Tanzania

Malaria Journal, 2020
Background Extended artemisinin-based combination therapy (ACT) for treatment of uncomplicated Plasmodium falciparum malaria with already existing drug regimens, such as artemether-lumefantrine, might be effective in tackling the emerging ACT resistance.
Lwidiko E. Mhamilawa, Sven Wikström, Bruno P. Mmbando, Billy Ngasala, Andreas Mårtensson   +4 more
doaj   +1 more source

MOESM1 of A case of blackwater fever with persistent Plasmodium falciparum parasitaemia detected by PCR after artemetherâ lumefantrine treatment

, 2018
Additional file 1. Tests on molecular markers associated with anti-malarial drug resistance.
Huggan, Paul, Ng, Chin, Ho, Jennifer, Lin, Raymond, Chavatte, Jean-Marc   +4 more
openaire   +1 more source

Adherence to artemether/lumefantrine treatment in children under real-life situations in rural Tanzania. [PDF]

, 2012
A follow-up study was conducted to determine the magnitude of and factors related to adherence to artemether/lumefantrine (ALu) treatment in rural settings in Tanzania.
Zul Premji, Simba, Daudi O, Petzold, Max, Gustafsson, Lars L, Simba, D.O., Daudi O. Simba, Tomson, G., Mahindi, M., Goran Tomson, Lars L. Gustafsson, Kakoko, Deodatus, Max Petzold, Deodatus Kakoko, Margarita Mahindi, Kakoko, D., Petzold, M., Tomson, Goran, Gustafsson, L.L., Mahindi, Margarita, Premji, Zul   +19 more
core   +1 more source

Genome‐Guided Discovery of Antimalarial 4‐Amino‐2,4‐Pentadienoate‐Containing Cyclolipodepsipeptides

Angewandte Chemie, Volume 138, Issue 18, 27 April 2026.
Halogenated and glycosylated 4‐amino‐2,4‐pentadienoate‐containing cyclolipodepsipeptides (APD‐CLDs) exhibit potent antiplasmodial activity (IC50 = 25–161 nM) against drug‐sensitive and resistant Plasmodium falciparum strains. ABSTRACT 4‐Amino‐2,4‐pentadienoate‐containing cyclolipodepsipeptides (APD‐CLDs) represent a structurally distinctive family of ...
Hartono Candra, Xue‐Jiao Wang, Ka Diam Go, Li Feng, Miaomiao Cai, Guang‐Lei Ma, Clarissa Widyantoro, Lik Tong Tan, Zbynek Bozdech, Zhe Wang, Zhao‐Xun Liang   +10 more
wiley   +2 more sources