Results 81 to 90 of about 63,916 (252)

Factors Associated with Severe Disease from Malaria, Pneumonia and Diarrhea among Children in Rural Tanzania - a Hospital-Based Cross-Sectional Study. [PDF]

open access: yes, 2012
Mild cases of malaria, pneumonia and diarrhea are readily treatable with complete recovery and with inexpensive and widely available first-line drugs. However, treatment is complicated and expensive, and mortality is higher when children present to the ...
Hinderaker, Sven Gudmund   +2 more
core   +2 more sources

Red and Blue Light Promote the Accumulation of Artemisinin in Artemisia annua L.

open access: yesMolecules, 2018
Artemisinin, which has been isolated from Artemisia annua L., is the most effective antimalarial drug and has saved millions of lives. In addition, artemisinin and its derivatives have anti-tumor, anti-parasitic, anti-fibrosis, and anti-arrhythmic ...
Dong Zhang   +5 more
doaj   +1 more source

Paediatric malaria case-management with Artemether-Lumefantrine in Zambia: a repeat cross-sectional study [PDF]

open access: yes, 2007
BACKGROUND Zambia was the first African country to change national antimalarial treatment policy to artemisinin-based combination therapy – artemether-lumefantrine.
Dejan Zurovac   +36 more
core   +9 more sources

Low efficacy of the combination artesunate plus amodiaquine for uncomplicated falciparum malaria among children under 5 years in Kailahun, Sierra Leone. [PDF]

open access: yes, 2006
OBJECTIVE: In 2004, Sierra Leone adopted artesunate plus amodiaquine as first-line antimalarial treatment. We evaluated the efficacy of this combination in Kailahun, where a previous study had shown 70.2% efficacy of amodiaquine in monotherapy.
Balkan, S   +8 more
core   +2 more sources

Dihydroartemisinin Regulates the Th/Treg Balance by Inducing Activated CD4+ T cell Apoptosis via Heme Oxygenase-1 Induction in Mouse Models of Inflammatory Bowel Disease

open access: yesMolecules, 2019
Dihydroartemisinin (DHA) is a derivative of the herb Artemisia annua L. that has prominent immunomodulatory activity; however, its underlying mechanism remains elusive.
Si Chao Yan   +8 more
doaj   +1 more source

Mass campaigns with antimalarial drugs: a modelling comparison of artemether-lumefantrine and DHA-piperaquine with and without primaquine as tools for malaria control and elimination

open access: yes, 2015
Antimalarial drugs are a powerful tool for malaria control and elimination. Artemisinin-based combination therapies (ACTs) can reduce transmission when widely distributed in a campaign setting.
Eckhoff, Philip   +2 more
core   +1 more source

Declining Burden of Plasmodium vivax in a Population in Northwestern Thailand from 1995 to 2016 before Comprehensive Primaquine Prescription for Radical Cure. [PDF]

open access: yes, 2020
All Plasmodium cases have declined over the last decade in northwestern Thailand along the Myanmar border. During this time, Plasmodium vivax has replaced Plasmodium falciparum as the dominant species. The decline in P.
Carrara, Verena I   +6 more
core  

Clinical and parasitological response to oral chloroquine and primaquine in uncomplicated human Plasmodium knowlesi infections [PDF]

open access: yes, 2013
Background: Plasmodium knowlesi is a cause of symptomatic and potentially fatal infections in humans. There are no studies assessing the detailed parasitological response to treatment of knowlesi malaria infections in man and whether antimalarial ...
Cox Singh, Janet   +6 more
core   +1 more source

Artemisinin: current status

open access: yesTransactions of the Royal Society of Tropical Medicine and Hygiene, 1994
The compounds derived from the Chinese medicinal plant qinghao (Artemisia annua) are the most rapidly acting of all antimalarial drugs. They are effective when given parenterally, orally or by suppository. No serious adverse effect has yet been reported in humans.
openaire   +2 more sources

RWU Alumni Launch a New Way to Wage the Fight Against Malaria [PDF]

open access: yes, 2019
For two Roger Williams University alumni, seeing the first thriving crops of the sweet wormwood plant in the fields of Kentucky represent seeds of hope that their company’s new method of producing antimalarial medicine will revolutionize the fight ...
Rodrigues, Jill
core   +1 more source

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