Results 141 to 150 of about 5,742,584 (242)

Effects of Drug Resistance on the Global Spread of Malaria: A Systematic Literature Review

open access: yesHealth Science Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background and Aims Malaria remains a major health crisis in tropical regions, with Sub‐Saharan Africa bearing the heaviest burden. While insecticide‐treated nets and artemisinin‐based combination therapies (ACTs) have reduced cases, emerging parasite resistance to artemisinin threatens these gains. This review synthesizes evidence on how drug
Ashenafi Woldemichael Woime
wiley   +1 more source

Emerging threat of artemisinin partial resistance markers (pfk13 mutations) in Plasmodium falciparum parasite populations in multiple geographical locations in high transmission regions of Uganda

open access: yesMalaria Journal
Artemisinin-based combination therapy (ACT) is currently recommended for treatment of uncomplicated malaria. However, the emergence and spread of partial artemisinin resistance threatens their effectiveness for malaria treatment in sub-Saharan Africa ...
Bosco Agaba   +15 more
semanticscholar   +1 more source

Natural Product‐Derived Vesicles in Nanotherapeutics

open access: yesJournal of Extracellular Vesicles, Volume 15, Issue 9, September 2026.
Natural product‐derived vesicles (NPVs) are an emerging nature‐based nanotherapeutic that can deliver bioactive metabolites into the target site and induce beneficial mechanisms. A practical, chronological bench‐to‐bedside approach throughout the entire NPV development process is expected to resolve challenges encountered in NPV studies.
Kartiko Arif Purnomo, Tsong‐Long Hwang
wiley   +1 more source

The effects of pharmacogenetics on pharmacokinetics of artemisinin-based combinations in malaria patients [PDF]

open access: yes, 2009
Malaria is a vector-borne infectious disease caused by protozoan parasites of the genus Plasmodium. If not treated appropriately, human P. falciparum malaria can quickly become life-threatening, leading to an estimated 900’000 annual deaths globally. Key
Hodel, Eva Maria
core   +1 more source

Current status of artemisinin-resistant falciparum malaria in South Asia: a randomized controlled artesunate monotherapy trial in Bangladesh.

open access: yesPLoS ONE, 2012
ObjectiveRecent reports indicate that first cases of genuine artemisinin resistance have already emerged along the Thai-Cambodian border. The main objective of this trial was to track the potential emergence of artemisinin resistance in Bangladesh, which
Peter Starzengruber   +11 more
doaj   +1 more source

Artemisinin Partial Resistance in Ugandan Children With Complicated Malaria.

open access: yesJournal of the American Medical Association (JAMA)
This study assesses artemisinin partial resistance, Pfkelch13 variations, and malaria recrudescence in Ugandan children with complicated malaria.
R. Henrici   +11 more
semanticscholar   +1 more source

Amino Acid Metabolism in Health and Disease

open access: yesMedComm, Volume 7, Issue 9, September 2026.
This graphical abstract delineates the multifaceted role of amino acid metabolism in health and disease. It illustrates how amino acids sustain physiological homeostasis across the liver, kidney, brain, heart, intestine, muscle, skeleton, and immune system.
Zhiwei Su   +7 more
wiley   +1 more source

Artemisinin resistance in Myanmar [PDF]

open access: yesThe Lancet Infectious Diseases, 2015
Christopher V, Plowe, Pascal, Ringwald
openaire   +2 more sources

Traditional Chinese Medicine for lung cancer: Mechanisms, clinical evidence, and future perspectives

open access: yesPrecision Medical Sciences, Volume 15, Issue 3, Page 206-226, September 2026.
Graphical abstract represents the risk factors for lung cancer, TCM efficacy and clinical outcomes to future challenges. Abstract Lung cancer remains a leading cause of global cancer mortality. Despite advances in conventional treatments such as surgery, chemotherapy, targeted therapy, and immunotherapy, challenges including drug resistance, toxicity ...
Zhangdeng Chen, Liujun Bao
wiley   +1 more source

Simple field assays to check quality of current artemisinin-based antimalarial combination formulations. [PDF]

open access: yes, 2009
INTRODUCTION: Malaria continues to be one of the major public health problems in Africa, Asia and Latin America. Artemisinin derivatives (ARTs; artesunate, artemether, and dihydroartemisinin) derived from the herb, Artemisia annua, are the most effective
Ioset, Jean-Robert   +5 more
core   +2 more sources

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