Results 21 to 30 of about 15,257 (261)
More than anti-malarial agents: therapeutic potential of artemisinins in neurodegeneration
Neural Regeneration Research, 2019 Artemisinin, also called qinghaosu, is originally derived from the sweet wormwood plant (Artemisia annua), which is used in traditional Chinese medicine. Artemisinin and its derivatives (artemisinins) have been widely used for many years as anti-malarial
Bing-Wen Lu +4 more
doaj +1 more source
Frontiers in Oncology, 2022 Acute myeloid leukemia (AML) remains a devastating disease, with low cure rates despite intensive standard chemotherapy regimens. In the past decade, targeted antileukemic drugs have emerged from research efforts.
Amanda B. Kagan +7 more
doaj +1 more source
Recent advances in the treatment of Malaria
Biomedical Research Journal, 2016 Malaria is an infectious disease caused by protozoan parasites belonging to the Plasmodium species. The disease has been a major cause of mortality and morbidity, especially in populations of African and SouthEast Asian countries.
Sohal Satish +4 more
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Pharmaceutics, 2021 Because of the need to replace the current clinical artemisinins in artemisinin combination therapies, we are evaluating fitness of amino-artemisinins for this purpose.
Liezl Gibhard +8 more
doaj +1 more source
Frontiers in Plant Science, 2022 Artemisinin is a natural bioactive sesquiterpene lactone containing an unusual endoperoxide 1, 2, 4-trioxane ring. It is derived from the herbal medicinal plant Artemisia annua and is best known for its use in treatment of malaria.
Karim Farmanpour-Kalalagh +4 more
doaj +1 more source
Frontiers in Pharmacology, 2022 Artemisinin, isolated from the traditional Chinese medicinal plant qīng hāo 青蒿 (Artemisia annua) and its derivatives are used for treatment of malaria. With treatment failures now being recorded for the derivatives and companion drugs used in artemisinin
Jerome P. L. Ng +8 more
doaj +1 more source
Safety and efficacy of methylene blue combined with artesunate or amodiaquine for uncomplicated falciparum malaria [PDF]
, 2008 Besides existing artemisinin-based combination therapies, alternative safe, effective and affordable drug combinations against falciparum malaria are needed. Methylene blue (MB) was the first synthetic antimalarial drug ever used, and recent studies have
Coulibaly, Boubacar +10 more
core +1 more source
Frontiers in Pharmacology, 2020 Artemisinin and its derivatives have shown broad-spectrum antitumor activities in vitro and in vivo. Furthermore, outcomes from a limited number of clinical trials provide encouraging evidence for their excellent antitumor activities.
Cangcang Xu +3 more
doaj +1 more source
Exploration of in Vivo Efficacy of Artemether-Lumefantrine Against Uncomplicated Plasmodium Falciparum Malaria in Under Fives in Tabora Region, Tanzania. [PDF]
, 2013 Tanzania adopted artemether-lumefantrine (AL) as first-line drug for uncomplicated malaria in 2006. Recently, there was an anecdotal report on high malaria recurrence rate following AL treatment in in the (urban and peri-urban), western part of Tanzania.
Hulser, Ruth +5 more
core +3 more sources
Safety of Artemisinin Derivatives in the First Trimester of Pregnancy: A Controversial Story
Molecules, 2020 Artemisinin combination therapy (ACT) is recommended by the World Health Organization (WHO) as first line treatment for uncomplicated malaria both in adults and children.
Sarah D’Alessandro +4 more
doaj +1 more source