Results 51 to 60 of about 17,496 (173)

Potential applications of artemisinins in ocular diseases.

International Journal of Ophthalmology, 2019
Artemisinin, also named qinghaosu, is a family of sesquiterpene trioxane lactone originally derived from the sweet wormwood plant (Artemisia annua), which is a traditional Chinese herb that has been universally used as anti-malarial agents for many years.
B. Lu, Li-Ke Xie
semanticscholar   +1 more source

Anti-plasmodial polyvalent interactions in Artemisia annua L. aqueous extract – possible synergistic and resistance mechanisms [PDF]

Artemisia annua hot water infusion (tea) has been used in in vitro experiments against P. falciparum malaria parasites to test potency relative to equivalent pure artemisinin.
A Belkaid, A De Donno, A Nemeikaitė-Čėnienė, ABS Sidhu, Alexander P. Gorka, Alexei A. Lapkin, AR Bilia, AV Pandey, B Tepe, B Zhang, BC Elford, CW Jefford, CW Wright, D Cao, E Hsu, E Hsu, EG Yordi, F Van der Kooy, FH Jansen, G Noratto, Gabriele Pradel, Guy C. Barker, H Wagner, H Wagner, H Wagner, HJ Woerdenbag, İ Gülçin, J Golenser, J Mouton, J Suberu, J Wang, J-G Xu, John O. Suberu, K Liu, K Rath, L Cui, L Vivas, L-H Wang, Lauren Jacobs, M Friedman, M Petersen, M Willcox, M Willcox, MC Berenbaum, N Acton, N Erkan, N Klonis, Neil Sullivan, P Miketova, Paul D. Roepe, PG Bray, PJ Weathers, PJ Weina, PK Agrawal, PM De Magalhaes, PM O’Neill, PT Lansbury, QL Fivelman, R Feng, RK Haynes, RK Haynes, RT Eastman, S De Ridder, T Carbonara, TN Bennett, U Eckstein-Ludwig, W Li, XC Ding, Z Bozdech   +68 more
core   +1 more source

Electronic Nanomaterials for Plants: A Review on Current Advances and Future Prospects

Advanced Electronic Materials, EarlyView.
Global food security faces mounting challenges from climate change and rapid population growth. This review highlights the pivotal role of electronic nanomaterials–including metals, metal oxides, and carbon‐based structures–in enhancing plant photosynthesis, nutrient uptake, and stress resilience. Furthermore, it explores how emerging platforms such as
Ciro Allará, Giuseppe Ciccone, Manuela Ciocca, Sahira Vasquez, Pietro Ibba, Mauro Maver, Tanja Mimmo, Paolo Lugli, Luisa Petti   +8 more
wiley   +1 more source

Chemical stability of artemisinin derivatives [PDF]

Malaria Journal, 2012
Background Artemisinin derivatives are the most effective and fast acting antimalarials available. Several studies have demonstrated the presence of fake and bad quality antimalarials on the Asian and African market. Stability of artemisinin derivatives has so far only been partially investigated and it is unclear how much this contributes to the ...
Jacqueline Plaizier-Vercammen, Stijn Vanermen, Marc Mommaerts, Yvan Vander Heyden, Kristel Van Acker, Jolien Meskens   +5 more
openaire   +3 more sources

Harnessing the Biological Responses Induced by Nanomaterials for Enhanced Cancer Therapy

Aggregate, EarlyView.
Nanomaterial (NM)‐induced toxicity can be strategically repurposed for cancer therapy. This review summarizes the mechanism by which NMs selectively activate specific cellular processes to regulate cell fate independently. We also discussed how NMs‐induced biological responses can be leveraged as therapeutic strategies for cancer treatment.
Liting Wang, Hao Fu, Jiangtao Lin, Meng Zhao, Chuanrong Chen, Hongze Liao, Yourong Duan   +6 more
wiley   +1 more source

Research advancements and evaluation of multifactor‐induced murine models for gastric cancer

Animal Models and Experimental Medicine, EarlyView.
Murine models for gastric cancer. Abstract As one of the most prevalent gastrointestinal malignancies in humans, gastric cancer (GC) is often detected at an advanced stage, resulting in a poor prognosis and ranking it the fifth leading cause of cancer‐related deaths.
Yiqing Wang, Liang Zhang, Weixu Feng, Wanfeng Liu, Xiangyang Xue, Shiyu Feng   +5 more
wiley   +1 more source

Molecular markers of anti-malarial drug resistance in Central, West and East African children with severe malaria. [PDF]

, 2017
BACKGROUND: The Plasmodium falciparum multidrug resistance 1 (PfMDR1), P. falciparum Ca(2+)-ATPase (PfATP6) and Kelch-13 propeller domain (PfK13) loci are molecular markers of parasite susceptibility to anti-malarial drugs.
A Afonso, A Amambua-Ngwa, AB Sidhu, AB Sidhu, AC Uhlemann, AC Uhlemann, AC Uhlemann, AC Uhlemann, AF Cowman, AM Dondorp, AP Phyo, Ayola Akim Adegnika, B Greenwood, B Kwansa-Bentum, B Witkowski, Bernhards R. Ogutu, C Amaratunga, C Amaratunga, C Sisowath, Christian N. Nguetse, CN Nguetse, CN Nguetse, E Legrand, EA Ashley, EA Ashley, F Ariey, F Huang, F Koukouikila-Koussounda, F Nawaz, FL Eyase, G Holmgren, G Zhang, GS Humphreys, H Noedl, IH Cheeseman, IM Hastings, J Chilongola, J Straimer, JA Flegg, K Mugittu, K Na-Bangchang, K Tanabe, KJ Livak, M Malmberg, M Malmberg, M Miao, M Venkatesan, MB Reed, MD Spalding, MI Veiga, ML Ibrahim, MP Kyaw, MT Duraisingh, MT Duraisingh, MT Duraisingh, N Wurtz, NJ White, NO Duah, NW Lucchi, Peter G. Kremsner, PG Kremsner, PI Mayengue, R Jambou, R Jambou, R Tahar, RN Price, RN Price, S Cojean, S Krishna, S Krishna, S Meshnick, S Pulcini, S Ruetz, S Takala-Harrison, S Takala-Harrison, S Tukwasibwe, S Zakeri, Sanjeev Krishna, SG Valderramos, SK Mekonnen, Thirumalaisamy P. Velavan, TP Velavan, Tsiri Agbenyega, TT Thomsen, TT Thomsen, U Eckstein-Ludwig, WHO, WHO, WHO   +88 more
core   +1 more source

The Comprehensive Roadmap Toward Malaria Elimination Using Graphene and its Promising 2D Analogs

Advanced NanoBiomed Research, EarlyView.
Material based on a diversity of graphene with chemical properties of strong strength, high mobility, high transparency, good heat conductivity, biocompatibility, and chemical stability, advanced devices demonstrating antimalarial characteristics can be used for malaria treatment at different stages of malaria development from the injection of ...
Fangzhou He, George Junior, Rajashree Konar, Yuanding Huang, Ke Zhang, Lijing Ke, Meng Niu, Boon Tong Goh, Amine El Moutaouakil, Gilbert Daniel Nessim, Mohamed Belmoubarik, Weng Kung Peng   +11 more
wiley   +1 more source

Split dosing of artemisinins does not improve antimalarial therapeutic efficacy

Scientific Reports, 2017
It has been suggested recently, based on pharmacokinetic-pharmacodynamic modelling exercises, that twice daily dosing of artemisinins increases malaria parasite killing and so could “dramatically enhance and restore drug effectiveness” in artemisinin ...
N. J. White, N. J. White, James Watson, James Watson, E. Ashley   +4 more
semanticscholar   +1 more source

Production and characterization of different types of malaria pigment (hemozoin) and their potential use for screening for hemozoin inhibiting drugs [PDF]

, 2012
Tese de mestrado. Biologia (Microbiologia Aplicada). Universidade de Lisboa, Faculdade de Ciências, 2012Malarial pigment, hemozoin, appears to modulate the immune system, however it remains controversial if it has stimulatory or inhibitory effects ...
Góis, Ana Margarida Ferreira, 1988-
core