Growth inhibition and anticancer activity of phenoxyartemisinin derivatives in various cancer cell lines [PDF]
Journal of Medicine and Life ScienceCancer remains a significant global health challenge, underscoring the need for novel antineoplastic agents with improved efficacy and reduced toxicity.
Sangtae Oh +3 more
doaj +1 more source
Imported falciparum malaria among adults requiring intensive care: analysis of the literature. [PDF]
, 2014 BACKGROUND: Malaria is the most important imported tropical disease. Infection with Plasmodium falciparum is responsible for most of the morbidity and mortality.
Armstrong, Margaret +3 more
core +3 more sources
STING deficiency promotes motor recovery in mice following brachial plexus root avulsion
Animal Models and Experimental Medicine, EarlyView.STING deficiency can increase the body weight, promote motor recovery, decrease MN death, inhibit pyroptosis and neuroinflammation, increase remyelination, and reduce the atrophy of the biceps brachii in mice with BPRA. Abstract Background Brachial plexus root avulsion (BPRA), a well‐known form of peripheral nerve injury, results in motor function loss
Yu Peng +4 more
wiley +1 more source
Heme mediates cytotoxicity from artemisinin and serves as a general anti-proliferation target. [PDF]
PLoS ONE, 2009 Heme (Fe2+ protoporphyrin IX) is an essential molecule that has been implicated the potent antimalarial action of artemisinin and its derivatives, although the source and nature of the heme remain controversial.
Shiming Zhang, Glenn S Gerhard
doaj +1 more source
In Vitro and In Silico Antimalarial Evaluation of FM-AZ, a New Artemisinin Derivative
Medicines, 2022 Artemisinin-based Combination Therapies (ACTs) are currently the frontline treatment against Plasmodium falciparum malaria, but parasite resistance to artemisinin (ART) and its derivatives, core components of ACTs, is spreading in the Mekong countries ...
Ioannis Tsamesidis +7 more
doaj +1 more source
Delayed haemolysis after artesunate therapy in a cohort of patients with severe imported malaria due to Plasmodium falciparum [PDF]
, 2016 INTRODUCTION: Delayed haemolytic anaemia is one of the more frequent events after treatment with intravenous artesunate in patients with severe malaria.
Calvo-Cano, Antonia +4 more
core +1 more source
Biofuels, Bioproducts and Biorefining, EarlyView.Abstract The study identified process development priorities toward the feasible production of five value‐added biochemicals in a sugarcane biorefinery based on achievable bioconversion performances. Multiple process scenarios using A‐molasses as feedstock were simulated in Aspen Plus® via direct microbial conversions.
Manasseh K. Sikazwe +2 more
wiley +1 more source
Artemisinin–Second Career as Anticancer Drug?
World Journal of Traditional Chinese Medicine, 2015 Artemisinin represents a showcase example not only for the activity of medicinal herbs deriving from traditional chinese medicine, but for phytotherapy in general.
Thomas Efferth
doaj +1 more source
Do Health Workers' Preferences Influence their Practices? Assessment of Providers' Attitude and Personal use of new Treatment Recommendations for Management of Uncomplicated Malaria, Tanzania. [PDF]
, 2012 \ud \ud Due to growing antimalarial drug resistance, Tanzania changed malaria treatment policies twice within a decade. First in 2001 chloroquine (CQ) was replaced by sulfadoxine-pyrimethamine (SP) for management of uncomplicated malaria and by late 2006,
Khatib, Rashid A +2 more
core +3 more sources
BMEMat, EarlyView.This article introduces a biomimetic Mn‐doped polydopamine nanoplatform (HAMM NPs) coated with cancer cell membranes. It enables targeted hepatocellular carcinoma theranostics via T1/T2 dual‐mode magnetic resonance imaging and tumor microenvironment‐triggered sonodynamic therapy/chemodynamic therapy, achieving potent antitumor efficacy in subcutaneous ...
Jiayin Lin +7 more
wiley +1 more source