Engineering Cadherin‐Guided MSC Aggregates to Empower Synergistic Neurovascular Repair After Stroke
A cadherin‐directed bioengineering strategy transforms mesenchymal stem cell aggregation from passive clustering into active functional programming. The resulting cadherin‐guided aggregates exhibit reinforced microstructure, stress resistance, and an enhanced pro‐regenerative secretome, enabling coordinated neurovascular repair in ischemic stroke.
Guoqiang Chen +8 more
wiley +1 more source
Dynamic pseudo-continuous arterial spin labeling angiography using a 3D-radial multi-spoke spoiled gradient-recalled sequence. [PDF]
Petrovic A +6 more
europepmc +1 more source
Aerogel Scaffolds: Breathing Life Into Tissue Repair and Companion Diagnostics
Aerogel scaffolds are emerging as multifunctional biomedical platforms that bridge regenerative engineering and molecular diagnostics. By integrating hierarchical porosity, tunable mechanics, and programmable surface chemistry, aerogels can simultaneously support tissue reconstruction and enable localized biomarker sampling and signal transduction ...
Hanlin Zhang +5 more
wiley +1 more source
Prognostic Utility of Arterial Spin Labeling in Traumatic Brain Injury: From Pathophysiology to Precision Imaging. [PDF]
De Rosa S +3 more
europepmc +1 more source
Abstract The blood–brain barrier (BBB) maintains central nervous system homeostasis by regulating molecular exchange between blood and brain. BBB dysfunction is associated with aging and neurological disorders such as Alzheimer's disease, stroke, and multiple sclerosis.
Shakira A. van der Panne +14 more
wiley +1 more source
Assessing cerebral microvascular pulsatility using flow pulsatile-resolved pseudo-continuous arterial spin labeling MRI. [PDF]
Zhao T +5 more
europepmc +1 more source
[Color figure can be viewed at www.annalsofneurology.org] Among patients with acute ischemic stroke achieving successful large vessel recanalization (defined as expanded Thrombolysis in Cerebral Infarction [eTICI ≥2b]), incomplete tissue‐level reperfusion, distinct from visually identifiable distal occlusion on digital‐subtraction angiography, remains ...
Yue Qiao +4 more
wiley +1 more source
An applied study of blood oxygenation level-dependent and arterial spin labeling in early transplant renal function based on renal magnetic resonance angiography examination. [PDF]
Que C +8 more
europepmc +1 more source
Micro/Nanorobot for Drug Delivery—A Review of Material Selections
This review explores material strategies for biomedical micro/nanorobots, emphasizing their roles in propulsion, navigation, drug delivery, and biodegradability. It highlights advancements in metallic, polymeric, and hybrid materials, while addressing clinical translation challenges such as toxicity, immune response, and manufacturability.
Xiaozhuo Wu, Bingyun Li, Malcolm Xing
wiley +1 more source
MOdulation-Guided ENcoding (MOGEN) Scheme for Vessel-Encoded Arterial Spin Labeling
Li H +12 more
europepmc +1 more source

