Results 81 to 90 of about 3,674 (176)

PRRSV-2 nsp2 Ignites NLRP3 inflammasome through IKKβ-dependent dispersed trans-Golgi network translocation.

PLoS Pathogens
The NLRP3 inflammasome is a fundamental component of the innate immune system, yet its excessive activation is intricately associated with viral pathogenesis.
Lujie Zhang, Yanni Gao, Haoran Zhou, Xiao Liang, Xiaolin Jiang, Wenqin Gong, Yangyang Sun, Desheng Zhang, Xianwei Wang, Hans Nauwynck, Juan Bai, Ping Jiang   +11 more
doaj   +1 more source

Arterivírusok vizsgálata, különös tekintettel a hazai izolátumok genetikai tulajdonságaira = Investigation of arteriviruses with special regard to the genomic characteristics of local isolates [PDF]

, 2010
Az elmúlt négy évben vizsgáltuk a két állategészségügyi szempontból fontos arterivírus, a sertések szaporodásbiológiai zavarokkal és légzőszervi tünetekkel járó tünetegyüttesét előidéző vírus (PRRSV) és a lovak fertőző arteritisét előidéző vírus (EAV ...
Bakonyi, Tamás, Balka, Gyula, Hornyák, Ákos, Kecskeméti, Sándor, Kiss, István, Mándoki, Míra, Rusvai, Miklós, Tapaszti, Zsuzsanna   +7 more
core  

Proteome changes of lungs artificially infected with H-PRRSV and N-PRRSV by two-dimensional fluorescence difference gel electrophoresis [PDF]

, 2010
Background Porcine reproductive and respiratory syndrome with PRRS virus (PRRSV) infection, which causes significant economic losses annually, is one of the most economically important diseases affecting swine industry worldwide.
Shuqi Xiao, Qiwei Wang, Jianyu Jia, Peiqing Cong, Delin Mo, Xiangchun Yu, Limei Qin, Anning Li, Yuna Niu, Kongju Zhu, Xiaoying Wang, Xiaohong Liu, Yaosheng Chen   +12 more
core   +2 more sources

Refining Lineage Classification and Updated RFLP Patterns of PRRSV‐2 Revealed Viral Spatiotemporal Distribution Characteristics in China in 1991–2023

Transboundary and Emerging Diseases, Volume 2025, Issue 1, 2025.
Porcine reproductive and respiratory syndrome virus (PRRSV) is a significant infectious disease impacting the global swine industry. Due to high frequency of viral mutation and recombination, PRRSV exhibits complex genetic diversity; however, its lineage classification, restriction fragment length polymorphism (RFLP) patterns, and spatiotemporal ...
Xiaoxiao Tian, Ziyi Wei, Mirwaise Khan, Zhi Zhou, Jianqiang Zhang, Xinyi Huang, Yongbo Yang, Shujie Wang, Haiwei Wang, Xuehui Cai, Fandan Meng, Tongqing An, Nan-hua Chen   +12 more
wiley   +1 more source

Viruses Identified in Shrews (Soricidae) and Their Biomedical Significance

Viruses
Shrews (Soricidae) are common small wild mammals. Some species of shrews, such as Asian house shrews (Suncus murinus), have a significant overlap in their habitats with humans and domestic animals.
Huan-Yu Gong, Rui-Xu Chen, Su-Mei Tan, Xiu Wang, Ji-Ming Chen, Yuan-Long Zhang, Ming Liao   +6 more
doaj   +1 more source

Metagenomic sequencing generates the whole genomes of porcine rotavirus A, C, and H from the United States.

PLoS ONE, 2020
The genus Rotavirus comprises eight species, designated A to H, and two recently identified tentative species I in dogs and J in bats. Species Rotavirus A, B, C and H (RVA, RVB, RVC and RVH) have been detected in humans and animals.
Jennifer J A Hull, Mingpu Qi, Anna M Montmayeur, Deepak Kumar, Daniel E Velasquez, Sung-Sil Moon, Laura Cristal Magaña, Naga Betrapally, Terry Fei Fan Ng, Baoming Jiang, Douglas Marthaler   +10 more
doaj   +1 more source

Zoonotic potential of simian arteriviruses [PDF]

, 2015
Wild nonhuman primates are immediate sources and long-term reservoirs of human pathogens. However, ethical and technical challenges have hampered the identification of novel blood-borne pathogens in these animals.
Apetrei, Cristian, Bailey, Adam L, Freimer, Nelson B, Friedrich, Thomas C, Goldberg, Tony L, Jasinska, Anna J, Jolly, Clifford J, Kuhn, Jens H, Lauck, Michael, Marx, Preston A, O\u27Connor, David H, Phillips-Conroy, Jane E, Rogers, Jeffrey, Sibley, Samuel D   +13 more
core   +2 more sources

CRISPR/Cas system and its application in the diagnosis of animal infectious diseases

The FASEB Journal, Volume 38, Issue 24, 31 December 2024.
CRISPR‐based diagnostic platforms have transformed the molecular diagnostic field due to their outstanding ultra‐sensitive nucleic acid detecting capabilities. In this review, we highlighted the application of currently available CRISPR integrated setups on the diagnosis of animal infectious diseases.
Hafiz Muhammad Hamza Rasool, Qiwei Chen, Xiaowei Gong, Jizhang Zhou   +3 more
wiley   +1 more source

Porcine Reproductive and Respiratory Syndrome Virus, Thailand, 2010–2011

Emerging Infectious Diseases, 2012
Characterization of porcine reproductive and respiratory syndrome virus (PRRSV) isolates from pigs in Thailand showed 30-aa discontinuous deletions in nonstructural protein 2, identical to sequences for highly pathogenic PRRSV.
Dachrit Nilubol, Thitima Tripipat, Tawatchai Hoonsuwan, Khampee Kortheerakul   +3 more
doaj   +1 more source

Alternative codon usage of PRRS virus ORF5 gene increases eucaryotic expression of GP5 glycoprotein and improves immune response in challenged pigs [PDF]

, 2005
Pigs exposed to GP5 protein of PRRSV by means of DNA immunization develop specific neutralizing and protecting antibodies. Herein, we report on the consequences of codon bias, and on the favorable outcome of the systematic replacement of native codons ...
Cléroux, Patrick, Dea, Serge, Gagnon, Carl A., Jabrane, Ahmed, Kheyar, Ali, Massie, Bernard, Zhu, Chengru   +6 more
core   +1 more source