A porcine reproductive and respiratory syndrome virus (PRRSV) QY1 was serially passed on Marc‐145 cells. Virulence of different intermediate derivatives of QY1 (P5, P60, P80, and P100) were determined. The study found that QY1 had been gradually attenuated during the in vitro process.
Wenhui Lu +12 more
wiley +1 more source
Identification of a new cell line permissive to porcine reproductive and respiratory syndrome virus infection and replication which is phenotypically distinct from MARC-145 cell line [PDF]
Background Airborne transmitted pathogens, such as porcine reproductive and respiratory syndrome virus (PRRSV), need to interact with host cells of the respiratory tract in order to be able to enter and disseminate in the host organism.
Del Castillo, Jérôme +7 more
core +1 more source
Prevalence and Risk Factors of Toxoplasma gondii in Fattening Pigs Farm from Yucatan, Mexico
The objective of this study was to estimate the prevalence and identify risk factors associated with the presence of Toxoplasma gondii in pig‐fattening farms from Yucatan, Mexico. A cross‐sectional study was conducted with a two‐stage sampling. There were 429 pigs sampled from 39 farms randomly selected.
A. Ortega-Pacheco +6 more
wiley +1 more source
Impact of genotype 1 and 2 of porcine reproductive and respiratory syndrome viruses on interferon-α responses by plasmacytoid dendritic cells [PDF]
Porcine reproductive and respiratory syndrome (PRRS) virus (PRRSV) infections are characterized by prolonged viremia and viral shedding consistent with incomplete immunity.
Baumann, Arnaud +3 more
core +3 more sources
Endogenous Antimicrobial‐Immunomodulatory Molecules: Networking Biomolecules of Innate Immunity
A network of biomolecules (peptides, saccharides, lipids, nucleic acids, organic molecules, metal ions) endogenous to the human brain and exhibiting both antimicrobial and immunomodulatory activities has been identified. This network constitutes a previously uncatalogued and collectively underappreciated immuno‐active group of synergistic molecular ...
Donald F. Weaver
wiley +1 more source
The Development of Unconventional Extrathymic Activated CD4+CD8+ T Cells in Chagas Disease
The numbers of extrathymic CD4+CD8+ double‐positive (DP) T cells are augmented in various pathophysiological conditions, such as infectious diseases caused by intracellular pathogens, organs subjected to autoimmune attack and malignant tumors. The roles performed by extrathymic DP T cells are not clear, and it is not known how they are distributed in ...
Alexandre Morrot +3 more
wiley +1 more source
Applications of the Phytomedicine Echinacea purpurea (Purple Coneflower) in Infectious Diseases
Extracts of Echinacea purpurea (EP, purple coneflower) have been used traditionally in North America for the treatment of various types of infections and wounds, and they have become very popular herbal medicines globally. Recent studies have revealed that certain standardized preparations contain potent and selective antiviral and antimicrobial ...
James B. Hudson, Munekazu Iinuma
wiley +1 more source
Autophagy: New Questions from Recent Answers
Macroautophagy (hereafter autophagy) is currently one of the areas of medical life sciences attracting a great interest because of its pathological implications and therapy potentials. The discovery of the autophagy-related genes (ATGs) has been the key event in this research field because their study has led to the acquisition of new knowledge about ...
Fulvio Reggiori +3 more
wiley +1 more source
Generation of a candidate live marker vaccine for equine arteritis virus by deletion of the major virus neutralization domain [PDF]
Equine arteritis virus (EAV) is an enveloped plus-strand RNA virus of the family Arteriviridae (order Nidovirales) that causes respiratory and reproductive -disease in equids.
Castillo-Olivares, Javier +5 more
core +1 more source
Neonatal foal death due to infection with equine arteritis virus in Belgium [PDF]
This case report describes a small outbreak of neonatal foal death in Belgium due to infection with equine arteritis virus (EAV). The outbreak started with one foal suffering from acute dyspnea four days after birth.
Chiers, Koen +6 more
core

