Results 31 to 40 of about 26,165 (195)

The application of nano artesunate mixture in biomedicine

Tạp chí Khoa học Đại học Mở Thành phố Hồ Chí Minh - Kỹ thuật và Công nghệ, 2019
In this paper, nano β-cyclodextrin-alginate-artesunate nanoparticles ranging from 20nm to 80nm were synthesized, the fairly uniform diameters of particles were applied to enhance drug delivery.
Phạm Thị Hồng Tân
doaj   +1 more source

Addressing the challenge of neonatal mortality.

, 2013
Reducing neonatal mortality remains a challenge with an estimated 3.0 million neonatal deaths in 2011, three-quarters of these in sub-Saharan Africa and Southern Asia.
Blencowe, H, Cousens, S
core   +1 more source

Safety and efficacy of methylene blue combined with artesunate or amodiaquine for uncomplicated falciparum malaria [PDF]

, 2008
Besides existing artemisinin-based combination therapies, alternative safe, effective and affordable drug combinations against falciparum malaria are needed. Methylene blue (MB) was the first synthetic antimalarial drug ever used, and recent studies have
Coulibaly, Boubacar, Klose, Christina, Kouyaté, Bocar, Mansmann, Ulrich, Meissner, Peter E., Mockenhaupt, Frank P., Müller, Olaf, Schirmer, R. Heiner, Sié, Ali, Walter-Sack, Ingeborg, Zoungrana, Augustin   +10 more
core   +1 more source

Focusing on quality patient care in the new global subsidy for malaria medicines. [PDF]

, 2009
Tido von Schoen-Angerer and colleagues discuss the new Affordable Medicines Facility for malaria (AMFm), which subsidizes and facilitates access to artemisinin-based combination therapy, and what mechanisms are needed to ensure it stays focused on ...
Moon, S, Pérez Casas, C, Kindermans, J M, de Smet, M, von Schoen-Angerer, T   +4 more
core   +2 more sources

Genome‐Guided Discovery of Antimalarial 4‐Amino‐2,4‐Pentadienoate‐Containing Cyclolipodepsipeptides

Angewandte Chemie, Volume 138, Issue 18, 27 April 2026.
Halogenated and glycosylated 4‐amino‐2,4‐pentadienoate‐containing cyclolipodepsipeptides (APD‐CLDs) exhibit potent antiplasmodial activity (IC50 = 25–161 nM) against drug‐sensitive and resistant Plasmodium falciparum strains. ABSTRACT 4‐Amino‐2,4‐pentadienoate‐containing cyclolipodepsipeptides (APD‐CLDs) represent a structurally distinctive family of ...
Hartono Candra, Xue‐Jiao Wang, Ka Diam Go, Li Feng, Miaomiao Cai, Guang‐Lei Ma, Clarissa Widyantoro, Lik Tong Tan, Zbynek Bozdech, Zhe Wang, Zhao‐Xun Liang   +10 more
wiley   +2 more sources

Prevention of plant crown gall tumor development by the anti-malarial artesunate of Artemisia annua

Journal für Kulturpflanzen, 2009
The antimalarial drug artesunate, a sesquiterpene trioxane lactone derivative of artemisinin from Artemisia annua L., is known for its extraordinary inhibitory effects on plasmodia and trematodes and also for suppressing the proliferation of human tumor ...
Cornelia I. Ullrich, Monika von Eitzen-Ritter, Annemarie Jockel, Thomas Efferth   +3 more
doaj   +1 more source

Artesunate Inhibits the Development of Esophageal Cancer by Targeting HK1 to Reduce Glycolysis Levels in Areas With Zinc Deficiency

Frontiers in Oncology, 2022
Esophageal cancer (EC) threatens many lives in China, especially in areas with high incidences of EC. Our previous studies proved that zinc deficiency (ZD) promotes the cell cycle, thus promoting the progression of EC in areas with a high incidence of EC.
Jing Jin, Dongli Guo, Yingying Wang, Wenpeng Jiao, Daojuan Li, Yutong He   +5 more
doaj   +1 more source

Polymorphisms in Plasmodium falciparum chloroquine resistance transporter and multidrug resistance 1 genes: parasite risk factors that affect treatment outcomes for P. falciparum malaria after artemether-lumefantrine and artesunate-amodiaquine. [PDF]

, 2014
Adequate clinical and parasitologic cure by artemisinin combination therapies relies on the artemisinin component and the partner drug. Polymorphisms in the Plasmodium falciparum chloroquine resistance transporter (pfcrt) and P.
Adam, Ishag, Ademowo, George, Arze, Cesar, Asaq Molecular Marker Study Group, Baliraine, Frederick N, Berens-Riha, Nicole, Björkman, Anders, Borrmann, Steffen, Checchi, Francesco, Dahal, Prabin, Davis, Timothy ME, Desai, Meghna, Dhorda, Mehul, Djimdé, Abdoulaye A, Dorsey, Grant, El-Sayed, Badria B, Eshetu, Teferi, Eyase, Frederick, Falade, Catherine, Faucher, Jean-François, Fröberg, Gabrielle, Gadalla, Nahla B, Grivoyannis, Anastasia, Guérin, Philippe, Hamour, Sally, Houzé, Sandrine, Johnson, Jacob, Kamugisha, Erasmus, Kariuki, Simon, Kiechel, Jean-René, Kironde, Fred, Kofoed, Poul-Erik, LeBras, Jacques, Malmberg, Maja, Moriera, Clarissa, Mwai, Leah, Mårtensson, Andreas, Ménard, Didier, Ngasala, Billy, Nosten, Francois, Nsanzabana, Christian, Nsobya, Samuel L, Nzila, Alexis, Oguike, Mary, Ogutu, Bernhards, Otienoburu, Sabina Dahlström, Ouédraogo, Jean-Bosco, Piola, Patrice, Plowe, Christopher V, Price, Ric N, Rombo, Lars, Rosenthal, Philip J, Schramm, Birgit, Sibley, Carol Hopkins, Somé, A Fabrice, Stepniewska, Kasia, Sutherland, Colin J, Thwing, Julie, Ursing, Johan, Venkatesan, Meera, Wong, Rina PM, Zeynudin, Ahmed, Zongo, Issaka   +62 more
core   +4 more sources

Spectrophotometric analysis of artesunate injections available in community pharmacies in Northern and Western Uganda

Future Science OA
Aim The surge in different brands of artesunate injection in Uganda, has raised the need for this study, which aimed at quantifying the actual amount of artesunate in different brands of artesunate injections available in Northern and Western Uganda ...
Ebere Emilia Ayogu, Emmanuel Aryon Ngolryeko, Joseph Obiezu Chukwujekwu Ezeonwumelu, Ibrahim Garba Wawata, Bashir Olaniyi Sadiq   +4 more
doaj   +1 more source

Mode of action and choice of antimalarial drugs for intermittent preventive treatment in infants.

, 2009
Intermittent preventive treatment in infants (IPTi) is an effective and safe malaria control strategy. However, it remains unclear what antimalarials should be used to replace sulfadoxine-pyrimethamine (SP) when and where SP is no longer an effective ...
Cairns, Matthew, Gosling, Roly, Gesase, Samwel, Mosha, Jacklin, Greenwood, Brian, Chandramohan, Daniel   +5 more
core   +1 more source