Results 41 to 50 of about 18,290 (191)

The application of nano artesunate mixture in biomedicine

Tạp chí Khoa học Đại học Mở Thành phố Hồ Chí Minh - Kỹ thuật và Công nghệ, 2019
In this paper, nano β-cyclodextrin-alginate-artesunate nanoparticles ranging from 20nm to 80nm were synthesized, the fairly uniform diameters of particles were applied to enhance drug delivery.
Phạm Thị Hồng Tân
doaj   +1 more source

Trends in malaria morbidity following the introduction of artesunate plus amodiaquine combination in M'lomp village dispensary, south-western Senegal. [PDF]

, 2008
BACKGROUND: In Thailand, South Africa and Zanzibar, a decrease in malaria morbidity was observed following the introduction of artemisinin-based combination therapy (ACT).
Senghor Paul, Sophie Sarrassat, Le Hesran, Jean Yves, Paul Senghor, Hesran Jean, Le Hesran, Jean-Yves, Senghor, Paul, Jean Yves Le Hesran, Sophie SophieSarrassat, Sarrassat, Sophie, Sarrassat Sophie, Jean Hesran   +11 more
core   +1 more source

Prevention of plant crown gall tumor development by the anti-malarial artesunate of Artemisia annua

Journal für Kulturpflanzen, 2009
The antimalarial drug artesunate, a sesquiterpene trioxane lactone derivative of artemisinin from Artemisia annua L., is known for its extraordinary inhibitory effects on plasmodia and trematodes and also for suppressing the proliferation of human tumor ...
Cornelia I. Ullrich, Monika von Eitzen-Ritter, Annemarie Jockel, Thomas Efferth   +3 more
doaj   +1 more source

Artesunate Inhibits the Development of Esophageal Cancer by Targeting HK1 to Reduce Glycolysis Levels in Areas With Zinc Deficiency

Frontiers in Oncology, 2022
Esophageal cancer (EC) threatens many lives in China, especially in areas with high incidences of EC. Our previous studies proved that zinc deficiency (ZD) promotes the cell cycle, thus promoting the progression of EC in areas with a high incidence of EC.
Jing Jin, Dongli Guo, Yingying Wang, Wenpeng Jiao, Daojuan Li, Yutong He   +5 more
doaj   +1 more source

Spectrophotometric analysis of artesunate injections available in community pharmacies in Northern and Western Uganda

Future Science OA
Aim The surge in different brands of artesunate injection in Uganda, has raised the need for this study, which aimed at quantifying the actual amount of artesunate in different brands of artesunate injections available in Northern and Western Uganda ...
Ebere Emilia Ayogu, Emmanuel Aryon Ngolryeko, Joseph Obiezu Chukwujekwu Ezeonwumelu, Ibrahim Garba Wawata, Bashir Olaniyi Sadiq   +4 more
doaj   +1 more source

Protectiveness of Artesunate Given Prior Ischemic Cerebral Infarction Is Mediated by Increased Autophagy

Frontiers in Neurology, 2018
Background: Ischemic cerebral infarction is a severe clinical condition that can cause serious mortality. Artesunate, an anti-malarial drug that is widely used in cancer treatment, is known to facilitate accelerated cell apoptosis.
Ming Shao, Yue Shen, Hongjing Sun, Delong Meng, Wei Huo, Xu Qi   +5 more
doaj   +1 more source

Proteogenomic Profiling of Idiopathic Pulmonary Arterial Hypertension Identifies Sex‐Differential Proteins and Candidate Therapeutic Targets

Advanced Science, EarlyView.
An integrated proteogenomic analysis of 44,137 predominantly European‐ancestry UK Biobank participants aged 40–69 years identifies 12 robust proteins associated with idiopathic pulmonary arterial hypertension. These proteins define a high‐mortality molecular endotype, support early detection and mortality prediction, reveal sex‐differential proteomic ...
Xinjie Lin, Yangchang Zhang, Yang Pu, Duanke Liu, Tao Lei, Kai Ma, Qiyu He, Zheng Dou, Yuze Liu, Dengyuan Liu, Yinge He, Yanshang Wang, Xiaojiao Zheng, Yanbing Ma, Jianrong Zhou, Weiding Zhai, Binbin Su, Li Chen, Shoujun Li   +18 more
wiley   +1 more source

In-vivo efficacy of amodiaquine-artesunate in children with uncomplicated Plasmodium falciparum malaria in western Kenya.

, 2009
OBJECTIVES: To assess the efficacy of amodiaquine-artesunate in an area with high chloroquine resistance in western Kenya. METHODS: Twenty-eight day in-vivo efficacy trial of amodiaquine-artesunate in 103 children aged 6-59 months in western Kenya with ...
Thwing, JI, Slutsker, L, Odero, CO, McMorrow, M, Hamel, MJ, Desai, M, Odhiambo, FO, Otieno, KO, Kariuki, S, Roper, C, Vulule, J, Newman, RD, Ord, R   +12 more
core   +1 more source

Repeated treatment of recurrent uncomplicated Plasmodium falciparum malaria in Senegal with fixed-dose artesunate plus amodiaquine versus fixed-dose artemether plus lumefantrine: a randomized, open-label trial. [PDF]

, 2011
BACKGROUND: The use of artemisinin-based combination therapy (ACT) is currently recommended for treating uncomplicated malaria. The objective was to assess the efficacy and safety of repeated administrations of two fixed-dose presentations of ACT ...
Gaye Oumar, Ali Gueye, Corinne Tchania, Cissé, Badara, Tchania Corinne, Ibrahima Ndiaye, Barry Aichatou, Tine Roger, Gueye Ali, Tine, Roger, Ndiaye Daouda, Ndiaye, Ibrahima, Ndiaye, Daouda, Daouda Ndiaye, Valérie Lameyre, Gueye, Ali, Ndiaye Jean-Louis A, Roger Tine, Aichatou Barry, Tchania, Corinne, Faye, Babacar, Babacar Faye, Lameyre, Valérie, Cissé Badara, Ndiaye Ibrahima, Barry, Aichatou, Gaye, Oumar, Oumar Gaye, Faye Babacar, Ndiaye, Jean-Louis A, Jean-Louis A Ndiaye, Lameyre Valérie, Badara Cissé   +32 more
core   +1 more source

Aktivierung von Metallkomplexen durch Ultraschallwellen für eine gezielte Krebstherapie

Angewandte Chemie, EarlyView.
Ultrasound enables non‐invasive activation of metal‐based therapeutics deep within tumors. Acoustic cavitation can drive sonodynamic reactive oxygen species generation or mechanochemical metal–ligand bond dissociation, enabling controlled release of bioactive payloads.
Félix Grosjean, Nicolás Montesdeoca, Gilles Berger, Johannes Karges   +3 more
wiley   +1 more source