Results 41 to 50 of about 784,373 (290)

2019 American College of Rheumatology/Arthritis Foundation Guideline for the Treatment of Juvenile Idiopathic Arthritis: Therapeutic Approaches for Non‐Systemic Polyarthritis, Sacroiliitis, and Enthesitis

Arthritis care & research, 2019
To develop treatment recommendations for children with juvenile idiopathic arthritis manifesting as non‐systemic polyarthritis, sacroiliitis, or enthesitis.
S. Ringold, S. Angeles-Han, T. Beukelman, D. Lovell, Carlos A. Cuello, M. Becker, R. Colbert, B. Feldman, P. Ferguson, H. Gewanter, J. Guzman, J. Horonjeff, P. Nigrovic, Michael J. Ombrello, M. Passo, M. Stoll, C. Rabinovich, R. Schneider, O. Halyabar, K. Hays, A. A. Shah, Nancy M. Sullivan, A. Szymanski, Marat Turgunbaev, Amy S. Turner, J. Reston   +25 more
semanticscholar   +1 more source

Cumulative Incidence of Orofacial Manifestations in Early Juvenile Idiopathic Arthritis: A Regional, Three‐Year Cohort Study

Arthritis care & research, 2020
To estimate the cumulative incidence of arthritis‐induced orofacial symptoms, dysfunction, and dentofacial deformities in growing individuals with juvenile idiopathic arthritis (JIA) in a 36‐month regional cohort study and to identify predictors for the ...
P. Stoustrup, M. Glerup, A. E. Bilgrau, A. Küseler, C. Verna, A. E. Christensen, K. Kristensen, S. Nørholt, M. Twilt, T. Herlin, T. Pedersen   +10 more
semanticscholar   +1 more source

Association of the AFF3 gene and IL2/IL21 gene region with juvenile idiopathic arthritis [PDF]

, 2010
Recent genetic studies have led to identification of numerous loci that are associated with susceptibility to autoimmune diseases. The strategy of using information from these studies has facilitated the identification of novel juvenile idiopathic ...
Barton, A., British Society of Paediatric and Adolescent Rheumatology (BSPAR) Study Group, Childhood Arthritis Prospective Study (CAPS), Eyre, S., Flynn, E., Gardner-Medwin, J. [CAPS and BSPAR study groups], Hinks, A., Ke, X., Martin, P., Packham, J., Thomson, W., UKRAG Consortium, Worthington, J.   +12 more
core   +1 more source

Macrophage Activation Syndrome as Onset of Systemic Lupus Erythematosus: A Case Report and a Review of the Literature [PDF]

, 2015
Macrophage activation syndrome (MAS) is a potentially fatal condition. It is a rare complication of several autoimmune disorders, including systemic lupus erythematosus (SLE) and systemic juvenile idiopathic arthritis (sJIA).
Didona, Dario, Feola, Aldo, Granata, Guido, Granata, Massimo, Stifano, Giuseppina   +4 more
core   +4 more sources

Efficacy and Safety of Tocilizumab for Polyarticular‐Course Juvenile Idiopathic Arthritis in the Open‐Label Two‐Year Extension of a Phase III Trial

Arthritis & Rheumatology, 2020
To report the 2‐year efficacy and safety of tocilizumab (TCZ) in patients with polyarticular‐course juvenile idiopathic arthritis (JIA).
H. Brunner, N. Ruperto, Z. Żuber, R. Cuttica, V. Keltsev, R. Xavier, R. Burgos-Vargas, I. Calvo Penadés, E. Silverman, G. Espada, Manuel Ferrandiz Zavaler, Y. Kimura, C. Duarte, C. Job-Deslandre, R. Joos, W. Douglass, S. Wimalasundera, K. Bharucha, C. Wells, D. Lovell, A. Martini, F. De Benedetti   +21 more
semanticscholar   +1 more source

RISK FACTORS OF EARLY CARDIOVASCULAR PATHOLOGY OF CHILDREN SUFFERING FROM JUVENILE RHEUMATIC ARTHRITIS

Вопросы современной педиатрии, 2007
The article reviews the issue of risk factors of early cardiovascular pathology of children suffering from juvenile rheumatic arthritis. It presents research findings of lipid metabolism, endothelium dysfunction, hem stasis system pathology of rheumatic ...
E.Yu. Gudkova, E.I. Alexeeva
doaj   +2 more sources

Tapering Canakinumab Monotherapy in Patients With Systemic Juvenile Idiopathic Arthritis in Clinical Remission: Results From a Phase IIIb/IV Open‐Label, Randomized Study

Arthritis & Rheumatology, 2020
To evaluate the efficacy and safety of 2 canakinumab monotherapy tapering regimens in order to maintain complete clinical remission in children with systemic juvenile idiopathic arthritis (JIA).
P. Quartier, E. Alexeeva, C. Tamás, V. Chasnyk, N. Wulffraat, K. Palmblad, C. Wouters, H. Brunner, K. Marzan, R. Schneider, G. Horneff, A. Martini, J. Antón, Xiaoling Wei, A. Slade, N. Ruperto, K. Abrams   +16 more
semanticscholar   +1 more source

Relationships among gut microbiota, plasma metabolites, and juvenile idiopathic arthritis: a mediation Mendelian randomization study

Frontiers in Microbiology
ObjectiveThe objective of this study is to investigate the causal relationship between gut microbiota and juvenile idiopathic arthritis, and to identify and quantify the potential role of plasma metabolites as mediators.MethodsUsing summary-level data ...
Bingjun Gao, Zhe Wang, Kunyao Wang, Yinghan Lei, Yan Zhuang, Zhonghua Zhou, Junfei Chen   +6 more
doaj   +1 more source

Guilt by association - what is the true risk of malignancy in children treated with etanercept for JIA?

Pediatric Rheumatology Online Journal, 2010
Recently, the Food and Drug Administration placed a "black box" label on etanercept, and other tumor necrosis factor inhibitors used to treat childhood arthritis, warning of the risk of malignancies.
Cron Randy Q, Beukelman Timothy
doaj   +1 more source

Different corticosteroid induction regimens in children and young people with juvenile idiopathic arthritis: the SIRJIA mixed-methods feasibility study

Health Technology Assessment, 2020
Background: In the UK, juvenile idiopathic arthritis is the most common inflammatory disorder in childhood, affecting 10 : 100,000 children and young people aged
Ashley P Jones, Dannii Clayton, Gloria Nkhoma, Frances C Sherratt, Matthew Peak, Simon R Stones, Louise Roper, Bridget Young, Flora McErlane, Tracy Moitt, Athimalaipet V Ramanan, Helen E Foster, Paula R Williamson, Samundeeswari Deepak, Michael W Beresford, Eileen M Baildam   +15 more
doaj   +1 more source