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Rheumatoid arthritis

The Lancet, 2010
Rheumatoid arthritis is characterised by persistent synovitis, systemic inflammation, and autoantibodies (particularly to rheumatoid factor and citrullinated peptide). 50% of the risk for development of rheumatoid arthritis is attributable to genetic factors. Smoking is the main environmental risk.
Scott, D.L., Wolfe, F., Huizinga, T.W.J.
openaire   +6 more sources

Rheumatoide Arthritis

Therapeutische Umschau, 2023
Zusammenfassung. Die Rheumatoide Arthritis (RA) ist die häufigste entzündliche Gelenkerkrankung mit einer Prävalenz von 1% weltweit. Die Krankheitsentstehung ist durch ein komplexes Zusammenspiel von genetischen, epigenetischen und Umwelt-Faktoren bestimmt, das noch ungenügend bekannt ist.
Julia, Lehmann, Diego, Kyburz
openaire   +2 more sources

Epidemiology of Rheumatoid Arthritis: Rheumatoid Arthritis and Mortality

Current Rheumatology Reports, 2010
Increased mortality in rheumatoid arthritis (RA) is widely recognized but not fully explained. Despite substantial improvements in management and growing knowledge of the determinants of increased mortality, evidence for reduction in mortality in RA has lagged behind. Indeed, most studies report no apparent reduction in mortality in RA.
Sherine E. Gabriel   +3 more
openaire   +3 more sources

Rheumatoide Arthritis

Zeitschrift für Rheumatologie, 2018
Rheumatoid arthritis (RA) is a chronic and progressive systemic disease of the connective tissue, which is particularly manifested with destructive alterations to the joints. Inflammatory reactions in the synovium lead to the influx of peripheral inflammatory cells as well as the activation of local cells.
E, Neumann   +3 more
openaire   +2 more sources

Juvenile rheumatoid arthritis

Postgraduate Medicine, 1977
Juvenile rheumatoid arthritis is the condition of chronic synovitis in children. This Condition was first well described in the English literature by George Frederick Still,1 an English pediatrician and pathologist, who in 1897 described 22 children with chronic arthritis who had come to his attention while he was still in training at the Hospital for ...
openaire   +7 more sources

Preclinical Rheumatoid Arthritis and Rheumatoid Arthritis Prevention

Current Rheumatology Reports, 2018
This review is to provide an update on the current understanding of rheumatoid arthritis (RA) development related to disease development prior to the onset clinically apparent synovitis and opportunities for disease prevention.A growing number of studies have demonstrated that serum elevations of autoantibodies rheumatoid factor and antibodies to ...
openaire   +3 more sources

Rheumatoid arthritis

The Lancet, 2001
Rheumatoid arthritis is a systemic inflammatory disorder that mainly affects the diarthrodial joint. It is the most common form of inflammatory arthritis, and has a substantial societal effect in terms of cost, disability, and lost productivity. Although the pathogenesis of rheumatoid arthritis remains incompletely understood, much insight into the ...
D M, Lee, M E, Weinblatt
openaire   +2 more sources

Rheumatoid Arthritis

Foot and Ankle Clinics, 2007
This article reviews rheumatoid arthritis, a chronic disease that primarily targets the joints, its treatment and antirheumatic drugs.
openaire   +2 more sources

Rheumatoid Arthritis

2012
Rheumatoid arthritis (RA) is an idiopathic systemic autoimmune disorder that primarily involves the joints. It causes inflammation of the synovium (synovitis) that can lead to cartilage destruction and bone erosions. Extra-articular manifestations may also occur.
Derrick J. Todd, Jonathan S. Coblyn
openaire   +1 more source

Molecular and Cellular Heterogeneity in Rheumatoid Arthritis: Mechanisms and Clinical Implications

Frontiers in Immunology, 2021
Ling Qin, Shicheng Guo, Steven J Schrodi
exaly  

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