Results 151 to 160 of about 832,855 (337)

Evolutionary Codesign and Fabrication of Tensegrity Joints with Integrated Pneumatic Artificial Muscles

open access: yesAdvanced Intelligent Systems, EarlyView.
This study presents a tensegrity joint with pneumatic artificial muscles integrated directly into its tensile network. Inspired by tensegrity spine structures, the joint's topology is developed and further optimized through an evolutionary algorithm, taking into account fabrication constraints and target applications.
Jan Petrš   +5 more
wiley   +1 more source

Promoting radical healing to facilitate community capacity building among formerly incarcerated Black and Latino men with substance use disorders

open access: yesAmerican Journal of Community Psychology, EarlyView.
Abstract This study reports on a qualitative thematic analysis of secondary data from group session recordings collected as part of the Community Wise Optimization Trial. Community Wise is a multilevel behavioral intervention designed to increase critical consciousness and reduce substance use among formerly incarcerated men living in predominantly ...
Richmond E. Hayes   +4 more
wiley   +1 more source

How effective is proximal fibular osteotomy in redistributing joint pressures? Insights from an HTO comparative in-silico study

open access: yesJournal of Orthopaedic Surgery and Research
Background Knee osteoarthritis (KOA) represents a widespread degenerative condition among adults that significantly affects quality of life. This study aims to elucidate the biomechanical implications of proximal fibular osteotomy (PFO), a proposed cost ...
Jorge Eduardo Morales Avalos   +7 more
doaj   +1 more source

Intra-articular injection of inorganic pyrophosphate improves IL-1β-induced cartilage damage in rat model of knee osteoarthritis in vivo

open access: yesOsteoarthritis and Cartilage Open
Objective: Osteoarthritis (OA) is the most common form of chronic joint disease, affecting mainly the elderly population. This disorder is caused by cartilage degeneration with complex changes in the chondrocyte phenotype.
Émilie Velot   +3 more
doaj  

Two New Cases Expand the Phenotypic Spectrum of TUBG1 Missense Variants

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT The gamma‐tubulin ring complex (γ‐TuRC) plays a role in coordinating centrosome and spindle pole body formation during cell division. TUBG1 encodes a critical component of the γ‐TuRC. Pathogenic TUBG1 variants can cause a range of alterations in cortical gyral patterning, microcephaly, and other neurological manifestations.
Roser Urreizti   +12 more
wiley   +1 more source

Worth the Effort: Lessons for Discovery and Care From an Unusual Case of Gorlin Syndrome

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Gorlin‐Goltz Syndrome (GGS) is a rare autosomal dominant genetic disorder encompassing a diverse range of clinical manifestations, including congenital anomalies and predisposition to cancer. Pathogenic variants in PTCH1 and SUFU account for up to 79% and 6% of cases, respectively. Currently, an estimated 15%–27% of individuals with a clinical
V. Taliercio   +13 more
wiley   +1 more source

Prognostic significance of NUAK1 and its association with immune infiltration in stomach adenocarcinoma

open access: yesDiscover Oncology
Background Stomach adenocarcinoma (STAD) represents a significant global health burden, accounting for a considerable proportion of cancer-related mortalities, and NUAK1, a protein kinase, plays a crucial role in cellular metabolism, cell cycle ...
Xin Ni, Fan Pan, Ya Kun Lang, Wei Zhang
doaj   +1 more source

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