Research progress of self-assembling peptide hydrogels in repairing cartilage defects
Due to the lack of blood vessels, nerves and lymphatic vessels, the capacity of articular cartilage to heal is extremely limited. Once damaged, it is urgent for articular cartilage to repair the injury.
Renyi Wang +8 more
doaj +1 more source
Ionic Control of Microstructure and Lubrication in Charged, Physically Cross‐Linked Hydrogels
Here, charged, physically cross‐linked poly(methacrylamide‐co‐methacrylic acid) hydrogels stabilized by a short‐range attractive, long‐range repulsive potential is investigated. This work uncovers how salt addition alters not only swelling, but also the microstructure and dynamics, near‐surface stiffness and charge, and ultimately, its lubricity. Salts
Alexander Deptula +1 more
wiley +1 more source
Effects of radiopharmaceuticals on articular cartilage’s mechanical properties
As radiation science and technology advances, nuclear medicine applications are increasing worldwide which necessitate the understanding of biological implications of such practices.
Kuzu Nihal, Cicek Ekrem
doaj +1 more source
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz +3 more
wiley +1 more source
Chondrogenic potential of human articular chondrocytes and skeletal stem cells: a comparative study
Regenerative medicine strategies have increasingly focused on skeletal stem cells (SSCs), in response to concerns such as donor site morbidity, dedifferentiation and limited lifespan associated with the use of articular chondrocytes for cartilage repair.
Li, Siwei +3 more
core +1 more source
Transient anabolic effects accompany epidermal growth factor receptor signal activation in articular cartilage in vivo [PDF]
INTRODUCTION: Signals from the epidermal growth factor receptor (EGFR) have typically been considered to provide catabolic activities in articular cartilage, and accordingly have been suggested to have a causal role in osteoarthritis progression. The aim
Caroline N Dealy +4 more
core +1 more source
Intra-articular drug delivery systems for osteoarthritis therapy: shifting from sustained release to enhancing penetration into cartilage [PDF]
Huirong Huang +7 more
openalex +1 more source
LipoGels: Robust Self‐Lubricating Physically Cross‐Linked Alginate Hydrogels Embedded with Liposomes
Physically cross‐linked alginate hydrogels embedded with 1,2‐dipalmitoyl‐sn‐glycero‐3‐phosphocholine liposomes (LipoGels) are prepared under optimized conditions to avoid shrinkage and achieve structural uniformity. LipoGels demonstrate robust mechanical strength (Young's modulus ≈1 MPa), excellent lubrication (friction coefficient ≈0.021), and ...
Tao Ma +4 more
wiley +1 more source
Cartilaginous Organoids: Advances, Applications, and Perspectives
Cartilage is a nonvascular and non‐neural, mesoderm‐derived tissue. Cartilage repair, especially articular cartilage repair and reconstruction, has always been a difficult problem in bone tissue engineering.
Yuhao Yu +4 more
doaj +1 more source
Osteoarthritis (OA) is the most common age-related degenerative joint disease mainly characterized by the destruction of articular cartilage. Owing to its native avascular property, intrinsic repair of articular cartilage is very limited.
Kai Feng +7 more
doaj +1 more source

