Results 71 to 80 of about 457,350 (333)

Characterization of costal cartilage and its suitability as a cell source for articular cartilage tissue engineering

open access: yesJournal of Tissue Engineering and Regenerative Medicine, 2018
Costal cartilage is a promising donor source of chondrocytes to alleviate cell scarcity in articular cartilage tissue engineering. Limited knowledge exists, however, on costal cartilage characteristics. This study describes the characterization of costal
Le W Huwe   +3 more
semanticscholar   +1 more source

3D (Bio) Printing Combined Fiber Fabrication Methods for Tissue Engineering Applications: Possibilities and Limitations

open access: yesAdvanced Functional Materials, EarlyView.
Biofabrication aims at providing innovative technologies and tools for the fabrication of tissue‐like constructs for tissue engineering and regenerative medicine applications. By integrating multiple biofabrication technologies, such as 3D (bio) printing with fiber fabrication methods, it would be more realistic to reconstruct native tissue's ...
Waseem Kitana   +2 more
wiley   +1 more source

A Measure of Control for Secondary Cytokine-Induced Injury of Articular Cartilage: A Computational Study [PDF]

open access: yes, 2013
In previous works, the author and collaborators establish a mathematical model for injury response in articular cartilage. In this paper we use mathematical software and computational techniques, applied to an existing model to explore in more detail how
Graham, Jason M
core  

Transient anabolic effects accompany epidermal growth factor receptor signal activation in articular cartilage in vivo [PDF]

open access: yes, 2013
INTRODUCTION: Signals from the epidermal growth factor receptor (EGFR) have typically been considered to provide catabolic activities in articular cartilage, and accordingly have been suggested to have a causal role in osteoarthritis progression. The aim
Caroline N Dealy   +4 more
core   +1 more source

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

open access: yesAdvanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth   +2 more
wiley   +1 more source

Cartilaginous Organoids: Advances, Applications, and Perspectives

open access: yesAdvanced NanoBiomed Research, 2023
Cartilage is a nonvascular and non‐neural, mesoderm‐derived tissue. Cartilage repair, especially articular cartilage repair and reconstruction, has always been a difficult problem in bone tissue engineering.
Yuhao Yu   +4 more
doaj   +1 more source

Injectable hypoxia-preconditioned cartilage progenitor cells-laden GelMA microspheres system for enhanced osteoarthritis treatment

open access: yesMaterials Today Bio, 2023
Osteoarthritis (OA) is the most common age-related degenerative joint disease mainly characterized by the destruction of articular cartilage. Owing to its native avascular property, intrinsic repair of articular cartilage is very limited.
Kai Feng   +7 more
doaj   +1 more source

Chondrocyte outgrowth into a gelatin scaffold in a single impact load model of damage/repair - effect of BMP-2. [PDF]

open access: yes, 2011
BACKGROUND: Articular cartilage has little capacity for repair in vivo, however, a small number of studies have shown that, in vitro, a damage/repair response can be induced.
Henson, Frances MD, Vincent, Thea
core   +1 more source

Ionic Control of Microstructure and Lubrication in Charged, Physically Cross‐Linked Hydrogels

open access: yesAdvanced Functional Materials, EarlyView.
Here, charged, physically cross‐linked poly(methacrylamide‐co‐methacrylic acid) hydrogels stabilized by a short‐range attractive, long‐range repulsive potential is investigated. This work uncovers how salt addition alters not only swelling, but also the microstructure and dynamics, near‐surface stiffness and charge, and ultimately, its lubricity. Salts
Alexander Deptula   +1 more
wiley   +1 more source

Magnetically targeted delivery through cartilage

open access: yesAIP Advances, 2018
In this study, we have invented a method of delivering drugs deep into articular cartilage with shaped dynamic magnetic fields acting on small metallic magnetic nanoparticles with polyethylene glycol coating and average diameter of 30 nm.
Sahar Jafari   +11 more
doaj   +1 more source

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