Results 11 to 20 of about 43,162 (263)

Resurfacing damaged articular cartilage to restore compressive properties [PDF]

Journal of Biomechanics, 2015
Surface damage to articular cartilage is recognized as the initial underlying process causing the loss of mechanical function in early-stage osteoarthritis. In this study, we developed structure-modifying treatments to potentially prevent, stabilize or reverse the loss in mechanical function.
Stephanie, Grenier, Patrick E, Donnelly, Jamila, Gittens, Peter A, Torzilli   +3 more
openaire   +2 more sources

An acquired plica-induced notch in the medial femoral condyle in a patient with medial patellar plica syndrome: a case report

BMC Musculoskeletal Disorders, 2021
Background An inflamed and thickened medial patellar plica (MPP) caused by repeated mechanical irritation from trauma or overuse leads to impingement between the anterior medial femoral condyle and the medial articular facet of the patella and produces ...
Sung-Jae Kim, Yong Gon Koh, Yong Sang Kim   +2 more
doaj   +1 more source

Causes of mechanically induced collagen damage in articular cartilage [PDF]

Journal of Orthopaedic Research, 2005
AbstractOsteoarthritis (OA) is a multifactorial disease, associated with articular cartilage degeneration and eventually joint destruction. The phases of the disease have been described in detail, and mechanical factors play an important role in the initiation of OA, but many questions remain about its etiology.
Wilson, W., Burken, C. van, Donkelaar, C.C. van, Buma, P., Rietbergen, B. van, Huiskes, R.   +5 more
openaire   +3 more sources

Hydrogels as a Replacement Material for Damaged Articular Hyaline Cartilage [PDF]

Materials, 2016
Hyaline cartilage is a strong durable material that lubricates joint movement. Due to its avascular structure, cartilage has a poor self-healing ability, thus, a challenge in joint recovery. When severely damaged, cartilage may need to be replaced. However, currently we are unable to replicate the hyaline cartilage, and as such, alternative materials ...
Charlotte Beddoes, Michael Whitehouse, Wuge Briscoe, Bo Su   +3 more
openaire   +4 more sources

Oxidative DNA damage in osteoarthritic porcine articular cartilage [PDF]

Journal of Cellular Physiology, 2008
AbstractOsteoarthritis (OA) is associated with increased levels of reactive oxygen species. This study investigated if increased oxidative DNA damage accumulates in OA articular cartilage compared with non‐OA articular cartilage from pigs with spontaneous OA.
Antonia F, Chen, Catrin M, Davies, Ming, De Lin, Beverley, Fermor   +3 more
openaire   +2 more sources

Mesenchymal Stem Cells for Treating Articular Cartilage Defects and Osteoarthritis

Cell Transplantation, 2015
Articular cartilage damage and osteoarthritis are the most common joint diseases. Joints are prone to damage caused by sports injuries or aging, and such damage regularly progresses to more serious joint disorders, including osteoarthritis, which is a ...
Yu Wang, Mei Yuan, Quan-Yi Guo, Shi-Bi Lu, Jiang Peng   +4 more
doaj   +1 more source

Use of mesenchymal stem cells seeded on the scaffold in articular cartilage repair

Inflammation and Regeneration, 2018
Articular cartilage has poor capacity for repair. Once damaged, they degenerate, causing functional impairment of joints. Allogeneic cartilage transplantation has been performed for functional recovery of articular cartilage.
Kaoru Yamagata, Shingo Nakayamada, Yoshiya Tanaka   +2 more
doaj   +1 more source

A partial hemi-resurfacing preliminary study of a novel magnetic resonance imaging compatible polyetheretherketone mini-prosthesis for focal osteochondral defects

Journal of Orthopaedic Translation, 2021
Background: The use of partial articular resurfacing surgery with a mini-implant has been gradually increasing; the implant is mainly made of cobalt–chromium metal material, and cartilage changes cannot be monitored after implantation.
Xiangchao Meng, Wei Zhang, Zhiguo Yuan, Jun Chen, Zhuocheng Lyu, You Wang   +5 more
doaj   +1 more source

Stabilization of Damaged Articular Cartilage with Hydrogel‐Mediated Reinforcement and Sealing

Advanced Healthcare Materials, 2021
AbstractCartilage injuries and subsequent tissue deterioration impact millions of patients. Since the regeneration of functional hyaline cartilage remains elusive, methods to stabilize the remaining tissue, and prevent further deterioration, would be of significant clinical utility and prolong joint function.
Jay M. Patel, Claudia Loebel, Kamiel S. Saleh, Brian C. Wise, Edward D. Bonnevie, Liane M. Miller, James L. Carey, Jason A. Burdick, Robert L. Mauck   +8 more
openaire   +3 more sources

The Use of Allograft Tissue for Primary ACL Reconstruction is Associated with Increased Odds of Progression of Patellofemoral Articular Cartilage Damage Between Primary and Revision Surgery

Orthopaedic Journal of Sports Medicine, 2017
Objectives: Subsequent development of osteoarthritis remains a major problem following anterior cruciate ligament (ACL) injury and reconstruction. Progression of articular cartilage damage likely precedes clinical symptoms of osteoarthritis in these ...

doaj   +1 more source