Results 241 to 250 of about 139,262 (370)
New Advances of Degradable Magnesium‐Based Metal Biomaterials in the Field of Orthopedics
ABSTRACT Based on their outstanding biomechanical properties and superior osteogenic activity, magnesium (Mg) and its alloys have been extensively investigated for their biocompatibility and therapeutic efficacy in treating fractures and bone defects.
Jia‐Nan Yu +8 more
wiley +1 more source
Step‐Ladder Bioprinting to Align Collagen Fibers for Anisotropic Tissue Fabrication
The step‐ladder printing platform includes successive segments of channels with varying widths in a custom barrel design. This design allows for improved anisotropy of collagen fibers during extrusion. To demonstrate its effectiveness, corneal constructs with high transparency and shape fidelity, as well as articular cartilage constructs, displaying ...
Ilayda Namli +8 more
wiley +1 more source
Design of an injectable porous hydrogel modulating macrophages and their secreted EVs for joint defect repair in the pathology of rheumatoid arthritis. a) The solution containing HA and CS‐MOS, upon mixing with a crosslinker solution, undergoes porous hydrogel formation with the escape of generated CO₂ gas.
Anan Zhang +9 more
wiley +1 more source
Relationship Between Increased In Vivo Meniscal Loads and Abnormal Tibiofemoral Surface Alignment in ACL deficient Sheep is Varied [PDF]
Adeeb +45 more
core +2 more sources
Mechanosensitive Cell‐Laden Shape‐Memory Scaffolds Engineered via Cryogelation
GelMA‐based shape‐memory scaffolds encapsulating human adipose‐derived stem cells are fabricated via cryogelation, showing rapid recovery and high cell viability. Under cyclic compression, they promoted mechanotransduction gene expression, and composite formulations (collagen/GelMA, dECM/GelMA) retained robust shape‐memory, highlighting their promise ...
JaeYoon Lee +4 more
wiley +1 more source
Mechanism of ITGB2 in Osteoclast Differentiation in Osteoarthritis
In osteoclast precursors, higher ITGB1 than ITGB2 expression increases ITGA2‐ITGB1 integrin. In OA, extracellular signals upregulate ITGB2 and downregulate ITGB1, enhancing ITGA2‐ITGB2 integrin. This activates Rac1 to Rac‐GTP, driving osteoclast differentiation. Hyperactive subchondral osteoclasts accelerate OA progression.
Yang Yang +16 more
wiley +1 more source
SIRT-1 mediated regulation of ROβ stability influences protective mechanisms against articular cartilage damage 9143 [PDF]
Mi Ra Chang +4 more
openalex +1 more source

