Results 241 to 250 of about 139,262 (370)

Articular cartilage damage is frequently noted at the time of medial patellofemoral ligament reconstruction and is associated with age and patellofemoral anatomy

open access: gold
Robert A. Magnussen   +7 more
openalex   +1 more source

New Advances of Degradable Magnesium‐Based Metal Biomaterials in the Field of Orthopedics

open access: yesRare Metals, EarlyView.
ABSTRACT Based on their outstanding biomechanical properties and superior osteogenic activity, magnesium (Mg) and its alloys have been extensively investigated for their biocompatibility and therapeutic efficacy in treating fractures and bone defects.
Jia‐Nan Yu   +8 more
wiley   +1 more source

Step‐Ladder Bioprinting to Align Collagen Fibers for Anisotropic Tissue Fabrication

open access: yesSmall, EarlyView.
The step‐ladder printing platform includes successive segments of channels with varying widths in a custom barrel design. This design allows for improved anisotropy of collagen fibers during extrusion. To demonstrate its effectiveness, corneal constructs with high transparency and shape fidelity, as well as articular cartilage constructs, displaying ...
Ilayda Namli   +8 more
wiley   +1 more source

Mannose Oligosaccharide‐Conjugated In Situ Pore‐Forming Injectable Hydrogels for Rheumatoid Arthritis Treatment by Reprogramming Macrophage Extracellular Vesicles

open access: yesSmall Methods, EarlyView.
Design of an injectable porous hydrogel modulating macrophages and their secreted EVs for joint defect repair in the pathology of rheumatoid arthritis. a) The solution containing HA and CS‐MOS, upon mixing with a crosslinker solution, undergoes porous hydrogel formation with the escape of generated CO₂ gas.
Anan Zhang   +9 more
wiley   +1 more source

Relationship Between Increased In Vivo Meniscal Loads and Abnormal Tibiofemoral Surface Alignment in ACL deficient Sheep is Varied [PDF]

open access: yes, 2016
Adeeb   +45 more
core   +2 more sources

Mechanosensitive Cell‐Laden Shape‐Memory Scaffolds Engineered via Cryogelation

open access: yesSmall Structures, EarlyView.
GelMA‐based shape‐memory scaffolds encapsulating human adipose‐derived stem cells are fabricated via cryogelation, showing rapid recovery and high cell viability. Under cyclic compression, they promoted mechanotransduction gene expression, and composite formulations (collagen/GelMA, dECM/GelMA) retained robust shape‐memory, highlighting their promise ...
JaeYoon Lee   +4 more
wiley   +1 more source

Mechanism of ITGB2 in Osteoclast Differentiation in Osteoarthritis

open access: yesCell Proliferation, EarlyView.
In osteoclast precursors, higher ITGB1 than ITGB2 expression increases ITGA2‐ITGB1 integrin. In OA, extracellular signals upregulate ITGB2 and downregulate ITGB1, enhancing ITGA2‐ITGB2 integrin. This activates Rac1 to Rac‐GTP, driving osteoclast differentiation. Hyperactive subchondral osteoclasts accelerate OA progression.
Yang Yang   +16 more
wiley   +1 more source

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