Results 231 to 240 of about 43,162 (263)
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Minocycline reduces articular cartilage damage following osteochondral injury
The Knee, 2012Secondary injury pathways activated after chondral and osteochondral injury represent a potential target for therapies designed to minimize articular cartilage loss. The primary objective of this study was to test the potential chondroprotective effects of intra-articular minocycline following osteochondral injury.In vitro experiments were first ...
Akira, Yamamoto +2 more
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Piroxicam and poststeroidal damage of articular cartilage.
Roczniki Akademii Medycznej w Bialymstoku (1995), 1996The experiment was carried out in five groups of rats with 12 animals in each one. In three groups articular cartilage osteoarthrosis like damage was accomplished by intramuscular injection of Dexamethason once per week. The rest of animals with exception of the controls were given Piroxicam each day by gastric tube. In the group of rats receiving only
B, Lewandowski +4 more
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The possible role of neutrophil proteinases in damage to articular cartilage
Agents and Actions, 1978The proteolytic degradation of articular cartilage that is seen in the arthritides affects both of the major structural components of the tissue, proteoglycan and collagen. Neutrophil leucocytes are abundant in the synovial fluid of the inflamed joints, and we have considered whether the large quantities of neutral proteinases carried by these cells ...
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Arthritis & Rheumatism, 2003
AbstractObjectiveCartilage of young but skeletally mature dogs is more susceptible to blood‐induced damage than that of old dogs. The aim of the present study was to investigate whether cartilage of skeletally immature individuals is even more adversely affected by exposure to blood than that of mature individuals, as suggested by clinical practice ...
Michel J J, Hooiveld +5 more
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AbstractObjectiveCartilage of young but skeletally mature dogs is more susceptible to blood‐induced damage than that of old dogs. The aim of the present study was to investigate whether cartilage of skeletally immature individuals is even more adversely affected by exposure to blood than that of mature individuals, as suggested by clinical practice ...
Michel J J, Hooiveld +5 more
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Tribological assessment of hydrogels for replacing damaged articular cartilage
2021In joint disorders, lesions may be limited to the joint surface. In such cases, replacing only the affected surface to preserve healthy tissue and cancellous bone is preferable to total joint arthroplasty. By employing a cartilage replacement material in focal defect repair or hemiarthroplasty applications, joint stability may be preserved while ...
Doruk Baykal, Steven M. Kurtz
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Piroxicam and poststeroidal damage of articular cartilage
Advances in Medical Sciences, 1995<p>The experiment was carried out in five groups of rats with 12 animals in each one. In three groups articular cartilage osteoarthrosis like damage was accomplished by intramuscular injection of Dexamethason once per week. The rest of animals with exception of the controls were given Piroxicam each day by gastric tube.
Lewandowski, B. +3 more
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Bisphosphonates rescue articular cartilage from trauma damage
2015 41st Annual Northeast Biomedical Engineering Conference (NEBEC), 2015We previously found that systemic injection of zoledronic acid (ZA), a bisphosphonate, could suppress the post-traumatic osteoarthritis (PTOA) in meniscus dislocated animal model. The aim of this study is to explore the cellular and molecular mechanisms underlying ZA's chondro-protective function.
Yilu Zhou +3 more
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(iv) Treatment options for articular cartilage damage in the knee
Orthopaedics and Trauma, 2015Chondral damage within the knee of young patients remains a challenge to orthopaedic surgeons, with the chance of resulting mechanical symptoms limiting activity and the risk of progression to osteoarthritis. There are a number of different treatment options which utilize one of two principles for filling chondral defects: either bone marrow ...
James Donaldson +2 more
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Relationship between articular cartilage damage and bone density in the first metatarsal
The Journal of Foot and Ankle Surgery, 1998It is well known that bone changes occur in relationship to the articular cartilage damage seen in osteoarthritis. Numerous studies have shown a relationship between bone density and articular cartilage damage in knee and hip joints, but it is controversial as to whether or not an increased subchondral bone density results in greater cartilage damage ...
D, Bareither +6 more
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[Research on tissue engineered cartilage for repairing of articular cartilage damage and defects].
Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi, 2014Articular cartilage damage is very common in clinical practices. Due to the low self healing abilities of articular cartilage, it must be repaired or substituted by implants once natural articular cartilage is damaged. On the other hand, the various technologies currently used for healing damaged articular cartilage are little satisfactory, and rarely ...
Yusong, Pan, Guoxin, Ding, Jing, Wang
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