Results 221 to 230 of about 43,162 (263)

On mechanical mechanism of damage evolution in articular cartilage

Materials Science and Engineering: C, 2017
Superficial lesions of cartilage are the direct indication of osteoarthritis. To investigate the mechanical mechanism of cartilage with micro-defect under external loading, a new plain strain numerical model with micro-defect was proposed and damage evolution progression in cartilage over time has been simulated, the parameter were studied including ...
Yu-Tao, Men, Yan-Long, Jiang, Ling, Chen, Chun-Qiu, Zhang, Jin-Duo, Ye   +4 more
openaire   +2 more sources

Friction coefficients for mechanically damaged bovine articular cartilage

Biotechnology and Bioengineering, 2012
AbstractWe used a pin‐on‐disc tribometer to measure the friction coefficient of both pristine and mechanically damaged cartilage samples in the presence of different lubricant solutions. The experimental set up maximizes the lubrication mechanism due to interstitial fluid pressurization.
Liu, Shi, Daniel B, Brunski, Vassilios I, Sikavitsas, Matthew B, Johnson, Alberto, Striolo   +4 more
openaire   +2 more sources

Chondrocyte necrosis and apoptosis in impact damaged articular cartilage

Journal of Orthopaedic Research, 2001
AbstractA decrease in chondrocyte numbers is one characteristic of osteoarthritic cartilage. This decrease may be the result of apoptosis or other forms of cell death induced by mechanical damage. Furthermore, cell death may contribute to the structural and metabolic changes found in osteoarthritic cartilage.
C T, Chen, N, Burton-Wurster, C, Borden, K, Hueffer, S E, Bloom, G, Lust   +5 more
openaire   +2 more sources

Meniscal tears and articular cartilage damage in the dislocated knee

Knee Surgery, Sports Traumatology, Arthroscopy, 2015
Knee dislocations can cause significant damage to intra-articular knee structures, but currently there are limited data reporting articular cartilage and meniscal injuries in this setting. The purpose of this study is to (1) report the rate of concomitant intra-articular injuries at the time of multiligament reconstruction for knee dislocation, (2 ...
Aaron J, Krych, Paul L, Sousa, Alexander H, King, William M, Engasser, Michael J, Stuart, Bruce A, Levy   +5 more
openaire   +2 more sources

Hip morphology influences the pattern of articular cartilage damage

Knee Surgery, Sports Traumatology, Arthroscopy, 2014
AbstractPurposeThe aim of this study was to obtain data on chondral damage and compare the damage patterns of various hip disorders.MethodsData were collected at 100 consecutive arthroscopies, and chondral lesions were recorded on anatomic articular maps divided into different anatomical zones.
Mitsunori, Kaya, Tomoyuki, Suzuki, Makoto, Emori, Toshihiko, Yamashita   +3 more
openaire   +2 more sources

The Pathophysiology of Damage to Articular Cartilage

1976
In discussing the pathophysiology of damage to articular cartilage in the knee joint, we shall consider the etiologic factors and pathogenetic mechanisms that can account for damage to a joint surface with a previously healthy bony base and cartilaginous covering.
H. Cotta, W. Puhl
openaire   +1 more source

SERUM MARKERS OF ARTICULAR CARTILAGE DAMAGE AND REPAIR

Rheumatic Disease Clinics of North America, 1999
Joint cartilage is a dynamic tissue that reacts to trauma, inflammation, and other insults by attempting to repair its matrix. This reaction results in the release of cartilage macromolecules into the body fluids. Analysis of these fluids has identified a limited number of at least somewhat tissue-specific markers of altered cartilage metabolism ...
openaire   +2 more sources

THE ROLE OF NITRIC OXIDE IN ARTICULAR CARTILAGE DAMAGE

Rheumatic Disease Clinics of North America, 1999
The production of large amounts of NO in vitro by cytokine-activated chondrocytes has been established. In vitro studies suggest that NO compromises chondrocyte survival. The role of NO in regulating matrix biosynthesis and degradation has received much attention. Most studies indicate that NO is at least partly responsible for IL-1-induced suppression
openaire   +2 more sources

Active oxygen species, articular inflammation and cartilage damage

1992
Rheumatoid arthritis and osteoarthritis are age-related diseases, in which degenerative changes (arthrosis) and superimposed inflammatory reactions (arthritis) lead to progressive destruction of the joints. Active oxygen species derived from various sources play a role in this process, which may be influenced by appropriate treatment with antioxidants ...
Y, Henrotin, G, Deby-Dupont, C, Deby, P, Franchimont, I, Emerit   +4 more
openaire   +2 more sources

Ultrasonic damage assessment of articular cartilage for ultrasonic drug delivery

2013 IEEE International Ultrasonics Symposium (IUS), 2013
Osteoarthritis (OA) is a common musculoskeletal disease. There are drug therapies under development, but no localized way to transfer drugs into articular cartilage (AC). Previously we showed that 20 kHz high intensity ultrasound (HIU) can deliver micro- and nano-particles into AC [1]. However, at low frequencies, cavitation may occur.
C. Fridlund, V. Kananen, H. J. Nieminen, E. Haeggstrom   +3 more
openaire   +1 more source