Abstract Purpose The aim was to compare the safety profiles of corticosteroids (CS), hyaluronic acid (HA), blood‐derived products based on platelet concentrates (for simplicity indicated as PRP ‐ platelet‐rich plasma ‐ being PRP the most common product), and cell‐based therapies (namely products exploiting the therapeutic function of mesenchymal ...
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From mechanical triggering to metabolic-inflammatory driving: a new paradigm of knee osteoarthritis pathogenesis. [PDF]
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Study on the analgesic and anti-inflammatory mechanisms of Jingu Zhitong gel in the treatment of knee osteoarthritis through the IL-17, NGF-TrkA, and COX-2/PGE2 pathways. [PDF]
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Nanotherapeutic Strategies for Osteoarthritis: Targeting Aging, Metabolism and Inflammation. [PDF]
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Intrinsic Viscoelasticity of Type II Collagen Contributes to the Viscoelastic Response of Immature Bovine Articular Cartilage Under Unconfined Compression Stress Relaxation. [PDF]
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Synovial Fluid as a Window into Early Cartilage Remodeling After Autologous Matrix-Induced Chondrogenesis. [PDF]
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Collagen damage is not the cause of early softening in articular cartilage
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A phenomenological mathematical model of the articular cartilage damage
Computer Methods and Programs in Biomedicine, 2011Articular cartilage (AC) is a biological tissue that allows the distribution of mechanical loads and movement of joints. The presence of these mechanical loads influences the behavior and physiological condition of AC. The loads may cause damaged by fatigue through injuries due to repeated accumulated stresses.
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Computer simulation of damage on distal femoral articular cartilage after meniscectomies
Computers in Biology and Medicine, 2008It is commonly accepted that total or partial meniscectomies cause wear of articular cartilages that leads to severe damage in a period of few years. This also produces alteration of the biomechanical environment and increases articular instability, with a progressive and degenerative arthrosic pathology.
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