Results 31 to 40 of about 380,001 (247)

Implementation of a Convolutional Neural Network for Eye Blink Artifacts Removal From the Electroencephalography Signal

Frontiers in Neuroscience, 2022
Electroencephalography (EEG) signals are disrupted by technical and physiological artifacts. One of the most common artifacts is the natural activity that results from the movement of the eyes and the blinking of the subject.
Marcin Jurczak, Marcin Kołodziej, Andrzej Majkowski   +2 more
doaj   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Effects of stacking fault energies on the interaction between an edge dislocation and an 8.0-nm-diameter Frank loop of self-interstitial atoms

Nuclear Materials and Energy, 2016
Molecular dynamics simulations were conducted to investigate the effects of stacking fault energy (SFE) as a single variable parameter on the interaction between an edge dislocation and a Frank loop of self-interstitial atoms with a diameter of 8.0nm ...
S. Hayakawa, Y. Hayashi, T. Okita, M. Itakura, K. Suzuki, Y. Kuriyama   +5 more
doaj   +1 more source

Artefacts Commemorating the Battle of Varna in 1444

Sport i Turystyka, 2020
We just have the 575th anniversary of the memorable battle between a coalition of Christian armies and the army of the Ottoman Empire. Christians’ defeat had significant consequences not only for Bulgaria, but also for Byzantium and whole Europe. The aim
Lech Jaczynowski
doaj   +1 more source

Impact of Different Metal Artifact Reduction Techniques on Attenuation Correction of Normal Organs in ¹⁸F-FDG-PET/CT

Diagnostics, 2022
Purpose: To evaluate the impact of different metal artifact reduction algorithms on Hounsfield units (HU) and the standardized uptake value (SUV) in normal organs in patients with different metal implants.
Janna Morawitz, Ole Martin, Johannes Boos, Lino M. Sawicki, Katrin Wingendorf, Martin Sedlmair, Eduards Mamlins, Christina Antke, Gerald Antoch, Benedikt M. Schaarschmidt   +9 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Rules: A Toy Box

Phenomenology and Mind, 2020
“Induction provides a path to first principles” (Aristotle): so we approach our topic by sampling three distinct sorts of data—rules in actions as exemplified in games; rules as directives for manufacture; as laws not only for maintaining order among ...
Patrick Maynard
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Optimization of the pre-analytical stage of material processing for histochemical examination of skeletal muscle biopsies in the diagnosis of neuromuscular diseases

Нервно-мышечные болезни, 2019
Diagnosis of neuromuscular diseases is complicated by the variety of clinical manifestations and requires the use of additional methods, an important place among which is the pathomorphological study of skeletal muscle biopsy.
A. M. Sycheva, V. D. Nazarova, S. V. Lapin, M. G. Rybakova, D. I. Rudenko   +4 more
doaj   +1 more source