Results 41 to 50 of about 4,276,769 (250)

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias   +12 more
wiley   +1 more source

From carbon chemistry to silicon chemistry: a challenge for bioethics

open access: yesRevista Colombiana de Bioética, 2015
In the XXI century scientific advances seem to come from a science fiction story. They are so many and varied that we need huge quantities of paper, or to be consistent, countless e-books, bits of information, zeros and ones that can be translated ...
Edna Constanza Rodríguez Fernández
doaj   +1 more source

Use of mechanical ventilation in pediatric patients [PDF]

open access: yesVojnosanitetski Pregled, 2008
Background/Aim. Major aims of mechanical ventilation (MV) in pediatrics mean the contribution to complete recovery of acute disorder or to establishing stability of previously long-term changed health condition.
Martić Jelena   +6 more
doaj   +1 more source

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner   +6 more
wiley   +1 more source

Prototipo telemático de visión artificial para el reconocimiento de características en personas y vehículos

open access: yesVisión Electrónica, 2021
En un mundo cada vez más conectado con la tecnología y con la creciente necesidad de seguridad en todos los aspectos de la vida, surge este proyecto donde se abordará el problema de seguridad en los establecimientos educativos, pero que puede ser ...
Fanny Suárez-Mosquera   +2 more
doaj   +1 more source

Chalker scaling, level repulsion, and conformal invariance in critically delocalized quantum matter: Disordered topological superconductors and artificial graphene [PDF]

open access: yes, 2014
We numerically investigate critically delocalized wavefunctions in models of 2D Dirac fermions, subject to vector potential disorder. These describe the surface states of 3D topological superconductors, and can also be realized through long-range ...
Chou, Yang-Zhi, Foster, Matthew S.
core   +2 more sources

Decrypting cancer's spatial code: from single cells to tissue niches

open access: yesMolecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik   +4 more
wiley   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

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