Results 241 to 250 of about 1,114,729 (298)
Advanced Healthcare Materials, EarlyView.This review summarizes the roles of key central nervous system cell types, the extracellular matrix, and the blood‐brain barrier in neuroinflammation, and their integration into diverse 3D culture systems. It examines major incorporation strategies, including direct co‐culture, hydrogel encapsulation, transwell migration assays, and bioprinting ...
Emmanuelle D. Aiyegbusi +2 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.Neural cell–derived small extracellular vesicles (sEVs) are emerging as pivotal mediators in neurodegenerative diseases, exerting both pathogenic and therapeutic functions. This review synthesizes current evidence on how sEVs from distinct neural cell types regulate neurodegeneration, neuroprotection, biomarker discovery, and targeted drug delivery ...
Muhammad Waqas Salim +4 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.Implantable optoelectrical devices are an effective resource for the modulation and monitoring of neural activity with high spatiotemporal resolution. This review discusses current challenges faced by these devices and outlines future perspectives for the development of next‐generation neural interfaces targeting chronic, multisite, and multimodal ...
Stella Aslanoglou +4 more
wiley +1 more source
Artificial cells with viscoadaptive behavior based on hydrogel-loaded giant unilamellar vesicles. [PDF]
Chem SciLlopis-Lorente A +5 more
europepmc +1 more source
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Biosystems, 2004
After a survey of the theory and some realizations of self-replicating machines, this paper presents a novel self-replicating loop endowed with universal construction and computation properties. Based on the hardware implementation of the so-called Tom Thumb algorithm, the design of this loop leads to a new kind of cellular automaton made of a ...
Daniel, Mange +3 more
openaire +2 more sources
After a survey of the theory and some realizations of self-replicating machines, this paper presents a novel self-replicating loop endowed with universal construction and computation properties. Based on the hardware implementation of the so-called Tom Thumb algorithm, the design of this loop leads to a new kind of cellular automaton made of a ...
Daniel, Mange +3 more
openaire +2 more sources
Communicating artificial cells
Current Opinion in Chemical Biology, 2016Intercellular chemical communication is commonly exploited for the engineering of living cells but has been largely ignored by efforts to build artificial cells. Since communication is a fundamental feature of life, the construction of artificial cells capable of chemical communication will likely lead to a deeper understanding of biology and allow for
Lentini, Roberta +2 more
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Cytotherapy, 2003
Artificial T-cell receptors are generated by joining an Ag-recognizing domain (ectodomain) to the transmembrane and intracellular portion of a signaling molecule (endodomain). The ectodomain is most often derived from Ab variable chains, but may also be generated from T-cell receptor variable chains, as well as from other molecules. Various alternative
M, Pule, H, Finney, A, Lawson
openaire +2 more sources
Artificial T-cell receptors are generated by joining an Ag-recognizing domain (ectodomain) to the transmembrane and intracellular portion of a signaling molecule (endodomain). The ectodomain is most often derived from Ab variable chains, but may also be generated from T-cell receptor variable chains, as well as from other molecules. Various alternative
M, Pule, H, Finney, A, Lawson
openaire +2 more sources
Excitable Artificial Cells of Proteinoid
Applied Biochemistry and Biotechnology, 1984The proteinoid cells are assembled of thermal polymers of amino acids. Typically, an appropriate mixture of amino acids containing aspartic or glutamic acid is heated at 190 degrees C for 6 h, stirred with water for 2 h, dialyzed during 2 d, and lyophilized.
A T, Przybylski, S W, Fox
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Signal Transduction in Artificial Cells
Small Methods, 2023AbstractIn recent years, significant progress has been made in the emerging field of constructing biomimetic soft compartments with life‐like behaviors. Given that biological activities occur under a flux of energy and matter exchange, the implementation of rudimentary signaling pathways in artificial cells (protocells) is a prerequisite for the ...
Xiaolei Yu +3 more
openaire +2 more sources