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Signal Transduction in Artificial Cells
Small Methods, 2023AbstractIn recent years, significant progress has been made in the emerging field of constructing biomimetic soft compartments with life‐like behaviors. Given that biological activities occur under a flux of energy and matter exchange, the implementation of rudimentary signaling pathways in artificial cells (protocells) is a prerequisite for the ...
Xiaolei Yu +3 more
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Artificial Cells in Medicine and Biotechnology
Applied Biochemistry and Biotechnology, 1984Since the feasibility of artificial cells was first demonstrated in 1957 [Chang (1, 2)], an increasing number of approaches to their preparation and use have become available. Thus artificial cell membranes can now be formed using a variety of synthetic or biological materials to produce desired variations in their permeability, surface properties, and
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Artificial Cells for Cell and Organ Replacements
Artificial Organs, 2004Abstract: The artificial cell is a Canadian invention (Chang, Science, 1964). This principle is being actively investigated for use in cell and organ replacements. The earliest routine clinical use of artificial cells is in the form of coated activated charcoal for hemoperfusion for use in the removal of drugs, and toxins and waste in uremia and liver
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Artificial Cells for Dissecting Exocytosis
2022The fusion of vesicles and exocytosis release of neurotransmitters into the extracellular space for detection and chemical signal decoding by neighboring cells is the key process in neuronal communication. It is important to understand what regulates exocytosis because the amount of neurotransmitters released into the synaptic cleft has a direct impact
Yuanmo, Wang, Ann-Sofie, Cans
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An Artificial Cell Simulator based on Artificial Chemistry
Proceedings of the 2019 8th International Conference on Software and Computer Applications, 2019A cell is a basic building block of living beings. The knowledge about how a cell functions can be a very good source of inspiration for computer science to explore the origin of intelligence and rational behaviours. In this paper, we propose a simulator which supports artificial cell simulation based on artificial chemistry.
Chien-Le Goh +2 more
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Embryonics: Artificial Cells Driven by Artificial DNA
2001Embryonics is a long-term research project attempting to draw inspiration from the biological process of ontogeny, to implement novel digital computing machines endowed with better fault-tolerant capabilities. For this purpose FPGAs are extremely useful.
Prodan, L. +3 more
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Cytotherapy, 2003
Artificial T-cell receptors are generated by joining an Ag-recognizing domain (ectodomain) to the transmembrane and intracellular portion of a signaling molecule (endodomain). The ectodomain is most often derived from Ab variable chains, but may also be generated from T-cell receptor variable chains, as well as from other molecules. Various alternative
M, Pule, H, Finney, A, Lawson
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Artificial T-cell receptors are generated by joining an Ag-recognizing domain (ectodomain) to the transmembrane and intracellular portion of a signaling molecule (endodomain). The ectodomain is most often derived from Ab variable chains, but may also be generated from T-cell receptor variable chains, as well as from other molecules. Various alternative
M, Pule, H, Finney, A, Lawson
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Artificial assembly of a minimal cell
Molecular BioSystems, 2009Abstract Synthetic Biology approaches can assemble and/or reconstruct cell parts in synthetic compartments. A minimal cell as a model for early living cells can be artificially constructed in the laboratory resuming the main properties of a basic cell living system: a synthetic cell compartment or liposome to host a minimal metabolism
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Toward an "artificial cell" on a chip
Science, 2014DNA-driven biochemical reactions on a fabricated silicon chip recreate protein gradients and oscillations.
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Artificial Cells, Encapsulation, and Immobilization
Annals of the New York Academy of Sciences, 1999ABSTRACT: The basic principles of artificial cells, encapsulation and immobilization form the asisS for a number of bioartificial organs. Hemoperfusion based on encapsulated adsorbent has been in routine clinical uses for many years to remove toxins or drugs from the circulating blood.
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