Results 161 to 170 of about 1,485,663 (260)

Development of Peptide Nucleic Acid Based Artificial Ribonucleases, PNAzymes

, 2010
Since mRNA plays such a vital role in the transfer of genetic code from DNA to proteins, approaches involving interference with mRNA are of great interest for use in therapeutics. Amongst these, peptide nucleic acid based nuclease systems (PNAzymes) are being developed for in vivo gene silencing in future.
openaire   +1 more source

Palmitoylation of PSD‐95 Orchestrates Learning‐Dependent Metaplasticity in the Amygdala and Fear Memory

Advanced Science, Volume 13, Issue 52, 18 September 2026.
This study reveals that fear learning specifically triggers PICK1/DHHC2‐dependent palmitoylation of PSD‐95 in the lateral amygdala. Fear conditioning induces the dissociation of DHHC5 from PSD‐95 and the association of PSD‐95 with DHHC2. DHHC2‐mediated palmitoylation of PSD‐95 is required for synaptic transmission and underlies fear learning–induced ...
Zu‐Cheng Shen, Yu‐Xuan Weng, Zhi‐Xuan Xia, Yue‐Ling Zhao, Qian‐Qian Ding, Si‐Ying Wang, Ting Cao, Xuan‐Ying Chen, Wu‐Cheng Tao, Shen Lin, Zhou Chen, Yi‐Xiao Luo   +11 more
wiley   +1 more source

Editorial: Surviving and thriving: how crops perceive and respond to temperature stress, volume II. [PDF]

Front Plant Sci
Wang Z, Wang Y, Wong DCJ.
europepmc   +1 more source

Dielectric Elastomer Actuators as Safe and Effective Tools for Mechanostimulation of Human Cells

Advanced Intelligent Systems, Volume 8, Issue 9, September 2026.
Replicating physiological forces is crucial for realistic cell models. Dielectric elastomer actuators (DEAs) offer a soft alternative, though their high voltages raised toxicity concerns. We demonstrate that DEA stimulation causes no cell damage, cell death or cell‐cycle disruption, while activating mechanosensitive responses.
Simon Holzer, Chaimae Bahou, Noe Syfrig, Katia Monastyrskaya, Yoan Civet, Ali Hashemi Gheinani, Yves Perriard   +6 more
wiley   +1 more source

Breaking self-incompatibility for diploid hybrid potato breeding: advances, mechanisms, and emerging technologies. [PDF]

Front Plant Sci
Wang Y, Lin T, Wang Z, Fan L, Wang Y, Jiao X, Wang W, Zong X, Chen J, Yin Y.   +9 more
europepmc   +1 more source

Organelle Crosstalk and Metabolic Reprogramming in Idiopathic Pulmonary Fibrosis: Mechanisms and Therapeutic Implications

Cell Biochemistry and Function, Volume 44, Issue 9, September 2026.
ABSTRACT Idiopathic pulmonary fibrosis (IPF) is a fatal interstitial lung disease of unknown cause, marked by excessive deposition of extracellular matrix (ECM) components such as collagen. This pathological accumulation results in progressive destruction of the lung architecture and ultimately leads to respiratory failure.
Yining Zhang, Ling Teng, Limin Gong, Yuandong Fu, Minyi Qian   +4 more
wiley   +1 more source

Homage to James Feeney, a pioneer of biological NMR - Part II. [PDF]

Front Mol Biosci
Roberts GC.
europepmc   +1 more source

Cancer cell‐selective ectopic expression of CD20 as an antigen enables rituximab repurposing for solid tumour immunotherapy

Clinical and Translational Medicine, Volume 16, Issue 9, September 2026.
A recombinant AAV delivered tumour gene therapy. NF‐κB drives tumour‐selective antigen (e.g., CD20) expression. Ectopic CD20 enables rituximab repurposing to solid tumours. ADCC, ADCP, and CDC contribute to the antitumour activity. Abstract Background Despite the clinical success of cancer immunotherapies, their efficacy is often compromised by antigen‐
Ziyan Kong, Yile Wang, Yunqi Zhao, Lu Wang, Zhimin Fan, Yongqian Shu, Jinke Wang   +6 more
wiley   +1 more source

The ribonuclease E regulator RebA is essential for diazotrophic growth in the cyanobacterium <i>Anabaena</i> PCC 7120. [PDF]

mLife
Liu S, Wang Z, Lin G, Li W, Zeng X, Zhang JY, Zhang CC.   +6 more
europepmc   +1 more source

eDNA Analysis for Native Cavity‐Nesting Bee Ecology: A Comparison of Data From Brood Cells Contents and Larval DNA

Environmental DNA, Volume 8, Issue 5, September‐October 2026.
Artificial bee homes become eDNA reservoirs of insect, plant, fungal, and bacterial taxa providing a non‐invasive way to assess the ecology of wild bee larvae. ABSTRACT While the colonial honeybee is widely recognized by the public as a pollinator, thousands of native bees play an important but often under‐recognized role.
Katherine Lunn, Orianne Tournayre, Alejandro José Biganzoli‐Rangel, Nina R. Garrett, Maria L. Kuzmina, Nguyen Nguyen, Evgeny V. Zakharov, Dirk Steinke, Elizabeth L. Clare   +8 more
wiley   +1 more source