Results 171 to 180 of about 1,485,663 (260)

SiaRNA: a siamese neural network with bidirectional cross-attention for pairwise siRNA-mRNA efficacy prediction. [PDF]

Front Bioinform
Sapireddy V, Nathi R, Meruva VH, Nannapuraju VR, Basangari BC, Kondaparthi V.   +5 more
europepmc   +1 more source

(Science Monthly, 25: 048-051)Magic ribonuclease

, 2014
Liao, Y. D., J. F. Shaw
core  

mRNA Therapeutics Beyond Infectious Diseases: Expanding Therapeutic Applications and Future Perspectives

Immunity, Inflammation and Disease, Volume 14, Issue 9, September 2026.
Messenger RNA therapeutics are rapidly expanding beyond infectious diseases into oncology, autoimmune disorders, protein replacement therapy, cardiovascular and neurological diseases, and regenerative medicine. Advances in RNA engineering and targeted delivery are driving the development of safe, programmable, and precision therapeutics for diverse ...
Gedion Mengistu Dejen
wiley   +1 more source

Preliminary exploration of the relationship between ginsenoside content and endogenous hormones of multi stem ginseng and soil properties based on correlation analysis. [PDF]

Front Plant Sci
Chen Y, Xu Z, Qi W, Zhang T, Chen C, Shang X.   +5 more
europepmc   +1 more source

Strategies and mechanisms of precision genome engineering: From gene editing to genome writing

iMetaOmics, Volume 3, Issue 3, September 2026.
In this review, we examined the progression of genome manipulation from stochastic nuclease‐mediated cutting toward precise editing and programmable genome writing. We discussed tools like multi‐kilobase RNA‐guided integrators and Artificial Intelligence (AI)‐designed effectors and showed how these advances enable researchers to treat genomes as ...
Kerui Huang, Jianhong Tian, Wenyan Zhao, Siqin Zhang, Lixuan Xiang, Meiqing Yang, Lu Liu, Yazhou Huang, Ningyun Zhang, Lei Sun, Peng Xie, Nanyu Kuang, Hong Zhou, Chengfeng Qiu, Jun Yan, Xiaocheng Jiang, Qiang Tu, Yun Wang, Haoliang Hu, Youming Zhang   +19 more
wiley   +1 more source

False smut of rice: integrating molecular pathogenicity and epidemiology for next-generation disease management. [PDF]

Front Fungal Biol
Nishmitha K, Adhikari S, Mishra PK, Manik S, Lal HC, Dorjee L.   +5 more
europepmc   +1 more source

Integrated one‐pot CRISPR‐Cas detection: Addressing strategies and future prospects

Interdisciplinary Medicine, Volume 4, Issue 5, September 2026.
Integrated one‐pot CRISPR‐Cas detection significantly simplifies workflows, reduces cross‐contamination risks, and shortens turnaround times, making it highly suitable for point‐of‐care testing (POCT) and resource‐limited settings. Key challenges include system compatibility issues between Cas proteins and isothermal amplification, limited multiplexing
Jian Zhou, Xuemei Ren, Yingjie Ren, Ruiping Wu, Ruiman Geng, Le Chen, Zhuo Li   +6 more
wiley   +1 more source

Modern Optimization Strategies in High-Performance Liquid Chromatography Analysis. [PDF]

J Sep Sci
Elagamy SH, Elattar RH.
europepmc   +1 more source

Photo‐Activated microRNA 20a Delivery via Core‐Shell‐Shell Nanoparticles for the Suppression of Head and Neck Cancer

Journal of Biomedical Materials Research Part A, Volume 114, Issue 9, September 2026.
Graphical abstract depicting intracellular uptake of nanoparticles, near‐infrared light exposure, release of miRNA from nanoparticles, and proposed mechanistic action via the RNA induced silencing complex. ABSTRACT Current treatment modalities for head and neck cancer often leave patients with severe morbidities including difficulty swallowing ...
Angelica M. Helton, Tyus J. Yeingst, Lindsay P. Stone, Dylan P. Kearse, Neerav Goyal, Douglas B. Stairs, Daniel J. Hayes   +6 more
wiley   +1 more source

Natural Product‐Derived Vesicles in Nanotherapeutics

Journal of Extracellular Vesicles, Volume 15, Issue 9, September 2026.
Natural product‐derived vesicles (NPVs) are an emerging nature‐based nanotherapeutic that can deliver bioactive metabolites into the target site and induce beneficial mechanisms. A practical, chronological bench‐to‐bedside approach throughout the entire NPV development process is expected to resolve challenges encountered in NPV studies.
Kartiko Arif Purnomo, Tsong‐Long Hwang
wiley   +1 more source