Chronological profiling of early pregnancy transcripts in Murrah buffaloes. [PDF]
Srivastav A +7 more
europepmc +1 more source
Identification of Potential Vaccine Strains of Escherichia coli Isolates From Diarrhoeic Calves
This study aimed to identify vaccine candidate Escherichia coli strains isolated from diarrheic calves. Faecal samples collected from 500 calves were analysed, and E. coli strains were isolated and characterized phenotypically and genotypically. Antibiotic resistance profiles, virulence‐associated genes and MLVA genotyping were used to select 20 ...
Yasemin Erdoğan +16 more
wiley +1 more source
Identification of candidate nucleomodulins in ESKAPE bacteria - <i>in silico</i> prediction of bacterial proteins harboring canonical nuclear localization sequences. [PDF]
Riedl L +4 more
europepmc +1 more source
ABSTRACT MicroRNAs (miRNAs) have emerged as central regulators of pancreatic islet biology, influencing β‐cell development, proliferation, and function. In type 2 diabetes (T2D), both adaptive and maladaptive miRNA responses shape β‐cell compensation and progressive secretory dysfunction.
Lena Eliasson +3 more
wiley +1 more source
Investigation of carbohydrate-based molecules of <i>Theileria parva</i> parasites. [PDF]
Kolakowski J +6 more
europepmc +1 more source
Proteostasis ensures proper protein folding, modification, and degradation, while its impairment triggers ER stress. Chronic ER stress and maladaptive UPR via the CHOP–ERO1 axis remodel ERMCs, altering calcium signaling and mitochondrial metabolism.
Giorgia Maria Renna +5 more
wiley +1 more source
Artificial intelligence-driven design and optimization of mitochondria-targeted nanocarriers for chronic heart failure. [PDF]
Zhang Z, Zhou X, Wei T, Meng L, Long K.
europepmc +1 more source
Enhancing CRISPR‐Cas12a base editing in plants with LbCas12a variants and introns
Intron optimization of LbCas12a‐RRV improves cytosine and adenine base editing efficiency in plants, supports multiplexed and double‐strand break‐free genome modification, and expands precise genome engineering tools for crop breeding and plant functional research. ABSTRACT Cytosine base editors (CBEs) and adenine base editors (ABEs) are powerful tools
Yanhao Cheng +5 more
wiley +1 more source
Serum RNASE1 as a biomarker for disease activity and lupus nephritis in systemic lupus erythematosus. [PDF]
Xiao J +5 more
europepmc +1 more source
LRRK2 G2019S mutation is the most common genetic cause of Parkinson's disease but its contribution to nigrostriatal neurodegeneration, particularly in response to mitochondrial dysfunction, remains unclear. hLRRK2*G2019S transgenic mice exhibited early microglial activation and motor alterations, but not increased dopaminergic nigrostriatal ...
Roberto García‐Swinburn +8 more
wiley +1 more source

