Results 191 to 200 of about 1,485,663 (260)

Chronological profiling of early pregnancy transcripts in Murrah buffaloes. [PDF]

open access: yesVet Res Forum
Srivastav A   +7 more
europepmc   +1 more source

Identification of Potential Vaccine Strains of Escherichia coli Isolates From Diarrhoeic Calves

open access: yesVeterinary Medicine and Science, Volume 12, Issue 5, September 2026.
This study aimed to identify vaccine candidate Escherichia coli strains isolated from diarrheic calves. Faecal samples collected from 500 calves were analysed, and E. coli strains were isolated and characterized phenotypically and genotypically. Antibiotic resistance profiles, virulence‐associated genes and MLVA genotyping were used to select 20 ...
Yasemin Erdoğan   +16 more
wiley   +1 more source

MicroRNA‐Driven Regulation of β‐Cell Function in Type 2 Diabetes: Molecular Mechanisms, Network Insights, and Translational Perspectives

open access: yesActa Physiologica, Volume 242, Issue 9, September 2026.
ABSTRACT MicroRNAs (miRNAs) have emerged as central regulators of pancreatic islet biology, influencing β‐cell development, proliferation, and function. In type 2 diabetes (T2D), both adaptive and maladaptive miRNA responses shape β‐cell compensation and progressive secretory dysfunction.
Lena Eliasson   +3 more
wiley   +1 more source

Investigation of carbohydrate-based molecules of <i>Theileria parva</i> parasites. [PDF]

open access: yesFront Vet Sci
Kolakowski J   +6 more
europepmc   +1 more source

ER proteostasis meets mitochondrial function: contact sites as hubs of communication and therapeutic targets

open access: yesThe FEBS Journal, Volume 293, Issue 18, Page 5585-5599, September 2026.
Proteostasis ensures proper protein folding, modification, and degradation, while its impairment triggers ER stress. Chronic ER stress and maladaptive UPR via the CHOP–ERO1 axis remodel ERMCs, altering calcium signaling and mitochondrial metabolism.
Giorgia Maria Renna   +5 more
wiley   +1 more source

Enhancing CRISPR‐Cas12a base editing in plants with LbCas12a variants and introns

open access: yesJournal of Integrative Plant Biology, Volume 68, Issue 9, Page 3243-3259, September 2026.
Intron optimization of LbCas12a‐RRV improves cytosine and adenine base editing efficiency in plants, supports multiplexed and double‐strand break‐free genome modification, and expands precise genome engineering tools for crop breeding and plant functional research. ABSTRACT Cytosine base editors (CBEs) and adenine base editors (ABEs) are powerful tools
Yanhao Cheng   +5 more
wiley   +1 more source

Neuroinflammatory and Motor Alterations in LRRK2*G2019S Transgenic Mice Without Enhanced Vulnerability to Aging or Chronic MPTP‐Induced Nigrostriatal Neurodegeneration

open access: yesJournal of Neurochemistry, Volume 170, Issue 9, September 2026.
LRRK2 G2019S mutation is the most common genetic cause of Parkinson's disease but its contribution to nigrostriatal neurodegeneration, particularly in response to mitochondrial dysfunction, remains unclear. hLRRK2*G2019S transgenic mice exhibited early microglial activation and motor alterations, but not increased dopaminergic nigrostriatal ...
Roberto García‐Swinburn   +8 more
wiley   +1 more source

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