Results 21 to 30 of about 1,485,663 (260)
The RRM domain of poly(A)-specific ribonuclease has a noncanonical binding site for mRNA cap analog recognition [PDF]
, 2008 The degradation of the poly(A) tail is crucial for posttranscriptional gene regulation and for quality control of mRNA. Poly(A)-specific ribonuclease (PARN) is one of the major mammalian 3’ specific exo-ribonucleases involved in the degradation of the ...
Naohiro Kobayashi +25 more
core +2 more sources
Site-selective artificial ribonuclease using pinpoint RNA activation [PDF]
Nucleic Acids Symposium Series, 2001 An acridine residue attached to the end or the inside of a DNA activates the target phosphodiester linkages in complementary RNA. Due to this pinpoint activation, the RNA is site-selectively and efficiently cleaved at these linkages by various free metal ions under mild condition.
A, Kuzuya, R, Mizoguchi, M, Komiyama
openaire +2 more sources
Giraffe pantheatic ribonuclease [PDF]
, 1975 Comparative studies of proteins may not only provide inforrnatlon on the evolutlon, but also on the structure function relationship of these proteins. Here the isolation and purification of the ribonuclease from giraffe pancreas is reported.
Gaastra, Willem, Gaastra, Willem,
core +7 more sources
Construction of Ribonuclease-Decorated Artificial Virus-like Capsid by Peptide Self-assembly [PDF]
Artificial virus-like capsids decorated with ribonuclease S (RNase S) on their exterior were constructed by the self-assembly of β-annulus-S-peptide and the interaction between S-peptide moiety and S-protein.
Matsuura, Kazunori +17 more
core +1 more source
The compactness of ribonuclease A and reduced ribonuclease A [PDF]
, 1998 The compactness of ribonuclease A with intact disulfide bonds and reduced ribonuclease A was investigated by synchrotron small-angle X-ray scattering. The Rg values and the Kratky plots showed that non-reduced ribonuclease A maintain a compact shape with
Fan, Ying-Xin +9 more
core +1 more source
Identification and analysis of S-genotypes in 23 new pear cultivars [PDF]
Guoshu xuebao[Objective] Taxonomically, pear (Pyrus spp.) belongs to the Rosaceae family, Maloideae subfamily and Pyrus genus. It exhibits a typical gametophytic self-incompatibility (GSI) mechanism controlled by a single S-locus with multiple alleles.
WANG Yanan +5 more
doaj +1 more source
CHIMIA, 2001 Chemically modified oligonucleotides serve as tools in fundamental research as diagnostic reagents and pharmaceutical compounds. Various chemical groups can nowadays be linked to oligonucleotides, In particular, synthetic constructs of oligonucleotides and lanthanide complexes can serve as artificial ribonucleases.
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Design and Synthesis of Peptide-Oligonucleotide Conjugates as Potential Artificial Ribonucleases [PDF]
Nucleic Acids Symposium Series, 2008 A series of peptide-oligonucleotide conjugates was synthesized. The peptide fragment was attached to the middle part of DNA sequence. For this purpose the new amidophosphite dC with linker at C5-position was synthesized.
Inna, Serpokrylova +4 more
openaire +2 more sources
Towards artificial ribonucleases: the sequence-specific cleavage of RNA in a duplex [PDF]
Nucleic Acids Research, 1996 Lanthanide complexes covalently attached to oligonucleotides have been shown to cleave RNA in a sequence-specific manner. Efficient cleavage, however, is at present limited to single-stranded RNA regions, as RNA in a duplex is considerably more resistant to strand scission.
J, Hall, D, Hüsken, R, Häner
openaire +2 more sources
Synthetic in vitro transcriptional oscillators
Molecular Systems Biology, 2011 The construction of synthetic biochemical circuits from simple components illuminates how complex behaviors can arise in chemistry and builds a foundation for future biological technologies.
Jongmin Kim, Erik Winfree
doaj +1 more source