Results 21 to 30 of about 467,084 (261)
Frontiers in Genetics, 2019 Domestication of Atlantic salmon started approximately 40 years ago, using artificial selection through genetic improvement programs. Selection is likely to have imposed distinctive signatures on the salmon genome, which are often characterized by high ...
María Eugenia López +7 more
doaj +1 more source
Philosophies, 2021 The nineteenth century was a time of great economic, social, and political change. The population of a modernizing Europe began demanding more freedom, which in turn propelled the ongoing discussion on the philosophy of nature.
Péter Poczai +3 more
doaj +1 more source
From Evolutionary Aspects of Zoophytophagy to Biological Control
Frontiers in Ecology and Evolution, 2018 Zoophytophagy (true omnivory) is a ubiquitous behavior. It allows plant-feeding predators to maximize their development by finding essential nutrients, and to survive when animal resources are scarce. In agroecosystems, some zoophytophagous predators are
François Dumont +3 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
G3: Genes, Genomes, Genetics, 2016 Domesticated species are often composed of distinct populations differing in the character and strength of artificial and natural selection pressures, providing a valuable model to study adaptation.
Małgorzata Pilot +9 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Review: Balancing Selection for Deleterious Alleles in Livestock
Frontiers in Genetics, 2021 Harmful alleles can be under balancing selection due to an interplay of artificial selection for the variant in heterozygotes and purifying selection against the variant in homozygotes.
Martijn F. L. Derks +2 more
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Frontiers in Microbiology, 2018 The extraction and processing of uranium (U) have polluted large areas worldwide, rendering anthropogenic extreme environments inhospitable to most species.
Beatriz Baselga-Cervera +4 more
doaj +1 more source