Results 71 to 80 of about 1,559,905 (290)
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source
IntroductionThe composite breed Brangus combines the resilience and adaptability of the Bos t. indicus breed Brahman with the superior meat quality and fertility traits of the Bos t. taurus breed Angus.
Gabriel A. Zayas, Raluca G. Mateescu
doaj +1 more source
Interactions between Behaviour and Genetics in Wild and Domestic Bird Populations [PDF]
Personality traits can be favoured by both natural and artificial selection, if they result in increased fitness or productivity, and therefore play an important role in both wild and domestic populations.
Oers, K., van, Rodenburg, T.B.
core +1 more source
Inbreeding in artificial selection programmes
In a population under artificial selection, the effective population size may be less than the actual number of parents selected because there will be variation between families in the character under selection and consequently in the probability of selection.
openaire +3 more sources
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel +4 more
wiley +1 more source
Composite crosses result from the mating of two or more distinct cattle breeds. Breeding performance may improve rapidly using a well-organized composite breeding system and a clear selection index.
Mohd Jaafar +2 more
doaj +1 more source
The Survival of Market Orientation through Artificial Selection
Observations of a Japanese automobile dealer company shifting from a selling orientation to a market orientation revealed the following: (1) A market-oriented program with a process and team orientation threatened the self-concept of the sales force and ...
Ryusuke KOSUGE, Nobuo TAKAHASHI
doaj +1 more source
Variation of seed characteristic from natural and artificial selection in the genus Papaver [PDF]
Papaveraceae is a mediterranean plant family with an important scientific, commercial and ethnobotanical interest. Includes wild species, which are distributed throughout the Spanish territory, as Papaver rhoeas, P. dubium, P. bracteatum, P. hybridum and
Martín-Clemente, Elena +1 more
core

