Results 11 to 20 of about 44,340 (259)

Tailoring the effect of antithrombin-targeting therapy in haemophilia A using in silico thrombin generation

Scientific Reports, 2021
Factor (F) VIII deficiency causes bleeding in haemophilia A patients because of the reduced formation of procoagulant enzyme thrombin, which is needed to make the blood clot.
Romy M. W. de Laat-Kremers, Marisa Ninivaggi, Iris van Moort, Moniek de Maat, Bas de Laat   +4 more
doaj   +1 more source

Coagulation parameters predict COVID-19-related thrombosis in a neural network with a positive predictive value of 98%

Frontiers in Immunology, 2022
Thrombosis is a major clinical complication of COVID-19 infection. COVID-19 patients show changes in coagulation factors that indicate an important role for the coagulation system in the pathogenesis of COVID-19.
Romy de Laat-Kremers, Raf De Jongh, Raf De Jongh, Marisa Ninivaggi, Aernoud Fiolet, Rob Fijnheer, Jasper Remijn, Bas de Laat, Bas de Laat   +8 more
doaj   +1 more source

Increased BMI and Blood Lipids Are Associated With a Hypercoagulable State in the Moli-sani Cohort

Frontiers in Cardiovascular Medicine, 2022
The coagulation system can be assessed by the thrombin generation (TG) assay, and increased TG peak height, endogenous thrombin potential (ETP), and velocity index are associated with an increased risk of thrombosis. Obesity had been reported to increase
Romy de Laat-Kremers, Augusto Di Castelnuovo, Lisa van der Vorm, Simona Costanzo, Marisa Ninivaggi, Chiara Cerletti, Dana Huskens, Dana Huskens, Amalia De Curtis, Alessandro Gialluisi, Alessandro Gialluisi, Cuicui Bai, Cuicui Bai, Giovanni de Gaetano, Dongmei Yin, Maria Benedetta Donati, Bas de Laat, Bas de Laat, Bas de Laat, Licia Iacoviello, Licia Iacoviello, The Moli-sani Investigators   +21 more
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Memristive Artificial Synapses for Neuromorphic Computing [PDF]

Nano-Micro Letters, 2021
AbstractNeuromorphic computing simulates the operation of biological brain function for information processing and can potentially solve the bottleneck of the von Neumann architecture. This computing is realized based on memristive hardware neural networks in which synaptic devices that mimic biological synapses of the brain are the primary units ...
Wen Huang, Xuwen Xia, Chen Zhu, Parker Steichen, Weidong Quan, Weiwei Mao, Jianping Yang, Liang Chu, Xing’ao Li   +8 more
openaire   +3 more sources

Abacavir use is associated with increased prothrombin conversion

Frontiers in Immunology, 2023
There is ongoing debate as to whether abacavir (ABC) increases the risk for cardiovascular disease(CVD) in people living with HIV (PLHIV) and the mechanisms underlying this possible association.
Qiuting Yan, Qiuting Yan, Shengshi Huang, Shengshi Huang, Wouter van der Heijden, Marisa Ninivaggi, Lisa van de Wijer, Romy de Laat-Kremers, Andre J. Van der Ven, Bas de Laat, Bas de Laat, Quirijn de Mast   +11 more
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Artificial optoelectronic synaptic characteristics of Bi2FeMnO6 ferroelectric memristor for neuromorphic computing

Materials & Design, 2022
Photoelectric synapse is a new type of artificial synapse that combines light pulse excitation and electrical pulse excitation, and is an important component for the development of neuromorphic hardware.
Wen-Min Zhong, Xin-Gui Tang, Qiu-Xiang Liu, Yan-Ping Jiang   +3 more
doaj   +1 more source

Artificial Synapses: Organometal Halide Perovskite Artificial Synapses (Adv. Mater. 28/2016) [PDF]

Advanced Materials, 2016
A synapse-emulating electronic device based on organometal halide perovskite thin films is described by T.-W. Lee and co-workers on page 5916. The device successfully emulates important characteristics of a biological synapse. This work extends the application of organometal halide perovskites to bioinspired electronic devices, and contributes to the ...
Wentao, Xu, Himchan, Cho, Young-Hoon, Kim, Young-Tae, Kim, Christoph, Wolf, Chan-Gyung, Park, Tae-Woo, Lee   +6 more
openaire   +2 more sources

Artificial SiN_z:H Synapse Crossbar Arrays with Gradual Conductive Pathway for High-Accuracy Neuromorphic Computing

Nanomaterials, 2023
Inspired by its highly efficient capability to deal with big data, the brain-like computational system has attracted a great amount of attention for its ability to outperform the von Neumann computation paradigm. As the core of the neuromorphic computing
Tong Chen, Zhongyuan Ma, Hongsheng Hu, Yang Yang, Chengfeng Zhou, Furao Shen, Haitao Xu, Jun Xu, Ling Xu, Wei Li, Kunji Chen   +10 more
doaj   +1 more source

Synaptic plasticity and preliminary-spike-enhanced plasticity in a CMOS-compatible Ta2O5 memristor

Materials & Design, 2020
An artificial synapse that can perform both learning and memory functions was realized using an amorphous Ta2O5 memristor. A Pt/Ta2O5/TiN memristor, with an amorphous Ta2O5 film grown at 100 °C, exhibited reliable bipolar switching properties at the ...
Hyun–Gyu Hwang, Jong–Un Woo, Tae–Ho Lee, Sung-Mean Park, Tae–Gon Lee, Woong-Hee Lee, Sahn Nahm   +6 more
doaj   +1 more source

Memristive artificial synapses based on Au–TiO2 composite thin film for neuromorphic computing

APL Materials, 2023
Neuromorphic computing architecture is considered to be a highly desirable next-generation computing architecture as it simulates the way the brain processes information.
Haonan Zhu, Zhenxun Tang, Guoliang Wang, Yuan Fang, Jijie Huang, Yue Zheng   +5 more
doaj   +1 more source