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Binding profile of Artocarpus integrifolia agglutinin (Jacalin)
Life Sciences, 2003Artocarpus integrifolia agglutinin (Jacalin) from the seeds of jack fruits has attracted considerable attention for its diverse biological activities and has been recognized as a Galbeta1-->3GalNAc (T) specific lectin. In previous studies, the information of its binding was limited to the inhibition results of monosaccharides and several T related ...
Albert M, Wu +4 more
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Oral allergy syndrome to jackfruit (Artocarpus integrifolia)
Allergy, 1997A 30‐year‐old man from the Philippines with pollen allergy noted the appearance of oral allergy syndrome (OAS) after eating raw apple, raw peach, raw celery, and, recently, jackfruit (Artocarpus integrifolia), a tropical fruit which belongs to the Moraceae family (mulberry) and to the genus Artocarpus (breadfruit tree).
Wüthrich B, Borga A, Yman L
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Ricinoleic acid inArtocarpus integrifolia seed oil
Journal of the American Oil Chemists' Society, 1989AbstractSeed oil ofArtocarpus integrifolia syn.Artocarpus heterophyllus belonging to the Moraceae family contains a small amount of ricinoleic acid (7.2%). The identification was made on the basis of TLC, IR, NMR, MS and chemical degradation. The major components of the oil are linoleic acid (40.2% and palmitic acid (30.2%).
C. D. Daulatabad, A. M. Mirajkar
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A crude extract of Artocarpus integrifolia contains two lectins with distinct biological activities
Immunology Letters, 1992The crude extract derived from seeds of Artocarpus integrifolia (jack fruit) contains two fractions with different biological activities for lymphocytes. One fraction is the D-galactose-binding lectin, jacalin, obtained by affinity purification on a D-galactose agarose column.
I K, de Miranda-Santos +4 more
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Biophysical Chemistry, 1999
The KM+ lectin exhibits a novel and unusual circular dichroism (CD) spectrum that could be explained by a high proline content that would be inducing deformation of the beta-structure and/or unusual turns. KM+ was shown to be a very rigid lectin, which was very stable under a broad variety of conditions (urea, guanidine, hydrolysis, pH, etc.).
R A, Silva-Lucca +4 more
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The KM+ lectin exhibits a novel and unusual circular dichroism (CD) spectrum that could be explained by a high proline content that would be inducing deformation of the beta-structure and/or unusual turns. KM+ was shown to be a very rigid lectin, which was very stable under a broad variety of conditions (urea, guanidine, hydrolysis, pH, etc.).
R A, Silva-Lucca +4 more
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Biochimica et Biophysica Acta (BBA) - General Subjects, 2005
KM+, a mannose-binding lectin present in the seeds of Artocarpus integrifolia, has interesting biological properties and potential pharmaceutical use [A. Panunto-Castelo, M.A. Souza, M.C. Roque-Barreira, J.S. Silva, KM(+), a lectin from Artocarpus integrifolia, induces IL-12 p40 production by macrophages and switches from type 2 to type 1 cell-mediated
Luis L P, daSilva +6 more
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KM+, a mannose-binding lectin present in the seeds of Artocarpus integrifolia, has interesting biological properties and potential pharmaceutical use [A. Panunto-Castelo, M.A. Souza, M.C. Roque-Barreira, J.S. Silva, KM(+), a lectin from Artocarpus integrifolia, induces IL-12 p40 production by macrophages and switches from type 2 to type 1 cell-mediated
Luis L P, daSilva +6 more
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Biochemical and Biophysical Research Communications, 1995
Treatment of the human erythroleukemia cell line K562 with the galactose-binding lectin, jacalin, results in rapid and profound alterations in the morphology and biochemistry of the cells. Within minutes of lectin addition, the cells adhere to the plastic tissue culture surface, and within hours, the cells spread on the surface, acquiring a monocyte ...
M, Yagi, A, Campos-Neto, K, Gollahon
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Treatment of the human erythroleukemia cell line K562 with the galactose-binding lectin, jacalin, results in rapid and profound alterations in the morphology and biochemistry of the cells. Within minutes of lectin addition, the cells adhere to the plastic tissue culture surface, and within hours, the cells spread on the surface, acquiring a monocyte ...
M, Yagi, A, Campos-Neto, K, Gollahon
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Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2015
The advances in nanomedicine demonstrate the anticancer properties of silver nanoparticles (AgNPs) and considered as an alternative to the available chemotherapeutic agents. Owing to the preferential interaction of Artocarpus integrifolia lectin (jacalin) with Galβ1-3GalNAcα (a chemically well-defined tumor associated antigen), a study was undertaken ...
Khan Behlol, Ayaz Ahmed +2 more
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The advances in nanomedicine demonstrate the anticancer properties of silver nanoparticles (AgNPs) and considered as an alternative to the available chemotherapeutic agents. Owing to the preferential interaction of Artocarpus integrifolia lectin (jacalin) with Galβ1-3GalNAcα (a chemically well-defined tumor associated antigen), a study was undertaken ...
Khan Behlol, Ayaz Ahmed +2 more
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Subcellular distribution of jacalin in Artocarpus integrifolia seed.
Cytobios, 1997Seeds of Artocarpus integrifolia (jack fruit) contain large amounts of the anti-T lectin, jacalin. The mature seeds of jack fruit were homogenized in 0.25 M sucrose and separated by differential centrifugation into four fractions, viz wall, intermediate, and microsomal pellets and soluble supernatant.
M, Majumder, B P, Chatterjee
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