Results 291 to 300 of about 538,570 (408)

Enantiomerically Enriched Aziridine‐2‐carboxylates via Copper‐Catalyzed Reductive Kinetic Resolution of 2H‐Azirines

Angewandte Chemie, EarlyView.
Kinetic resolution by copper hydride catalyzed reduction of 2H‐azirines secured optically enriched N‐H aziridine‐2‐carboxylates with excellent diastereoselectivity (>20:1) and good enantioselectivity (up to 94% ee). DFT calculations and non‐covalent interaction analysis established the reaction pathway and revealed two key non‐covalent interactions ...
Yinuo Zheng, Elvis Wang Hei Ng, Antonio Rizzo, Pauline Chiu   +3 more
wiley   +1 more source

Thermally accelerated Heck reaction under direct mechanocatalysis using palladium milling balls.

RSC Mechanochem
Templ J, Hwang S, Schwemin T, Baltaci H, Borchardt L.   +4 more
europepmc   +1 more source

Osmium(IV) Tetraaryl Complexes Formed from Prefunctionalized Ligands. [PDF]

Inorg Chem
Olivar C, Parr JM, Avedian C, Saal T, Zagami L, Haiges R, Sharma M, Inkpen MS.   +7 more
europepmc   +1 more source

Macrocyclic dizinc(II) alkyl and alkoxide complexes: Reversible CO2 uptake and polymerization catalysis testing [PDF]

, 2015
Bennington, M, Brooker, S, Romain, C, White, AJP, Williams, CK   +4 more
core   +1 more source

Total Synthesis of Pyrrolnitrin. II. Synthesis of Ethyl 3-Aryl-5-methyl-2-pyrrolecarboxylate. (1)

, 1969
Hiroshi Nakano, Suminori Umio, Kazuo Kariyone, Kunihiko Tanaka, I. Ueda, Hitoshi Nakamura   +5 more
openalex   +2 more sources

Synthesis and Characterization of Photoswitchable Covalent Ligands for the β2‐Adrenoceptor

Angewandte Chemie, EarlyView.
A structure‐based design of a covalent photoswitchable ligand for the β2‐adrenergic receptor, a therapeutically relevant GPCR, is described. This tool facilitates the modification of the intrinsic activity of the protein by light. Computational analysis of its mechanism of action suggests that the photoswitch takes place within the binding pocket ...
Ulrike Wirth, Eduard Neu, Davide Provasi, Steffen Feustel, Maximilian F. Schmidt, Harald Hübner, Dorothée Weikert, Marta Filizola, Burkhard König, Peter Gmeiner   +9 more
wiley   +1 more source

Evidence for a Unifying Ni^I/Ni^III Mechanism in Light-Mediated Cross-Coupling Catalysis. [PDF]

J Am Chem Soc
Anghileri L, Baunis H, Bena AR, Giannoudis C, Burke JH, Reischauer S, Merschjann C, Wallick RF, Al Said T, Adams CE, Simionato G, Kovalenko S, Dell'Amico L, van der Veen RM, Pieber B.   +14 more
europepmc   +1 more source

Total Synthesis of Pyrrolnitrin. IV. Synthesis of Ethyl 3-Aryl-5-methyl-2-pyrrolecarboxylate. (3)

, 1969
SUMINORI UMIO, KAZUO KARIYONE, KUNIHIKO TANAKA, Hideyo Noguchi   +3 more
openalex   +2 more sources

Engineered Biocatalyst for Enantioselective Hydrazone Reduction

Angewandte Chemie, EarlyView.
Here, we report the discovery and engineering of a hydrazone reductase (HRED) biocatalyst that promotes efficient reduction of protected hydrazones with exceptional stereocontrol. These biotransformations offer a sustainable strategy for synthesizing valuable chiral N─N containing products that are commonly found in pharmaceuticals and agrochemicals ...
Amy E. Hutton, Fei Zhao, Elizabeth Ho, Jack Domenech, Vanessa Harawa, Murray J. B. Brown, Gideon Grogan, Phillip D. Clayman, Nicholas J. Turner, Anthony P. Green   +9 more
wiley   +1 more source

Design and Evaluation of Bivalent K-Ras Inhibitors That Target the CAAX Binding Site and the Acidic Surface of Farnesyltransferase and Geranylgeranyltransferase I. [PDF]

Chemistry
Horiuchi N, Omer R, Sugino F, Ogino N, Inoue Y, Aslamuzzaman K, Suzuki T, Sebti SM, Ohkanda J.   +8 more
europepmc   +1 more source