Results 101 to 110 of about 1,983,941 (246)

Aryl hydrocarbon receptor (AhR) is regulated by hyperoxia in premature infants

The Journal of Maternal-Fetal & Neonatal Medicine
To investigate whether aryl hydrocarbon receptor (AhR) is involved in hyperoxia-mediated oxidative stress by observing the relationship between AhR and reactive oxygen species (ROS) in peripheral blood mononuclear cells (PBMCs) after oxygen exposure in premature infants.After 48 h of oxygen inhalation at different concentrations, discarded peripheral ...
Xi, Yang, Xia, Wang, Wenbin, Dong
openaire   +2 more sources

Updates in acute graft‐versus‐host disease: From novel pathogenic mechanisms to emerging therapeutic targets

British Journal of Haematology, EarlyView.
The graphical abstract provides a view on selected aspects of the pathogenesis, risk stratification and treatment of acute GVHD. Summary Acute graft‐versus‐host disease (aGVHD) remains a major complication following allogeneic haematopoietic stem cell transplantation (allo‐HSCT), representing a leading cause of non‐relapse mortality (NRM) and ...
Hazim Khatib, Robert Zeiser
wiley   +1 more source

3‐Indoxyl Sulfate and O‐Acetylcarnitine Are Potential Novel Biomarkers for Early Diagnosis of Esophageal Cancer

Cancer Science, EarlyView.
Through comprehensive analysis of plasma and urine from patients with esophageal cancer and healthy controls, 3‐indoxyl sulfate and O‐acetylcarnitine were identified as metabolites significantly associated with esophageal cancer. These metabolites were elevated in patients and demonstrated promising diagnostic performance for early detection.
Kenji Hamada, Yohei Ozawa, Hiroshi Okamoto, Shinji Fukuda, Tomoyoshi Soga, Takaaki Abe, Hozumi Motohashi, Shohei Murakami, Takashi Kamei   +8 more
wiley   +1 more source

Indoleamine 2,3‐Dioxygenase 1 as an Adjunctive Histopathological Marker of Cholangitis Activity in Primary Biliary Cholangitis

Hepatology Research, EarlyView.
IDO‐1 immunostaining identifies primary biliary cholangitis even in morphologically subtle bile duct lesions. IDO‐1 expression reflects cholangitis activity and is suppressed by ursodeoxycholic acid treatment, indicating its value as a dynamic diagnostic adjunct rather than a static marker of chronic damage.
Kaori Yoshimura, Shinji Shimoda, Ryoka Masuda, Tram Nguyen Thi, Rui Yang, Quynh Nguyen Thi, Dong Le Thanh, Yuko Tamano, Yasunori Sato, Taro Yamashita, Kenichi Harada   +10 more
wiley   +1 more source

Attenuation of microglial aryl hydrocarbon receptor alters astrocyte activation and chronic pain sensitization in aging

Open Life Sciences
This study aims to examine differences in aryl hydrocarbon receptor (AHR) expression between microglia in aged and adult mice and to investigate the impact of microglial AHR attenuation on chronic pain sensitization.
Sun Jia-Xiao, Huang Ying, Zheng Juan-Juan, Xie Wen-Qin   +3 more
doaj   +1 more source

Trans‐resveratrol alleviates inflammation and improves skin barrier function via aryl hydrocarbon receptor pathway in human reconstructed epidermis

International Journal of Cosmetic Science, EarlyView.
In a cytokine‐challenged human epidermal model, trans‐resveratrol reduces inflammation (IL‐1α) and oxidative stress markers (CYP1A1, CYP1B1), while modulating the expression of barrier‐related genes (LOR, OCLN) and differentiation‐associated CASP14. This supports its role as a multifunctional active for sensitive and compromised skin.
Irini M. Dijkhoff, Sandeep Keshavan, Regina G. Daré, Alke Petri‐Fink, Marc Eeman, Agnès Tessier, Barbara Rothen‐Rutishauser   +6 more
wiley   +1 more source

Aryl hydrocarbon receptor (AHR) [PDF]

Science-Business eXchange, 2010
openaire   +3 more sources

Crosstalk between Aryl Hydrocarbon Receptor and Glucocorticoid Receptor in Human Retinal Pigment Epithelial Cells

International Journal of Endocrinology, 2017
The aryl hydrocarbon receptor (AHR) is known to mediate the cellular reaction involved in processing environmental contaminants and, ultimately, preventing accumulation of unfavorable extra lipids and proteins.
Hong Lan Jin, Yujin Choi, Kwang Won Jeong   +2 more
doaj   +1 more source

Pretreatment of keratinocytes with Galactomyces ferment filtrate (GFF) promotes stress resiliency in an in vitro oxidative stress model

International Journal of Cosmetic Science, EarlyView.
GFF pretreatment enhances keratinocyte protection against oxidative stress by mitigating stress‐induced biomolecular changes and gene expression dysregulation. GFF‐pretreated keratinocytes maintain healthy epidermal biology post‐stress, preserving mitochondrial function and proliferative capacity.
Lisa C. Green, Tim Reichling, Holly A. Rovito, Jodie Reed, Xingtao Wei, John M. Snowball, Tom Cambron, Tomohiro Hakozaki   +7 more
wiley   +1 more source

The aryl hydrocarbon receptor: a new frontier in male reproductive system

Reproductive Biology and Endocrinology
Background The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor historically recognized for its role in the regulation of toxicity mediated by environmental chemicals.
Ghadeer Bustani, Hasan Alghetaa, Amira Mohammed, Mitzi Nagarkatti, Prakash Nagarkatti   +4 more
doaj   +1 more source