Results 171 to 180 of about 11,887 (214)

Identification of functional aryl hydrocarbon receptor and aryl hydrocarbon receptor nuclear translocator in murine splenocytes

Biochemical Pharmacology, 1996
The objective of the present studies was to determine whether the aryl hydrocarbon receptor (AhR) and AhR nuclear translocator (ARNT) protein are present and functional in B6C3F1 (C57BL/6 x C3H) mouse splenocytes. Northern analysis of poly(A) RNA isolated from splenocytes revealed transcripts of approximately 6.6 kb which hybridized to the AhR ...
C E, Williams   +3 more
openaire   +2 more sources

Expression of aryl hydrocarbon receptor and aryl hydrocarbon receptor nuclear translocators in human adenoid tissue

Auris Nasus Larynx, 2011
The aim of this study was to determine whether aryl hydrocarbon receptor (AhR) and AhR nuclear translocators (ARNTs) are expressed in human adenoid tissue.Paraffin-embedded human adenoid tissue specimens were obtained from eight children with adenoid hypertrophy.
Kazuhiko, Kubo   +3 more
openaire   +2 more sources

Role of the aryl hydrocarbon receptor nuclear translocator protein in aryl hydrocarbon (dioxin) receptor action.

Molecular Pharmacology, 1993
Immunoprecipitation experiments performed on cytosolic extracts of the mouse hepatoma cell line Hepa-1c1c7 (Hepa-1) confirm that the 9-S, unliganded, cytosolic aryl hydrocarbon (Ah) receptor complex contains the 90-kDa heat shock protein and the Ah receptor protein but reveal that it does not contain the Ah receptor nuclear translocator (ARNT) protein.
M R, Probst   +4 more
openaire   +2 more sources

Aryl-Hydrocarbon Receptor Nuclear Translocator (ARNT) in Human Skin with Aging

Advances in Gerontology, 2020
The goal of this study was to examine the content of aryl-hydrocarbon receptor nuclear translocator (ARNT) in fibroblasts of human dermis from 20 weeks of pregnancy to the age of 85 years and to define the role of ARNT in age-dependent changes in the fibroblast number in the dermis.
A. G. Gunin   +2 more
openaire   +1 more source

Physicochemical and immunocytochemical analysis of the aryl hydrocarbon receptor nuclear translocator: characterization of two monoclonal antibodies to the aryl hydrocarbon receptor nuclear translocator.

Molecular Pharmacology, 1994
The aryl hydrocarbon receptor nuclear translocator (Arnt) is a basic helix-loop-helix transcription factor that heterodimerizes with the aryl hydrocarbon receptor to mediate signal transduction pathways inducible by 2,3,7,8-tetrachlorodibenzo-p-dioxin and other planar aromatic hydrocarbons.
N G, Hord, G H, Perdew
openaire   +2 more sources

Functional analysis of aryl hydrocarbon receptor nuclear translocator interactions with aryl hydrocarbon receptor in the yeast two-hybrid system

Biochemical Pharmacology, 1995
The aryl hydrocarbon receptor (AHR) mediates dioxin (2,3,7,8-tetrachlorodibenzo-p-dioxin)-induced transcriptional activation of a battery of genes by interaction with a cofactor, called aryl hydrocarbon receptor nuclear translocator (ARNT) protein. Both AHR and ARNT belong to a family of proteins that includes the Drosophila circadian-rhythm protein ...
Y, Yamaguchi, M T, Kuo
openaire   +2 more sources

The citrus flavonone hesperetin attenuates the nuclear translocation of aryl hydrocarbon receptor

Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology, 2018
The environmental polycyclic aromatic hydrocarbons (PAH) and dioxins are carcinogens and their adverse effects have been largely attributed to the activation of AhR. Hesperetin is a flavonone found abundantly in citrus fruits and has been shown to be a biologically active agent.
Yan Qin, Tan   +3 more
openaire   +2 more sources

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