Results 151 to 160 of about 44,282 (308)
Linh P. Nguyen +5 more
openalex +1 more source
Role of the aryl hydrocarbon receptor in carcinogenesis and potential as an anti-cancer drug target
S. Kolluri, U. Jin, S. Safe
semanticscholar +1 more source
Abstract A mouse model of HIV‐associated atherosclerosis (Tg26+/−ApoE−/−) exhibited increased plaque area compared with the ApoE−/− mouse, linked to elevated indoleamine 2,3‐dioxygenase (IDO) activity. IDO catalyses the conversion of tryptophan (TRP) into kynurenine (KYN), measured by the KYN‐to‐TRP ratio.
Marcus V. S. Rangel +5 more
wiley +1 more source
Targeting Tumor Dormancy and Recurrence: Molecular Mechanisms and Peptide Therapeutic Delivery
This review summarizes the molecular mechanisms that regulate tumor dormancy and its role in cancer recurrence, with emphasis on immune evasion, extracellular matrix remodeling, metabolic regulation and angiogenic switching. It further discusses emerging peptide–based therapeutic strategies aimed at detecting, modulating, and eliminating dormant tumor ...
Abdur Raheem Aleem +9 more
wiley +1 more source
On the Nature of Improper Hydrogen Bonding in RCH2F and RCHF2 Motifs
The nature of ‘improper’ hydrogen bonds is explored in FnC─H⋯X systems, such as RCF2H interaction with chloride and water. It is noted that increased fluorination decreases the positive charge density on H but increases it on C, thus these interactions are dominated by electrostatic attraction to C over H.
Bruno A. Piscelli +3 more
wiley +2 more sources
Embryonic and Postnatal Expression of Aryl Hydrocarbon Receptor mRNA in Mouse Brain [PDF]
Eiki Kimura, Chiharu Tohyama
openalex +1 more source
Making Blank Faces Expressive: Chemical Approaches to the Modification of Chemically Inert Peptides
As an alternative to the conventional approach, which combines amino acid monomers in a one‐by‐one fashion to peptide derivatives, the chemical modification of existing peptides has attracted significant attention in recent years. However, such approaches generally target the reactive functional groups in cysteine and lysine residues, particularly in ...
Yoshitaka Moriyama +2 more
wiley +1 more source
Interaction with Nedd8, a Ubiquitin-like Protein, Enhances the Transcriptional Activity of the Aryl Hydrocarbon Receptor [PDF]
Monica Antenos +2 more
openalex +1 more source

