Results 141 to 150 of about 19,957 (224)

Urologic Bacteriome: The Hero or the Villain in Prostate Cancer Onset, Progression, and Treatment?

Medicinal Research Reviews, Volume 46, Issue 4, Page 1111-1151, July 2026.
ABSTRACT Prostate cancer (PCa) is the second most frequently diagnosed cancer in men worldwide and the fifth leading cause of cancer‐related mortality, presenting urgent unmet clinical needs in diagnosis and treatment. The recognition of the microbiome as a key factor in human health has prompted numerous studies, revealing an exciting new approach to ...
Lara R. S. Fonseca, Mariana Feijó, Cátia V. Vaz, Bruno J. Pereira, Sandra Laurentino, Ana Palmeira‐de‐Oliveira, Sílvia Socorro   +6 more
wiley   +1 more source

Aryl hydrocarbon receptor: a multifaceted environmental sensor in liver homeostasis and disease. [PDF]

Front Med (Lausanne)
Jing Y, You X, Feng Y, Wu S, Wang K, Yuan H, Liu J.   +6 more
europepmc   +1 more source

Oxidative Stress Induced Senescent Macrophage‐Driven Squamous Cell Carcinoma Invasion via Glutamine Metabolic Reprogramming

Aging Cell, Volume 25, Issue 7, July 2026.
Oxidative stress induces GLS2‐dependent IL‐1β secretion in senescent macrophages, promoting SCC invasion through the IL‐1β/IL‐1R2 axis. Targeting IL‐1β suppresses invasion more effectively than GLS2 inhibition, highlighting a potential therapeutic strategy for SCC.
Shimeng Wang, Jingtian Mu, Wei Zhao, Can Hu, Xueke Shi, Hongmei Zhou, Junjiang Liu, Fanglong Wu   +7 more
wiley   +1 more source

Cytochrome P450 1a (CYP1A)‐Knockout Javanese Medaka Fish Exhibit Diabetic Traits and Reduced Reproductive Capacity

The FASEB Journal, Volume 40, Issue 12, 30 June 2026.
Analyses of cytochrome P450 1a (CYP1A)‐knockout (KO) Javanese medaka (Oryzias javanicus) revealed that CYP1A is involved in glucose regulation and reproduction. In the KO fish, significant increases in hepatic transcripts of insulin, glucagon, and somatostatin genes, as well as elevated blood glucose, liver mass, and liver triglyceride levels ...
Suhaila Rusni, Yuki Yoshioka, Hilda Mardiana Pratiwi, Toshiyuki Takagi, Muhammad Rahmad Royan, Yuya Hojo, Seiichi Uno, Shinji Kanda, Yusuke Takehana, Masato Kinoshita, Koji Inoue   +10 more
wiley   +1 more source

Extracellular ATP drives tryptophan metabolism and aryl hydrocarbon receptor activation to promote cellular senescence. [PDF]

J Biol Chem
Volonte D, Mullett SJ, Gelhaus SL, Galbiati F.   +3 more
europepmc   +1 more source

Pt/C‐Catalyzed Deuteration of Polycyclic Aromatic Hydrocarbons with Suppressed Arene Hydrogenation

European Journal of Organic Chemistry, Volume 29, Issue 24, 23 June 2026.
An additive‐enabled Pt/C protocol promotes hydrogen–deuterium exchange in fused polycyclic aromatic hydrocarbons (PAHs) in D2O/2‐PrOH at 80 °C. Decalin suppresses undesired ring hydrogenation while accelerating on‐ring H–D exchange, furnishing highly deuterated PAHs (PAHs‐dn).
Naoya Sakurada, Sae Tomoto, Naoki Oka, Tomohiro Ichikawa, Takashi Shigeta, Hironao Sajiki, Takashi Ikawa   +6 more
wiley   +1 more source

1,1‐and 1,2‐Diborylalkenes: Preparation and Synthetic Applications

Advanced Synthesis &Catalysis, Volume 368, Issue 12, 17 June 2026.
In this review, we highlight recent advances in the synthesis and reactivity of 1,1‐diborylalkenes and 1,2‐diborylalkenes, along with various transformations leading to C‐C, C‐heteroatom, and multicomponent products. By providing a comprehensive and practical resource, this review aims to assist researchers in exploring the synthetic utility of 1,1 and
Jayaram Vankudoth, Maruti Mali, Fabienne Berrée   +2 more
wiley   +1 more source

Synthesis of Aromatic Aldehydes by CH Formylation of Aromatics with Silyl Formates Prepared from CO2 and Hydrosilanes

Advanced Synthesis &Catalysis, Volume 368, Issue 12, 17 June 2026.
A new method has been developed for the C–H formylation of aromatic compounds using silyl formates synthesized from CO2 and hydrosilanes. This is the first report on the direct C–H formylation of aromatics with silyl formates. The formylation reactions were promoted by BBr3 or BCl3. The reaction mechanism has been clarified by DFT calculations. Despite
Natsumi Nitta, Kei Hirokawa, So Saibara, Bikash Dev Nath, Kazuto Takaishi, Tadashi Ema   +5 more
wiley   +1 more source

Braking the system: the aryl hydrocarbon receptor controls monocytes in homeostasis. [PDF]

J Clin Invest
Kenison JE, Quintana FJ.
europepmc   +1 more source

Electrodeposited MnCo and MnNiCo Spinels for Anion Exchange Membrane Direct Ammonia Fuel Cell Cathodes: An Alternative to Platinum

ChemSusChem, Volume 19, Issue 11, 15 June 2026.
Electrodeposited MnCoOX and MnNiCoOX spinels on Ni foam are evaluated as binder‐free, platinum group metal‐free cathodes in direct ammonia fuel cells. MnCoOX matches and surpasses Pt in oxygen reduction performance while tolerating ammonia crossover, whereas Ni incorporation dilutes the active Co–Mn sites and degrades performance.
Mehmet Turan Görüryilmaz, Karuppasamy Dharmaraj, Iris Dorbandt, Erno Kemppainen, Thorsten Schultz, Norbert Koch, Xuyun Guo, Valeria Nicolosi, Rutger Schlatmann, Michelle P. Browne, Sonya Calnan   +10 more
wiley   +1 more source